公开(公告)号：US10588893B2

公开(公告)日：2020-03-17

申请号：US16064618

申请日：2016-12-27

Applicant: OTSUKA PHARMACEUTICAL CO., LTD.

Inventor： Yoshihiro Murakami ,  Hitoshi Matsushita ,  Kengo Matsumoto ,  Minoru Okada ,  Yohei Yuki ,  Noriyuki Koyama ,  Naohiko Kanai

IPC: A61K31/421 ,  A61K9/06 ,  A61K47/44 ,  A61P17/04 ,  C07D263/32

Abstract: An ointment is provided. The ointment stably comprises an oxazole compound that has specific inhibitory activity against PDE4 and that is represented by the following formula (11). The ointment can be efficiently absorbed into the skin.