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公开(公告)号：US20140142221A1
公开(公告)日：2014-05-22
申请号：US14113049
申请日：2012-04-09
IPC分类号： C09K8/48
CPC分类号： C09K8/48 , C04B20/1033 , C04B20/1037 , C04B28/02 , C04B40/0039 , C04B2103/52 , C09K8/03 , C04B14/10 , C04B14/26 , C04B14/368 , C04B22/142 , C04B14/30 , C04B20/026 , C04B24/223 , C04B24/226 , C04B2103/408 , C04B20/008 , C04B24/22
摘要： A weighting agent composition for use in a cement slurry for downhole operations in a subterranean well, the composition comprising a finely divided solid weighting agent; and a dispersant comprising a sulphonic acid, salt or derivative thereof, the sulphonic acid having the general formula I: -[A(OSOO−M+)-B-A′(OSOO−M+)]n- (I) wherein A and A′ are each an aromatic moiety; B is an aliphatic moiety; OSOO−M+ is a solubilising group consisting of sulphonic acid, a salt or derivative thereof; and n is an integer of at least 2. The composition is of particular use in formulating a cement slurry for use in a downhole cementing operation. There is also provided a method of preparing a finely divided weighting agent using the sulphonic acid of formula I, a cement formulation comprising the composition and a method of cementing a subterranean well.
摘要翻译： 一种用于在地下井中进行井下作业的水泥浆料中的加重剂组合物，该组合物包含细碎的固体增重剂; 和包含磺酸，其盐或衍生物的磺化物，具有通式I的磺酸： - [A（OSOO-M +） - BA'（OSOO-M +）] n - （I）其中A和A' 每个是芳族部分; B是脂肪族部分; OSOO-M +是由磺酸，其盐或衍生物组成的增溶组; n是至少为2的整数。该组合物特别用于配制用于井下固井操作的水泥浆料。 还提供了使用式I的磺酸制备细碎加重剂的方法，包含该组合物的水泥配方和一种固井地下井的方法。
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2.发明授权Methods and systems for purchasing and inventory of paper and extended media products 失效纸张和扩展媒体产品的采购和库存方法和系统公开(公告)号：US06876980B2
公开(公告)日：2005-04-05
申请号：US10112874
申请日：2002-04-02
CPC分类号： G06Q10/06 , G06Q10/087 , G06Q10/0875 , G06Q20/203
摘要： A system and method in a network-based inventory management system for providing information concerning inventory amounts and inventory ordering to at least one computer. In operation, a server first receives an inventory amount of an item from a first plurality of clients. Next, the server receives an inventory amount of the item from a second plurality of clients. Once the server has the two amounts, it analyzes the inventories at said first and second plurality of computers to determine from which of the first plurality of computers to order the item and to which of the second plurality of computers the ordered item is to be transferred.
摘要翻译： 一种基于网络的库存管理系统中的系统和方法，用于向至少一台计算机提供关于库存量和库存订单的信息。 在操作中，服务器首先从第一多个客户端接收项目的库存量。 接下来，服务器从第二多个客户端接收项目的库存量。 一旦服务器具有两个量，它分析在所述第一和第二多个计算机处的库存，以确定从第一多个计算机中的哪个计算机订购该物品以及第二个多个计算机中的哪个计算机将要传送订购的物品 。
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公开(公告)号：US4273800A
公开(公告)日：1981-06-16
申请号：US963239
申请日：1978-11-24
申请人： Paul Reid
发明人： Paul Reid
CPC分类号： C23C2/24
摘要： The invention provides a method for removal of an excess of a liquid metal coating from a substrate, such as a hot dip coated metal substrate, and in preferred embodiments, for control of metal coating thickness.The method involves moving the substrate through a stationary pulsating or alternating magnetic flux. The flux is directed in a path which enters the coating at an entry zone and exits from the coating at an exit zone, those zones being on the external surface of the coating and spaced apart in the direction of advance of the substrate. The frequency and intensity of the flux are controlled so as to exert on the coating surface a force opposing the viscous drag forces exerted in the coating by the moving substrate. Apparatus for use in performing the method is described.
摘要翻译： 本发明提供一种从基底（例如热浸镀金属基底）上去除过量的液态金属涂层的方法，并且在优选实施例中用于控制金属涂层厚度。 该方法涉及使基板移动通过固定的脉动或交变磁通。 焊剂被引导到在入口区域进入涂层并在出口区域处从涂层排出的路径，那些区域在涂层的外表面上并且沿着衬底的前进方向间隔开。 控制焊剂的频率和强度，以便在涂层表面上施加与由移动的基材施加在涂层中的粘性阻力相反的力。 描述了用于执行该方法的装置。
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公开(公告)号：US20100113445A1
公开(公告)日：2010-05-06
申请号：US12531760
申请日：2008-03-12
IPC分类号： A61K31/5377 , C07D403/04 , C07D239/49 , C07D239/48 , C07D413/14 , C07D403/14 , A61K31/505 , A61K31/496 , A61P35/00
CPC分类号： C07D403/04 , C07D239/48 , C07D401/04 , C07D403/14 , C07D405/04 , C07D409/04 , C07D413/14 , C07D417/14 , C07D471/04
摘要： The present invention relates to dianilinopyrimidine derivatives, compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such dianilinopyrimidine derivatives are useful in the treatment of diseases associated with inappropriate Wee1 kinase activity.
摘要翻译： 本发明涉及二苯胺基嘧啶衍生物，含有它们的组合物和药物，以及这些化合物，组合物和药物的制备和使用方法。 这种二苯胺基嘧啶衍生物可用于治疗与不适当的Wee1激酶活性相关的疾病。
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公开(公告)号：US20100105674A1
公开(公告)日：2010-04-29
申请号：US12531763
申请日：2008-03-12
IPC分类号： A61K31/5377 , A61K31/506 , C07D413/14 , C07D413/12 , C07D403/04 , C07D239/48 , C07D403/12 , A61P35/00 , C07D401/12 , A61K31/505
CPC分类号： C07D239/42 , A61K31/505 , C07D239/48 , C07D401/04 , C07D403/12
摘要： The present invention relates to dianilinopyrimidine derivatives, compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such dianilinopyrimidine derivatives are useful in the treatment of diseases associated with inappropriate Wee1 kinase activity.
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公开(公告)号：US07554522B2
公开(公告)日：2009-06-30
申请号：US11021415
申请日：2004-12-23
申请人： Robert E. Sinclair, II , Gilma Annuska Perkins , Michael Edward Dulac Winser , Ramkumar Subramanian , Paul Reid
发明人： Robert E. Sinclair, II , Gilma Annuska Perkins , Michael Edward Dulac Winser , Ramkumar Subramanian , Paul Reid
IPC分类号： G06F3/00
CPC分类号： G06F3/0481 , G06F2203/04801
摘要： A computing environment can dynamically respond to user preferences and personal abilities by enabling computer users to configure their computing experience by implicitly gathering information about the users' needs. The system can detect users' issues during the natural course of interaction with the system and offer to make adjustments to make their tasks simpler and more enjoyable. The system can allow for the configuration of settings that can impact users' abilities to receive important information from the system or provide input to the system.
摘要翻译： 计算环境可以通过使计算机用户通过隐含地收集有关用户需求的信息来配置他们的计算体验来动态地响应用户偏好和个人能力。 该系统可以在与系统交互的自然过程中检测用户的问题，并提出调整，使其任务更简单，更愉快。 该系统可以配置可能影响用户从系统接收重要信息或向系统提供输入的能力的设置。
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公开(公告)号：US20080156535A1
公开(公告)日：2008-07-03
申请号：US11618091
申请日：2006-12-29
申请人： Paul Reid
发明人： Paul Reid
IPC分类号： E21B47/08
CPC分类号： E21B47/08 , E21B17/1021 , E21B33/138
摘要： A treatment apparatus and method for wellbore instability is described including a caliper with one or more radially extending arms which are capable of extending and retracting movement in a radial direction and a fluid supply facility to deliver treatment fluid from the ends of the arms to the wellbore wall, with a sensing and valve mechanism such that in use fluid is being delivered from the end of any extended arm to a breakout region of the wellbore where there is instability.
摘要翻译： 描述了一种用于井筒不稳定性的处理装置和方法，其包括具有一个或多个径向延伸的臂的卡钳，其能够沿径向方向延伸和缩回运动，以及流体供应设施，以将治疗流体从臂的端部输送到井筒 具有感测和阀机构，使得在使用中，流体从任何延伸的臂的端部被输送到井筒的不稳定的断裂区域。
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公开(公告)号：US20050031608A1
公开(公告)日：2005-02-10
申请号：US10636458
申请日：2003-08-06
申请人： Paul Reid , Laurence Raymond
发明人： Paul Reid , Laurence Raymond
CPC分类号： A61K35/58 , A61K38/1703
摘要： The disclosed invention is a composition of matter, a process of production thereof, and a method for the treatment of chronic pain, especially to the treatment of heretofore intractable pain as associated with advanced cancer, neurological conditions and rheumatoid arthritis. The treatment of pain associated with viral infections and lesions are also within the contemplation of the present invention. The composition of matter comprises modified alpha-neurotoxins or modified venoms known to contain alpha-neurotoxins in an acceptable carrier for either parenteral, oral or topical administration.
摘要翻译： 所公开的发明是物质的组合物，其制备方法，以及用于治疗慢性疼痛的方法，特别是治疗与晚期癌症，神经病症和类风湿性关节炎相关的迄今难以治疗的疼痛。 与病毒感染和损伤相关的疼痛的治疗也在本发明的考虑之内。 物质的组成包括已知在可接受的载体中含有α-神经毒素的经修饰的α-神经毒素或修饰的毒液，用于肠胃外，口服或局部给药。
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公开(公告)号：US20080081048A1
公开(公告)日：2008-04-03
申请号：US11540862
申请日：2006-10-02
申请人： Laurence Raymond , Paul Reid
发明人： Laurence Raymond , Paul Reid
IPC分类号： A61K39/08 , C07K14/195
摘要： The invention provides improved methods of making compositions comprising detoxified neurotropically active modified neurotoxins derived from snake venom, and compositions made using these methods. The compositions are useful for the treatment of a wide variety of neurological and viral diseases.
摘要翻译： 本发明提供了制备组合物的改进方法，所述组合物包含衍生自蛇毒的解毒神经营养改性神经毒素，以及使用这些方法制备的组合物。 该组合物可用于治疗各种神经病毒和病毒性疾病。
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公开(公告)号：US20060088858A1
公开(公告)日：2006-04-27
申请号：US11217713
申请日：2005-09-02
申请人： Paul Reid , Laurence Raymond
发明人： Paul Reid , Laurence Raymond
CPC分类号： A61K35/58 , A61K38/1703
摘要： The present invention relates to a class of proteins, and a method for treatment of neurological and viral diseases in humans and animals. More specifically it applies to the treatment of heretofore intractable diseases such as retro-viral infections including human immunodeficiency virus (HIV), simian immunodeficiency virus (SIV), feline immunodeficiency virus (FIV), bovine immunodeficiency virus (BIV) and equine acquired immunodeficiency virus (EAIV). The method of treatment comprises administering to the subject a disease mitigating amount of a detoxified modified venom composition.
摘要翻译： 本发明涉及一类蛋白质，以及用于治疗人和动物神经病毒和病毒性疾病的方法。 更具体地说，它适用于治疗迄今为止的难治性疾病，例如包括人类免疫缺陷病毒（HIV），猿猴免疫缺陷病毒（SIV），猫免疫缺陷病毒（FIV），牛免疫缺陷病毒（BIV）和马获得性免疫缺陷病毒 （EAIV）。 治疗方法包括向受试者施用减轻疾病的量的解毒改良的毒液组合物。
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