公开(公告)号：US20250051829A1

公开(公告)日：2025-02-13

申请号：US18717794

申请日：2022-12-08

Applicant: POSTECH Research and Business Development Foundation

Inventor： Chang Ha WOO ,  Jeong Wook LEE ,  Jeongmin LEE ,  Doeon SUNG

IPC: C12Q1/6816 ,  C12Q1/6888

Abstract: The present invention relates to a method for generating a single-stranded region for detecting genetic mutation and a method for detecting genetic mutation using same. A detection method according to the present invention can detect sequence-specific nucleic acids and detect mutations at the single nucleotide polymorphism (SNP) discrimination level, thereby allowing for the accurate and sensitive discrimination of mutations in a short time. Thus, the present invention provides an effective mutation detection method that can respond not only to current SARS-CoV-2 variants but also generally to specific diseases or related mutations in the future.