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Patent Agency Ranking
1.发明公开公开(公告)号：US20240327865A1
公开(公告)日：2024-10-03
申请号：US18577545
申请日：2022-07-08
Applicant: REPLICATE BIOSCIENCE, INC.
IPC: C12N15/86 , A01K67/0275 , A61K9/00 , A61K9/51 , A61K38/00 , A61K39/00 , A61K48/00 , A61P31/00 , C07K14/005 , C12N7/00 , C12N15/88
CPC classification number: C12N15/86 , A01K67/0275 , A61K9/0019 , A61K9/5123 , A61K48/0041 , A61P31/00 , C07K14/005 , C12N7/00 , C12N15/88 , A01K2267/01 , A61K38/00 , A61K39/00 , A61K2039/53 , C12N2770/36122 , C12N2770/36134 , C12N2770/36143
Abstract: The present disclosure relates to the field of molecular virology, including nucleic acid molecules comprising modified viral genomes or replicons (e.g., self-replicating RNAs), pharmaceutical compositions containing the same, and the use of such nucleic acid molecules and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for eliciting an immune response in a subject in need thereof, as well as methods for preventing and/or treating various health conditions.
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公开(公告)号：US20250027110A1
公开(公告)日：2025-01-23
申请号：US18713901
申请日：2022-11-28
Applicant: Replicate Bioscience, Inc.
Abstract: The present disclosure relates to the field of molecular virology, and particularly relates to nucleic acid molecules encoding a modified equine encephalitis virus viral genome or self-replicating RNA (srRNA) construct, pharmaceutical compositions containing the same, and the use of such nucleic acid molecules and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for eliciting an immune response in a subject in need thereof, as well as methods for preventing and/or treating cancer.
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公开(公告)号：US20230167459A1
公开(公告)日：2023-06-01
申请号：US17537211
申请日：2021-11-29
Applicant: Replicate Bioscience, Inc.
CPC classification number: C12N15/86 , C07K14/5434 , A61K9/5123 , C12N2770/36143
Abstract: The present disclosure relates to the field of molecular virology, and particularly relates to nucleic acid molecules encoding a modified alphavirus virus viral genome or self-replicating RNA (srRNA) construct, pharmaceutical compositions containing the same, and the use of such nucleic acid molecules and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for eliciting a pharmacodynamics effect in a subject.
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公开(公告)号：US20250027109A1
公开(公告)日：2025-01-23
申请号：US18713851
申请日：2022-11-28
Applicant: Replicate Bioscience, Inc.
Abstract: The present disclosure relates to the field of molecular virology, and particularly relates to nucleic acid molecules encoding a modified alphavirus virus viral genome or self-replicating RNA (srRNA) construct, pharmaceutical compositions containing the same, and the use of such nucleic acid molecules and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for eliciting a pharmacodynamics effect in a subject.
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公开(公告)号：US20250019745A1
公开(公告)日：2025-01-16
申请号：US18714038
申请日：2022-11-28
Applicant: Replicate Bioscience, Inc.
IPC: C12Q1/6809
Abstract: The present disclosure generally relates to new processes for generating self-replicating RNA (srRNA) systems with superior expression properties. The disclosure also provides nucleic acids and recombinant cells expressing such srRNA constructs as well as pharmaceutical compositions containing the same. Further provided are compositions and methods for inducing pharmacodynamic effects in a subject and for the prevention and/or treatment of various health conditions.
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