公开(公告)号：US10545157B2

公开(公告)日：2020-01-28

申请号：US15026577

申请日：2014-10-06

Applicant: Randox Teoranta

Inventor： Ivan McConnell ,  Ciaran Richardson ,  John Lamont ,  Stephen Peter Fitzgerald

IPC: G01N31/00 ,  G01N33/53 ,  G01N33/68

Abstract: The disclosure provides methods and solid states devices for detecting and staging chronic kidney disease in a patient, where the levels of biomarkers in a sample obtained from a patient are elevated or reduced compared to the levels in a sample obtained from healthy subject. In addition, the disclosure provides the use of methods and solid state devices for measurement of specific biological markers for determining the efficacy of a treatment for chronic kidney disease and for determining a drug treatment protocol for a subject suffering from chronic kidney disease.

公开(公告)号：US20190293662A1

公开(公告)日：2019-09-26

申请号：US16462924

申请日：2017-11-23

Applicant: Randox Laboratories Ltd ,  Randox Teoranta

Inventor： Ciaran Richardson ,  Ivan McConnell ,  John Lamont ,  Stephen Peter Fitzgerald

IPC: G01N33/68 ,  C07K16/18

Abstract: Described are methods and kits for diagnosing stroke using GFAP derivatives.

公开(公告)号：US20160216278A1

公开(公告)日：2016-07-28

申请号：US15026577

申请日：2014-10-06

Applicant: RANDOX TEORANTA

Inventor： Ivan McConnell ,  Ciaran Richardson ,  John Lamont ,  Stephen Peter Fitzgerald

IPC: G01N33/68

Abstract: The present invention provides methods and solid state devices for detecting and staging chronic kidney disease in a patient, where the levels of biomarkers in a sample obtained from a patient are elevated or reduced compared to the levels in a sample obtained from healthy subject.The invention also relates to the use of methods and solid state devices for measurement of specific biological markers for determining the efficacy of a treatment for chronic kidney disease and for determining a drug treatment protocol for a subject suffering from chronic kidney disease.

Abstract translation: 本发明提供了用于检测和分期患者慢性肾脏疾病的方法和固态装置，其中从患者获得的样品中的生物标志物的水平与从健康受试者获得的样品中的水平相比升高或降低。 本发明还涉及方法和固态装置用于测量特异性生物标志物以确定慢性肾脏疾病治疗功效以及确定患有慢性肾脏疾病的受试者的药物治疗方案的用途。