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公开(公告)号：US20160002598A1
公开(公告)日：2016-01-07
申请号：US14761828
申请日：2014-01-28
申请人： Chirstopher CENTENO , Brian J. LEACH , Ryan DREGALLA , Patrick REISCHLING , Nicolette LYONS , REGENERATIVE SCIENCES, LLC
CPC分类号： C12N5/0644 , A61K35/19 , A61K45/06 , C12M23/28 , C12M27/10 , C12M29/00 , C12M35/00 , C12M35/04 , C12M47/06 , C12N13/00 , C12N2521/10 , C12N2523/00 , G01N33/86
摘要： Device, system and method embodiments are disclosed herein which provide for the production of a modified autologous platelet solution at the patient bedside for contemporaneous reinjection to the patient. In certain embodiments all of the steps including, but not limited to blood draw, platelet lysis, solution preparation and reinjection to a patient may be accomplished in a single office or clinic visit without relocating the patient. Accordingly, the apparatus, devices and systems disclosed herein generally include a substantially stand-alone machine, device or system which is configured to accept a platelet containing solution, induce lysis of one or more platelet bodies within the platelet containing solution and provide the resulting modified platelet solution in a manner suitable for injection into the patient.
摘要翻译： 本文公开了装置，系统和方法实施例，其提供在患者床边生产改良的自体血小板溶液以同时再次注射给患者。 在某些实施方案中，包括但不限于抽血，血小板裂解，溶液制备和注射给患者的所有步骤可以在单独的办公室或诊所访问中完成，而不需要重新定位患者。 因此，本文公开的装置，装置和系统通常包括基本上独立的机器，装置或系统，其被配置为接受含血小板的溶液，诱导溶解含血小板的溶液中的一个或多个血小板体，并提供所得到的修饰 血小板溶液以适合注射入患者的方式。
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公开(公告)号：US09976115B2
公开(公告)日：2018-05-22
申请号：US14778530
申请日：2014-08-06
CPC分类号： C12M45/04 , A61M1/029 , A61M2202/08 , A61M2202/10 , B01L3/50215 , B01L2300/0864 , C12M33/04 , C12N5/0669
摘要： The embodiments disclosed herein generally relate to systems, devices and methods for the fractionation, isolation, extraction and processing of the adipose supernatant layer of a bone marrow aspirate. In particular, the various embodiments relate to systems devices and methods of obtaining, utilizing and processing the adipose supernatant layer of a bone marrow aspirate as a source of mesenchymal stem cells.
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公开(公告)号：US20160298076A1
公开(公告)日：2016-10-13
申请号：US14778530
申请日：2014-08-06
CPC分类号： C12M45/04 , A61M1/029 , A61M2202/08 , A61M2202/10 , B01L3/50215 , B01L2300/0864 , C12M33/04 , C12N5/0669
摘要： The embodiments disclosed herein generally relate to systems, devices and methods for the fractionation, isolation, extraction and processing of the adipose supernatant layer of a bone marrow aspirate. In particular, the various embodiments relate to systems devices and methods of obtaining, utilizing and processing the adipose supernatant layer of a bone marrow aspirate as a source of mesenchymal stem cells.
摘要翻译： 本文公开的实施方案一般涉及用于骨髓抽吸物的脂肪上清液层的分离，分离，提取和加工的系统，装置和方法。 特别地，各种实施方案涉及获得，利用和处理作为间充质干细胞来源的骨髓抽吸物的脂肪上清层的系统装置和方法。
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