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公开(公告)号：US20100236556A1
公开(公告)日：2010-09-23
申请号：US12765380
申请日：2010-04-22
IPC分类号： A61M16/00
CPC分类号： A61M16/0069 , A61M16/024 , A61M2016/0027 , A61M2016/0039 , A61M2230/04
摘要： A method and apparatus that provides an expert system for determining respiratory phase during ventilatory support of a subject. Discrete phase states are partitioned and prior probability functions and observed probability functions for each state are defined. The probability functions are based upon relative duration of each state as well as the flow characteristics of each state. These functions are combined to determine phase probabilities for each state using Bayes' theorem. The calculated probabilities for the states may then be compared to determine which state the subject is experiencing. A ventilator may then conform respiratory support in accordance with the most probable phase. To provide a learning feature, the probability functions may be adjusted during use to provide a more subject specific response that accounts for changing respiratory characteristics.
摘要翻译： 一种提供用于在受试者的通气支持期间确定呼吸相位的专家系统的方法和装置。 离散相位状态被划分，并且定义了每个状态的先验概率函数和观测概率函数。 概率函数基于每个状态的相对持续时间以及每个状态的流量特性。 这些功能被组合以使用贝叶斯定理确定每个状态的相位概率。 然后可以比较所计算的状态概率，以确定受试者正在经历的状态。 然后呼吸机可以根据最可能的阶段来符合呼吸支持。 为了提供学习特征，在使用期间可以调整概率函数以提供考虑到呼吸特征变化的更多受试者特异性响应。
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公开(公告)号：US06997881B2
公开(公告)日：2006-02-14
申请号：US11064592
申请日：2005-02-24
IPC分类号： A61B5/00
CPC分类号： A61M16/0069 , A61M16/024 , A61M2016/0027 , A61M2016/0039 , A61M2230/04
摘要： A method and apparatus that provides an expert system for determining respiratory phase during ventilatory support of a subject. Discrete phase states are partitioned and prior probability functions and observed probability functions for each state are defined. The probability functions are based upon relative duration of each state as well as the flow characteristics of each state. These functions are combined to determine phase probabilities for each state using Bayes' theorem. The calculated probabilities for the states may then be compared to determine which state the subject is experiencing. A ventilator may then conform respiratory support in accordance with the most probable phase. To provide a learning feature, the probability functions may be adjusted during use to provide a more subject specific response that accounts for changing respiratory characteristics.
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公开(公告)号：US07727160B2
公开(公告)日：2010-06-01
申请号：US11287746
申请日：2005-11-28
IPC分类号： A61B5/00
CPC分类号： A61M16/0069 , A61M16/024 , A61M2016/0027 , A61M2016/0039 , A61M2230/04
摘要： A method and apparatus that provides an expert system for determining respiratory phase during ventilatory support of a subject. Discrete phase states are partitioned and prior probability functions and observed probability functions for each state are defined. The probability functions are based upon relative duration of each state as well as the flow characteristics of each state. These functions are combined to determine phase probabilities for each state using Bayes' theorem. The calculated probabilities for the states may then be compared to determine which state the subject is experiencing. A ventilator may then conform respiratory support in accordance with the most probable phase. To provide a learning feature, the probability functions may be adjusted during use to provide a more subject specific response that accounts for changing respiratory characteristics.
摘要翻译： 一种提供用于在受试者的通气支持期间确定呼吸相位的专家系统的方法和装置。 离散相位状态被划分，并且定义了每个状态的先验概率函数和观测概率函数。 概率函数基于每个状态的相对持续时间以及每个状态的流量特性。 这些功能被组合以使用贝叶斯定理确定每个状态的相位概率。 然后可以比较所计算的状态概率，以确定受试者正在经历的状态。 然后呼吸机可以根据最可能的阶段来符合呼吸支持。 为了提供学习特征，在使用期间可以调整概率函数以提供考虑到呼吸特征变化的更多受试者特异性响应。
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公开(公告)号：US07914459B2
公开(公告)日：2011-03-29
申请号：US12765380
申请日：2010-04-22
CPC分类号： A61M16/0069 , A61M16/024 , A61M2016/0027 , A61M2016/0039 , A61M2230/04
摘要： A method and apparatus that provides an expert system for determining respiratory phase during ventilatory support of a subject. Discrete phase states are partitioned and prior probability functions and observed probability functions for each state are defined. The probability functions are based upon relative duration of each state as well as the flow characteristics of each state. These functions are combined to determine phase probabilities for each state using Bayes' theorem. The calculated probabilities for the states may then be compared to determine which state the subject is experiencing. A ventilator may then conform respiratory support in accordance with the most probable phase. To provide a learning feature, the probability functions may be adjusted during use to provide a more subject specific response that accounts for changing respiratory characteristics.
摘要翻译： 一种提供用于在受试者的通气支持期间确定呼吸相位的专家系统的方法和装置。 离散相位状态被划分，并且定义了每个状态的先验概率函数和观测概率函数。 概率函数基于每个状态的相对持续时间以及每个状态的流量特性。 这些功能被组合以使用贝叶斯定理确定每个状态的相位概率。 然后可以比较所计算的状态概率，以确定受试者正在经历的状态。 然后呼吸机可以根据最可能的阶段来符合呼吸支持。 为了提供学习特征，在使用期间可以调整概率函数以提供考虑到呼吸特征变化的更多受试者特异性响应。
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公开(公告)号：US08388548B2
公开(公告)日：2013-03-05
申请号：US13032903
申请日：2011-02-23
IPC分类号： A61B5/08
CPC分类号： A61M16/0069 , A61M16/024 , A61M2016/0027 , A61M2016/0039 , A61M2230/04
摘要： A method and apparatus that provides an expert system for determining respiratory phase during ventilatory support of a subject. Discrete phase states are partitioned and prior probability functions and observed probability functions for each state are defined. The probability functions are based upon relative duration of each state as well as the flow characteristics of each state. These functions are combined to determine phase probabilities for each state using Bayes' theorem. The calculated probabilities for the states may then be compared to determine which state the subject is experiencing. A ventilator may then conform respiratory support in accordance with the most probable phase. To provide a learning feature, the probability functions may be adjusted during use to provide a more subject specific response that accounts for changing respiratory characteristics.
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公开(公告)号：US06860858B2
公开(公告)日：2005-03-01
申请号：US10153343
申请日：2002-05-22
CPC分类号： A61M16/0069 , A61M16/024 , A61M2016/0027 , A61M2016/0039 , A61M2230/04
摘要： A method and apparatus that provides an expert system for determining respiratory phase during ventilatory support of a subject. Discrete phase states are partitioned and prior probability functions and observed probability functions for each state are defined. The probability functions are based upon relative duration of each state as well as the flow characteristics of each state. These functions are combined to determine phase probabilities for each state using Bayes' theorem. The calculated probabilities for the states may then be compared to determine which state the subject is experiencing. A ventilator may then conform respiratory support in accordance with the most probable phase. To provide a learning feature, the probability functions may be adjusted during use to provide a more subject specific response that accounts for changing respiratory characteristics.
摘要翻译： 一种提供用于在受试者的通气支持期间确定呼吸相位的专家系统的方法和装置。 离散相位状态被划分，并且定义了每个状态的先验概率函数和观测概率函数。 概率函数基于每个状态的相对持续时间以及每个状态的流量特性。 这些功能被组合以使用贝叶斯定理确定每个状态的相位概率。 然后可以比较所计算的状态概率，以确定受试者正在经历的状态。 然后呼吸机可以根据最可能的阶段来符合呼吸支持。 为了提供学习特征，在使用期间可以调整概率函数以提供考虑到呼吸特征变化的更多受试者特异性响应。
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公开(公告)号：US20110139156A1
公开(公告)日：2011-06-16
申请号：US13032903
申请日：2011-02-23
IPC分类号： A61M16/00
CPC分类号： A61M16/0069 , A61M16/024 , A61M2016/0027 , A61M2016/0039 , A61M2230/04
摘要： A method and apparatus that provides an expert system for determining respiratory phase during ventilatory support of a subject. Discrete phase states are partitioned and prior probability functions and observed probability functions for each state are defined. The probability functions are based upon relative duration of each state as well as the flow characteristics of each state. These functions are combined to determine phase probabilities for each state using Bayes' theorem. The calculated probabilities for the states may then be compared to determine which state the subject is experiencing. A ventilator may then conform respiratory support in accordance with the most probable phase. To provide a learning feature, the probability functions may be adjusted during use to provide a more subject specific response that accounts for changing respiratory characteristics.
摘要翻译： 一种提供用于在受试者的通气支持期间确定呼吸相位的专家系统的方法和装置。 离散相位状态被划分，并且定义了每个状态的先验概率函数和观测概率函数。 概率函数基于每个状态的相对持续时间以及每个状态的流量特性。 这些功能被组合以使用贝叶斯定理确定每个状态的相位概率。 然后可以比较所计算的状态概率，以确定受试者正在经历的状态。 然后呼吸机可以根据最可能的阶段来符合呼吸支持。 为了提供学习特征，在使用期间可以调整概率函数以提供考虑到呼吸特征变化的更多受试者特异性响应。
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公开(公告)号：US08459260B2
公开(公告)日：2013-06-11
申请号：US13542331
申请日：2012-07-05
申请人： David John Bassin
发明人： David John Bassin
IPC分类号： F16K31/02
CPC分类号： A61M16/0057 , A61M16/0051 , A61M16/024 , A61M16/06 , A61M2016/0021 , A61M2016/003 , A61M2016/0036 , A61M2205/15 , A61M2205/16 , A61M2205/3331 , A61M2205/50
摘要： A respiratory treatment apparatus and method in which a leak is determined by using an averaging window. The window starts at the present time and extends back in time to a point determined according to a current one of progressively detected phase measures of a first respiratory cycle and a corresponding phase measure attributable to a preceding second respiratory cycle. In another aspect, a jamming index indicates whether the leak is rapidly changing. To the extent that jamming is high, the leak estimate used progressively changes from that using sliding breath-window averaging to a more robust and faster responding low-pass filter method, and adjustment of ventilatory support based on measures employing estimated respiratory flow is slowed down or stopped.
摘要翻译： 一种呼吸治疗装置和方法，其中通过使用平均窗来确定泄漏。 该窗口从当前开始，并且在时间上延伸到根据第一呼吸周期的逐渐检测的相位测量值和归因于之前的第二呼吸周期的相应相位测量值中的当前测量值确定的点。 另一方面，干扰指数指示泄漏是否迅速变化。 在干扰程度较大的情况下，泄漏估算值从使用滑动呼吸窗口平均值到更健壮，更快速响应的低通滤波方法逐渐变化，基于使用估计呼吸流量的措施调节呼吸支持减慢 或停止。
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公开(公告)号：US08448640B2
公开(公告)日：2013-05-28
申请号：US13242752
申请日：2011-09-23
申请人： David John Bassin
发明人： David John Bassin
IPC分类号： A61M16/00
CPC分类号： A61M16/0069 , A61M16/00 , A61M16/0003 , A61M16/0066 , A61M16/024 , A61M16/04 , A61M16/06 , A61M16/0875 , A61M16/20 , A61M2205/3334 , A61M2205/50 , A61M2205/502 , A61M2230/005 , A61M2230/40
摘要： A ventilator device delivers ventilatory support to a patient in a back up timed mode when patient respiration is not detected or a spontaneous mode when patient respiration is detected. The timing threshold governing the back-up mode is chosen to deviate from normal expected respiration time for the patient to promote patient initiated ventilation in the spontaneous mode but permit back-up ventilation in the event of apnea. Automated adjustments to the timing threshold during the timed mode are made from the less vigilant timing threshold to a more vigilant threshold at or near a timing of normal expected breathing of the patient. Such adjustments may be made from a minimum to a maximum vigilance timing settings or incrementally there between as a function of time in the timed mode which is preferably the number of delivered machine breaths.
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公开(公告)号：US08356594B2
公开(公告)日：2013-01-22
申请号：US12613035
申请日：2009-11-05
申请人： Anthony John Ujhazy , Jonathan Caldwell Wright , Glenn Richards , David John Bassin , Michael Berthon-Jones
发明人： Anthony John Ujhazy , Jonathan Caldwell Wright , Glenn Richards , David John Bassin , Michael Berthon-Jones
IPC分类号： A62B9/00
CPC分类号： A61B5/4836 , A61B5/0826 , A61B5/087 , A61B5/7282 , A61B5/746 , A61M16/0051 , A61M16/0057 , A61M16/0066 , A61M16/0069 , A61M16/024 , A61M16/06 , A61M2016/0021 , A61M2016/0036 , A61M2205/3344 , A61M2230/005 , A61M2230/04 , A61M2230/10 , A61M2230/18 , A61M2230/40 , A61M2230/435 , A61M2230/63
摘要： Methods and apparatus for assessing the condition of and treating patients for heart failure by the delivery of continuous positive airway pressure are disclosed. Treatment of obstruction due to reflex vocal cord closure often experienced by heart failure patients is distinguished from treatment of upper airway obstruction typically associated with Obstructive Sleep Disorder Treatment may also be implemented by delivering synchronized cardiac pressure oscillations superimposed on a respiratory pressure level to provide assistance for the heart. Heart treatment pressure dose indicator may be calculated for prescribing and monitoring the delivery of treatment. The apparatus may also generate data to track heart failure condition that may be indicative of the degree of severity of heart failure based upon breathing patterns to assist in the diagnosis and management of heart failure patients.
摘要翻译： 公开了通过递送持续气道正压通气来评估患者心力衰竭状况和治疗方法和装置。 治疗由于心力衰竭患者经常发生的反射性声带闭合引起的阻塞与区别于通常与阻塞性睡眠障碍相关的上呼吸道阻塞治疗也可以通过递送叠加在呼吸压力水平上的同步心脏压力振荡来实现，以便为 心脏 可以计算心脏治疗压力剂量指标，用于处方和监测治疗的递送。 该装置还可以生成跟踪心力衰竭状况的数据，该状况可以基于呼吸模式来指示心力衰竭的严重程度，以帮助心力衰竭患者的诊断和管理。
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