公开(公告)号：US20110038887A1

公开(公告)日：2011-02-17

申请号：US12225396

申请日：2007-03-14

Applicant: Roland Contreras ,  Kristof De Vusser ,  Silvia Revelli

Inventor： Roland Contreras ,  Kristof De Vusser ,  Silvia Revelli

IPC: A61K39/005 ,  C07K14/44 ,  C07K19/00 ,  A61P33/02

CPC classification number: A61K39/005 ,  A61K38/16 ,  C07K14/44 ,  Y02A50/414

Abstract: The present invention relates to a vaccine against Trypanosoma cruzi infection, useful in the prevention and/or treatment of the Chagas disease. More specifically, the present invention relates to a recombinant mutant trans-sialidase enzyme that can be used as an efficient vaccine, without side effects.

Abstract translation: 本发明涉及可用于预防和/或治疗恰加斯病的克氏锥虫感染疫苗。 更具体地，本发明涉及可用作有效疫苗的重组突变体唾液酸酶，无副作用。

公开(公告)号：US09028844B2

公开(公告)日：2015-05-12

申请号：US12225396

申请日：2007-03-14

Applicant: Roland Contreras ,  Kristof De Vusser ,  Silvia Revelli

Inventor： Roland Contreras ,  Kristof De Vusser ,  Silvia Revelli

IPC: A61K39/005 ,  A61K38/16 ,  C12N9/00 ,  C07K14/44

CPC classification number: A61K39/005 ,  A61K38/16 ,  C07K14/44 ,  Y02A50/414

Abstract: The present invention relates to a vaccine against Trypanosoma cruzi infection, useful in the prevention and/or treatment of the Chagas disease. More specifically, the present invention relates to a recombinant mutant trans-sialidase enzyme that can be used as an efficient vaccine, without side effects.

Abstract translation: 本发明涉及可用于预防和/或治疗恰加斯病的克氏锥虫感染疫苗。 更具体地，本发明涉及可用作有效疫苗的重组突变体唾液酸酶，无副作用。