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    Regenerable affinity sensors and associated methods
    2.
    发明授权
    Regenerable affinity sensors and associated methods 有权

    公开(公告)号：US12181470B2

    公开(公告)日：2024-12-31

    申请号：US17481806

    申请日：2021-09-22

    Applicant: Palo Alto Research Center Incorporated

    Inventor： Sean Doris ,  Anne Plochowietz ,  Jerome Unidad

    IPC: G01N33/543

    Abstract: Affinity sensors may exhibit advantaged regeneration behavior when pH is changed in proximity to a sensing element. Such affinity sensors may comprise at least one sensing element comprising a recognition moiety that interacts with an analyte by reversibly forming an analyte complex, and a solid-state pH-modulating element in proximity to the at least one sensing element, wherein formation of the analyte complex is pH-dependent and the at least one sensing element provides a signal that changes when the analyte complex reversibly forms, and a change in magnitude of the signal is correlatable to an amount of analyte interacted with the at least one sensing element.

    SYSTEM AND METHOD TO SEPARATE GASES USING HIGH VISCOSITY LIQUID SORBENTS IN A SPRAY CONTACTOR
    4.
    发明申请
    SYSTEM AND METHOD TO SEPARATE GASES USING HIGH VISCOSITY LIQUID SORBENTS IN A SPRAY CONTACTOR 有权

    公开(公告)号：US20230130161A1

    公开(公告)日：2023-04-27

    申请号：US17509816

    申请日：2021-10-25

    Applicant: PALO ALTO RESEARCH CENTER INCORPORATED

    Inventor： Mahati Chintapalli ,  Jerome Unidad ,  Kathryn F. Murphy ,  Ravi Neelakantan ,  Rahul Pandey ,  Stephen Matthew Meckler ,  David Mathew Johnson

    IPC: B01D53/14

    Abstract: A gas separation system has system input inlet configured to receive a stream mixture including a target gas, one or more spray generators positioned to spray a non-sprayable liquid to change a concentration of the target gas in the non-sprayable liquid, one or more system outlets positioned to outlet an output material, wherein at least one of the system outlets outputs a material having a lower amount of the target gas than the input stream mixture, and a recirculating path connected to the one or more outputs and the input inlet to allow recirculation of the non-sprayable liquid. A method of performing gas separation includes absorbing a target gas from an input stream in a non-sprayable capture liquid, and releasing the target gas in an output gas stream by spraying the non-sprayable capture liquid into a heated volume using a spray generator. A method of performing gas separation includes receiving an input stream that includes a target gas, using one or more spray generators to apply a non-sprayable liquid as a spray to the input stream to change a concentration of the target gas in the liquid, and outputting the liquid with the changed concentration through an outlet.

    Exabyte-scale data storage using sequence-controlled polymers
    6.
    发明授权
    Exabyte-scale data storage using sequence-controlled polymers 有权

    公开(公告)号：US11249941B2

    公开(公告)日：2022-02-15

    申请号：US16229306

    申请日：2018-12-21

    Applicant: PALO ALTO RESEARCH CENTER INCORPORATED

    Inventor： Jerome Unidad ,  David Mathew Johnson ,  Elif Karatay ,  Mahati Chintapalli

    IPC: G06F16/11 ,  G01N21/64 ,  B41M3/00 ,  G01N33/44

    Abstract: A method of storing digital data in non-biological sequence-controlled polymers includes converting a digital data file into a monomer sequence, synthesizing polymer chains according to the monomer sequence, and encapsulating the polymer chains into microfluidic droplets and providing the microfluidic droplets with addresses. A polymer data storage system has a first converter to convert digital data to a polymer sequence, a polymer synthesizer to produce polymer chains according to a pre-determined monomer sequence, a fluidic encapsulation system to encapsulate the polymer chains in microfluidic droplets and to apply addressing materials to the microfluidic droplets, a storage for storing the microfluidic droplets, a droplet sorting system having at least an actuator to sort the droplets, a sequencer to derive the polymer sequence from the polymer chains contained in the droplets, and a second converter to convert the polymer sequence to digital data. A composition of matter wherein polymer chains comprising alternating segments of flexible linkers and one or more rigid monomer blocks, and wherein the rigid blocks are defined in a meaningful manner to store in a sequence in the polymer chain that represents digital data.

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