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公开(公告)号：US20220305018A1
公开(公告)日：2022-09-29
申请号：US17694642
申请日：2022-03-14
发明人： Cyril Bucher , Adrian Dukes , Blanca Gomez , Hannah Haley , Dennis Hu , Jeffrey J. Jackson , Michelle Yoo Min Ko , Paul Leger , Anqi Ma , Andrew A. Ng , Daniel Poon , Omar Robles , Anton Shakhmin , Grant Shibuya , Parcharee Tivitmahaisoon , Vi-Anh Vu , David J. Wustrow , Mikhail Zibinsky
IPC分类号： A61K31/519 , A61K45/06 , C07D487/04 , C07D519/00
摘要： Disclosed herein are pyrazole pyrimidine compounds that modulate and/or inhibit hematopoietic progenitor kinase 1, as well as methods of making such compounds and therapeutic methods of using same.
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公开(公告)号：US11918582B2
公开(公告)日：2024-03-05
申请号：US17694642
申请日：2022-03-14
发明人： Cyril Bucher , Adrian Dukes , Blanca Gomez , Hannah Haley , Dennis Hu , Jeffrey J. Jackson , Michelle Yoo Min Ko , Paul Leger , Anqi Ma , Andrew A. Ng , Daniel Poon , Omar Robles , Anton Shakhmin , Grant Shibuya , Parcharee Tivitmahaisoon , Vi-Anh Vu , David J. Wustrow , Mikhail Zibinsky
IPC分类号： A61K31/519 , A61K45/06 , C07D487/04 , C07D519/00
CPC分类号： A61K31/519 , A61K45/06 , C07D487/04 , C07D519/00
摘要： Disclosed herein are pyrazole pyrimidine compounds that modulate and/or inhibit hematopoietic progenitor kinase 1, as well as methods of making such compounds and therapeutic methods of using same.
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公开(公告)号：US11046699B2
公开(公告)日：2021-06-29
申请号：US16431504
申请日：2019-06-04
发明人： Minna H. T. Bui , Adrian O. Dukes , Xinping Han , Dennis X. Hu , Jeffrey J. Jackson , Yoo Min Ko , Paul R. Leger , Anqi Ma , Jack Maung , Andrew A. Ng , Akinori Okano , Omar Robles , Grant Shibuya , Hunter P. Shunatona , Jacob B. Schwarz , Anton A. Shakhmin , David J. Wustrow , Mikhail Zibinsky
IPC分类号： C07D487/04 , C07D519/00
摘要： Disclosed herein are pyrozolo-pyrimidin-amino-cycloalkyl compounds, analogs thereof, pharmaceutical compositions comprising thereof and therapeutic uses therefor.
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