公开(公告)号：US20170298009A1

公开(公告)日：2017-10-19

申请号：US15516352

申请日：2015-10-01

Applicant: PURAC BIOCHEM BV

Inventor： Bastiaan Jeroen Victor VERKUIJL ,  Jurgen Cornelis Henricus MAAS

IPC: C07C235/06 ,  C07C231/02 ,  C07C231/16 ,  C07C231/24

CPC classification number: C07C235/06 ,  C07C231/02 ,  C07C231/16 ,  C07C231/24

Abstract: A method for the manufacture of N,N-dialkyllactamide, whereby at least one of the compounds selected from the series made of alkyl lactate, lactide and polylactic acid is mixed with dialkylamine in order to form a reaction mixture, under conditions whereby aminolysis takes place in the reaction mixture. The method is characterized in that the reaction mixture further includes a Lewis acid. As a result of the method, N,N-dialkyllactamides can be manufactured in high yields and with high optical purity.

公开(公告)号：US20170349525A1

公开(公告)日：2017-12-07

申请号：US15537698

申请日：2015-12-22

Applicant: PURAC BIOCHEM BV

Inventor： Bastiaan Jeroen Victor VERKUIJL ,  Andre Banier DE HAAN

IPC: C07C51/48 ,  C07C53/126 ,  C07C67/58 ,  C07C69/24

CPC classification number: C07C51/48 ,  C07C53/126 ,  C07C67/58 ,  C07C69/24

Abstract: A method for separation of fatty acid from a mixture having fatty acid, the corresponding acyl lactylate and lactic acid, method having steps of: a) providing dispersion of mixture in polar carrier; b) adjusting dispersion mixture to pH from 5-9; and, c) extracting fatty acid from dispersion carrier mixture into solvent immiscible with polar carrier, obtaining fatty acid solution and aqueous raffinate having lactic acid and fatty acid lactylate. Polar carrier has from 70-100 wt. % of water and from 0-30 wt. % of one or more miscible, polar co-solvents. Aqueous raffinate may be further processed by: i) acidifying raffinate to pH from 0-3; and, either ii)a) allowing acidified raffinate to separate into two layers and separating lower, aqueous layer from residual layer of acyl lactylate, or ii)b) extracting fatty acid lactylate from acidified raffinate into second solvent which is immiscible with aqueous raffinate, obtaining an acyl lactylate solution.