公开(公告)号：US3770733A

公开(公告)日：1973-11-06

申请号：US3770733D

申请日：1971-08-30

Applicant: PHARMAC CO RECORDATI SA CHEM C

Inventor： SETNIKAR I ,  MASSARANI E ,  SIANESI E ,  DA RE P

IPC: C07C309/59 ,  C07C309/89 ,  C07C311/16 ,  C07D279/02 ,  C07D93/02

CPC classification number: C07D279/02 ,  C07C309/59 ,  C07C309/89 ,  C07C311/16

Abstract: -N(-R1)-R2

WHEREIN X REPRESENTS A STRAIGHT OR BRANCHED CHAIN ALKYLENE GROUP HAVING 1 TO 3 CARBON ATOMS, AND R REPRESENTS A GROUP HAVING THE FORMULA

1,1-DI(O=),2-(R-CO-X-)-3,4-DIHYDRO-2H-1,2-BENZOTHIAZINE

NEW, THERAPEUTICALLY ACTIVE COMPOUNDS HAVING THE FORMULA
WHEREIN R3 AND R4, WHICH ARE THE SAME OR DIFFERENT, EACH REPRESENTS HYDROGEN OR A LOWER ALKYL GROUP, OR A PHENYL GROUP, OR TOGETHER FORM AN ALKYLIDENE GROUP HAVING 2 OR 3 CARBON ATOMS, AND PROCESSES FOR PREPARING THE SAID COMPOUNDS.

-NH-N(-R3)-R4

WHEREIN R1 AND R2, WHICH ARE THE SAME OR DIFFERENT, EACH REPRESENTS HYDROGEN OR A STRAIGHT OR BRANCHED CHAIN ALKYL, ALKENYL OR ALKYNYL GROUP HAVING UP TO 4 CARBON ATOMS, OR A PHENYL GROUP, OR R1 AND R2 TOGETHER WITH THE NITROGEN ATOM TO WHICH THEY ARE BONDED FORM A MORPHOLINO, PIPERIDINO, PYRROLIDINO OR 4-METHYL-PIPERIZINO GROUP, OR R REPRESENTS A GROUP HAVING THE FORMULA