公开(公告)号：US10976302B2

公开(公告)日：2021-04-13

申请号：US16868457

申请日：2020-05-06

Applicant: Roche Sequencing Solutions, Inc.

Inventor： Roger J. A. Chen ,  Jennifer Hovis ,  Hui Tian

IPC: G01N33/487

Abstract: A nanopore sequencing device is disclosed. The nanopore sequencing device includes a working electrode. It further includes a dielectric layer, wherein a portion of the dielectric layer is disposed horizontally adjacent to the working electrode and a portion of the dielectric layer is disposed above and covering a portion of the working electrode, and wherein the dielectric layer forms a well having an opening above an uncovered portion of the working electrode. A base surface area of the working electrode is greater than a base surface area of the opening above the uncovered portion of the working electrode.

公开(公告)号：US20190293624A1

公开(公告)日：2019-09-26

申请号：US16424114

申请日：2019-05-28

Applicant: Roche Sequencing Solutions, Inc.

Inventor： Roger J.A. Chen ,  Jennifer Hovis ,  Hui Tian

IPC: G01N33/487

Abstract: A nanopore sequencing device is disclosed. The nanopore sequencing device includes a working electrode. It further includes a dielectric layer, wherein a portion of the dielectric layer is disposed horizontally adjacent to the working electrode and a portion of the dielectric layer is disposed above and covering a portion of the working electrode, and wherein the dielectric layer forms a well having an opening above an uncovered portion of the working electrode. A base surface area of the working electrode is greater than a base surface area of the opening above the uncovered portion of the working electrode.

公开(公告)号：US20200264160A1

公开(公告)日：2020-08-20

申请号：US16868457

申请日：2020-05-06

Applicant: Roche Sequencing Solutions, Inc.

Inventor： Roger J.A. Chen ,  Jennifer Hovis ,  Hui Tian

IPC: G01N33/487

Abstract: A nanopore sequencing device is disclosed. The nanopore sequencing device includes a working electrode. It further includes a dielectric layer, wherein a portion of the dielectric layer is disposed horizontally adjacent to the working electrode and a portion of the dielectric layer is disposed above and covering a portion of the working electrode, and wherein the dielectric layer forms a well having an opening above an uncovered portion of the working electrode. A base surface area of the working electrode is greater than a base surface area of the opening above the uncovered portion of the working electrode.

公开(公告)号：US10684270B2

公开(公告)日：2020-06-16

申请号：US16424114

申请日：2019-05-28

Applicant: Roche Sequencing Solutions, Inc.

Inventor： Roger J.A. Chen ,  Jennifer Hovis ,  Hui Tian

IPC: G01N33/487

Abstract: A nanopore sequencing device is disclosed. The nanopore sequencing device includes a working electrode. It further includes a dielectric layer, wherein a portion of the dielectric layer is disposed horizontally adjacent to the working electrode and a portion of the dielectric layer is disposed above and covering a portion of the working electrode, and wherein the dielectric layer forms a well having an opening above an uncovered portion of the working electrode. A base surface area of the working electrode is greater than a base surface area of the opening above the uncovered portion of the working electrode.