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公开(公告)号：US20220145386A1
公开(公告)日：2022-05-12
申请号：US17585814
申请日：2022-01-27
IPC分类号： C12Q1/6869 , C12Q1/6844
摘要： The present invention relates to methods and kits for the detection of 5-hydroxymethylcytosine (5hmC) and/or 5-methylcytosine (5meC). In some embodiments, the present invention relates to methods and kits for detection of 5hmC and/or 5meC in nucleic acid (e.g., DNA, RNA). In some embodiments, the present invention relates to detection of 5hmC in genomic DNA, e.g., mammalian genomic DNA
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公开(公告)号：US10023909B2
公开(公告)日：2018-07-17
申请号：US14363442
申请日：2012-12-13
IPC分类号： C12Q1/6869 , C12Q1/6844
摘要： The present invention relates to methods and kits for the detection of 5-hydroxymethylcytosine (5hmC) and/or 5-methylcytosine (5meC). In some embodiments, the present invention relates to methods and kits for detection of 5hmC and/or 5meC in nucleic acid (e.g., DNA, RNA). In some embodiments, the present invention relates to detection of 5hmC in genomic DNA, e.g., mammalian genomic DNA.
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公开(公告)号：US20140363815A1
公开(公告)日：2014-12-11
申请号：US14363442
申请日：2012-12-13
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6869 , C12Q1/6846 , C12Q2523/125 , C12Q2531/113 , C12Q2521/125
摘要： The present invention relates to methods and kits for the detection of 5-hydroxymethylcytosine (5hmC) and/or 5-methylcytosine (5meC). In some embodiments, the present invention relates to methods and kits for detection of 5hmC and/or 5meC in nucleic acid (e.g., DNA, RNA). In some embodiments, the present invention relates to detection of 5hmC in genomic DNA, e.g., mammalian genomic DNA
摘要翻译： 本发明涉及用于检测5-羟甲基胞嘧啶（5hmC）和/或5-甲基胞嘧啶（5meC）的方法和试剂盒。 在一些实施方案中，本发明涉及用于检测核酸（例如DNA，RNA）中的5meC和/或5meC的方法和试剂盒。 在一些实施方案中，本发明涉及在基因组DNA例如哺乳动物基因组DNA中检测5hmC
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公开(公告)号：US20210285961A1
公开(公告)日：2021-09-16
申请号：US16328909
申请日：2017-08-29
发明人： John Arne Dahl , Arne Klungland
IPC分类号： G01N33/68 , C12Q1/6804 , C12N15/10
摘要： In some embodiments, the present invention provides chromatin immunoprecipitation (ChIP) methods. In particular, the present invention provides methods and compositions for performing ChIP (e.g., ChlP-seq) assays on small numbers or cells.
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公开(公告)号：US11543417B2
公开(公告)日：2023-01-03
申请号：US16328909
申请日：2017-08-29
发明人： John Arne Dahl , Arne Klungland
IPC分类号： C12N15/10 , C12Q1/6804 , G01N33/68
摘要： In some embodiments, the present invention provides chromatin immunoprecipitation (ChIP) methods. In particular, the present invention provides methods and compositions for performing ChIP (e.g., ChlP-seq) assays on small numbers or cells.
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公开(公告)号：US11078529B2
公开(公告)日：2021-08-03
申请号：US16009835
申请日：2018-06-15
IPC分类号： C12Q1/6869 , C12Q1/6844
摘要： The present invention relates to methods and kits for the detection of 5-hydroxymethylcytosine (5hmC) and/or 5-methylcytosine (5meC). In some embodiments, the present invention relates to methods and kits for detection of 5hmC and/or 5meC in nucleic acid (e.g., DNA, RNA). In some embodiments, the present invention relates to detection of 5hmC in genomic DNA, e.g., mammalian genomic DNA.
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公开(公告)号：US20180291442A1
公开(公告)日：2018-10-11
申请号：US16009835
申请日：2018-06-15
IPC分类号： C12Q1/6869 , C12Q1/6844
摘要： The present invention relates to methods and kits for the detection of 5-hydroxymethylcytosine (5hmC) and/or 5-methylcytosine (5meC). In some embodiments, the present invention relates to methods and kits for detection of 5hmC and/or 5meC in nucleic acid (e.g., DNA, RNA). In some embodiments, the present invention relates to detection of 5hmC in genomic DNA, e.g., mammalian genomic DNA
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公开(公告)号：US20170283863A1
公开(公告)日：2017-10-05
申请号：US15620209
申请日：2017-06-12
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6827 , C12Q1/6806 , Y10T436/147777 , C12Q2563/149 , C12Q2537/164 , C12Q2521/531 , C12Q2522/10
摘要： The present invention relates to methods and kits for the detection of 5-hydroxymethylcytosine (5hmC). In some embodiments, the present invention relates to methods and kits for detection of 5hmC in nucleic acid (e.g., DNA, RNA). In some embodiments, the present invention relates to detection of 5hmC in genomic DNA, e.g., mammalian genomic DNA.
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