-
公开(公告)号：US11730804B1
公开(公告)日：2023-08-22
申请号：US17720002
申请日：2022-04-13
Applicant: Replicate Bioscience, Inc.
CPC classification number: A61K39/12 , C12N7/00 , C12N15/86 , A61K2039/5256 , A61K2039/5258 , C12N2770/36122 , C12N2770/36134 , C12N2770/36143 , C12N2770/36145 , C12N2770/36162
Abstract: The present disclosure relates generally to the field of molecular virology, and particularly relates to nucleic acid molecules encoding a modified alphavirus virus viral genome or self-replicating RNA (srRNA) construct, recombinant cells and pharmaceutical compositions containing the same, as well as the use of such nucleic acid molecules, recombinant cells and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for eliciting an immune response in a subject in need thereof, as well as methods for preventing and/or treating rabies virus infection.
-
公开(公告)号：US20240400619A1
公开(公告)日：2024-12-05
申请号：US18688697
申请日：2022-09-01
Applicant: Replicate Bioscience, Inc.
Inventor： Nathaniel Stephen WANG , Shigeki Joseph MIYAKE-STONER
IPC: C07K14/005 , A61K39/00 , A61P31/16 , C12N15/86
Abstract: The present disclosure relates to the field of molecular virology, including nucleic acid molecules comprising modified viral genomes or replicons (e.g., self-replicating RNAs), pharmaceutical compositions containing the same, and the use of such nucleic acid molecules and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for eliciting an immune response in a subject in need thereof, as well as methods for preventing and/or treating various health conditions.
-
公开(公告)号：US20250027110A1
公开(公告)日：2025-01-23
申请号：US18713901
申请日：2022-11-28
Applicant: Replicate Bioscience, Inc.
Abstract: The present disclosure relates to the field of molecular virology, and particularly relates to nucleic acid molecules encoding a modified equine encephalitis virus viral genome or self-replicating RNA (srRNA) construct, pharmaceutical compositions containing the same, and the use of such nucleic acid molecules and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for eliciting an immune response in a subject in need thereof, as well as methods for preventing and/or treating cancer.
-
公开(公告)号：US20230167459A1
公开(公告)日：2023-06-01
申请号：US17537211
申请日：2021-11-29
Applicant: Replicate Bioscience, Inc.
CPC classification number: C12N15/86 , C07K14/5434 , A61K9/5123 , C12N2770/36143
Abstract: The present disclosure relates to the field of molecular virology, and particularly relates to nucleic acid molecules encoding a modified alphavirus virus viral genome or self-replicating RNA (srRNA) construct, pharmaceutical compositions containing the same, and the use of such nucleic acid molecules and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for eliciting a pharmacodynamics effect in a subject.
-
公开(公告)号：US20250027109A1
公开(公告)日：2025-01-23
申请号：US18713851
申请日：2022-11-28
Applicant: Replicate Bioscience, Inc.
Abstract: The present disclosure relates to the field of molecular virology, and particularly relates to nucleic acid molecules encoding a modified alphavirus virus viral genome or self-replicating RNA (srRNA) construct, pharmaceutical compositions containing the same, and the use of such nucleic acid molecules and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for eliciting a pharmacodynamics effect in a subject.
-
Patent Agency Ranking
公开(公告)号：US20250019745A1
公开(公告)日：2025-01-16
申请号：US18714038
申请日：2022-11-28
Applicant: Replicate Bioscience, Inc.
IPC: C12Q1/6809
Abstract: The present disclosure generally relates to new processes for generating self-replicating RNA (srRNA) systems with superior expression properties. The disclosure also provides nucleic acids and recombinant cells expressing such srRNA constructs as well as pharmaceutical compositions containing the same. Further provided are compositions and methods for inducing pharmacodynamic effects in a subject and for the prevention and/or treatment of various health conditions.
-
公开(公告)号：US20230398200A1
公开(公告)日：2023-12-14
申请号：US18007036
申请日：2021-07-30
Applicant: Replicate Bioscience, Inc.
Inventor： Nathaniel Stephen WANG , Shigeki Joseph MIYAKE-STONER
CPC classification number: A61K39/12 , C12N15/86 , C12N15/88 , A61K45/06 , A61K2039/53 , C12N2770/36143 , C12N2770/36162 , C12N2770/36171 , C12N2770/36134
Abstract: The present disclosure relates to the field of molecular virology, including nucleic acid molecules comprising modified viral genomes or replicons, pharmaceutical compositions containing the same, and the use of such nucleic acid molecules and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for eliciting an immune response in a subject in need thereof, as well as methods for preventing and/or treating various health conditions.
-
8.发明公开公开(公告)号：US20240327865A1
公开(公告)日：2024-10-03
申请号：US18577545
申请日：2022-07-08
Applicant: REPLICATE BIOSCIENCE, INC.
IPC: C12N15/86 , A01K67/0275 , A61K9/00 , A61K9/51 , A61K38/00 , A61K39/00 , A61K48/00 , A61P31/00 , C07K14/005 , C12N7/00 , C12N15/88
CPC classification number: C12N15/86 , A01K67/0275 , A61K9/0019 , A61K9/5123 , A61K48/0041 , A61P31/00 , C07K14/005 , C12N7/00 , C12N15/88 , A01K2267/01 , A61K38/00 , A61K39/00 , A61K2039/53 , C12N2770/36122 , C12N2770/36134 , C12N2770/36143
Abstract: The present disclosure relates to the field of molecular virology, including nucleic acid molecules comprising modified viral genomes or replicons (e.g., self-replicating RNAs), pharmaceutical compositions containing the same, and the use of such nucleic acid molecules and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for eliciting an immune response in a subject in need thereof, as well as methods for preventing and/or treating various health conditions.
-
公开(公告)号：US20240218395A1
公开(公告)日：2024-07-04
申请号：US18555852
申请日：2022-04-20
Applicant: REPLICATE BIOSCIENCE, INC.
IPC: C12N15/86 , A61K39/00 , A61K39/145 , A61P31/16 , C07K14/005
CPC classification number: C12N15/86 , A61K39/145 , A61P31/16 , C07K14/005 , A61K2039/5256 , A61K2039/53 , A61K2039/55555 , C12N2760/16034 , C12N2760/16071 , C12N2770/36143 , C12N2800/70 , C12N2830/42 , C12N2830/50 , C12N2840/203
Abstract: The present disclosure relates to the field of molecular virology, including nucleic acid molecules comprising modified viral genomes or replicons (e.g., self-replicating RNAs), pharmaceutical compositions containing the same, and the use of such nucleic acid molecules and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for modulating an immune response in a subject in need thereof, as well as methods for preventing and/or treating various health conditions.
-
公开(公告)号：US11873507B2
公开(公告)日：2024-01-16
申请号：US17537211
申请日：2021-11-29
Applicant: Replicate Bioscience, Inc.
CPC classification number: C12N15/86 , A61K9/5123 , C07K14/5434 , C12N2770/36143
Abstract: The present disclosure relates to the field of molecular virology, and particularly relates to nucleic acid molecules encoding a modified alphavirus virus viral genome or self-replicating RNA (srRNA) construct, pharmaceutical compositions containing the same, and the use of such nucleic acid molecules and compositions for production of desired products in cell cultures or in a living body. Also provided are methods for eliciting a pharmacodynamics effect in a subject.
-
-
-
-
-
-
-
-
-
Search Results
11
records
(took 0.012 seconds)
