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公开(公告)号:US20220089979A1
公开(公告)日:2022-03-24
申请号:US17343376
申请日:2021-06-09
申请人: Novozymes A/S
发明人: Jens Erik Nielsen , Lars Anderson , Allan Svendsen , Rune Nygaard Monrad , Lars Giger , Vasudeva Prahlada Rao , Sohel Dalal , Santhosh Vasu Mepadam , Marie Thrysoe Kruse , Kasper D. Rand , Pernille F. Jensen
摘要: The present invention relates to endoglucanase variants and methods for obtaining endoglucanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号:US11525128B2
公开(公告)日:2022-12-13
申请号:US16636550
申请日:2018-08-03
申请人: Novozymes A/S
发明人: Rune Nygaard Monrad , Vasudeva Prahlada Rao , Rajendra Kulothungan Sainathan , Sohel Dalal , VSanthosh Vasu Mepadam , Allan Svendsen , Mette Louise Dissing Overgaard , Lars Andersen , Geetha Hiremath Mendez
IPC分类号: C12N9/42
摘要: The present invention relates to endoglucanase variants and methods for obtaining endoglucanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号:US20210155916A1
公开(公告)日:2021-05-27
申请号:US16636550
申请日:2018-08-03
申请人: Novozymes A/S
发明人: Rune Nygaard Monrad , Vasudeva Prahlada Rao , Rajendra Kulothungan Sainathan , Sohel Dalal , VSanthosh Vasu Mepadam , Allan Svendsen , Mette Louise Dissing Overgaard , Lars Andersen , Geetha Hiremath Mendez
IPC分类号: C12N9/42
摘要: The present invention relates to endoglucanase variants and methods for obtaining endoglucanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号:US11072765B2
公开(公告)日:2021-07-27
申请号:US16327376
申请日:2017-08-24
申请人: NOVOZYMES A/S
发明人: Jens Erik Nielsen , Lars Anderson , Allan Svendsen , Rune Nygaard Monrad , Lars Giger , Vasudeva Prahlada Rao , Sohel Dalal , Santhosh Vasu Mepadam , Marie Thrysoe Kruse , Kasper D. Rand , Pernille F. Jensen
摘要: The present invention relates to endoglucanase variants and methods for obtaining endoglucanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号:US20190218478A1
公开(公告)日:2019-07-18
申请号:US16327376
申请日:2017-08-24
申请人: NOVOZYMES A/S
发明人: Jens Erik Nielsen , Lars Anderson , Allan Svendsen , Rune Nygaard Monrad , Lars Giger , Vasudeva Prahlada Rao , Sohel Dalal , Santhosh Vasu Mepadam , Marie Thrysoe Kruse , Kasper D. Rand , Pernille F. Jensen
CPC分类号: C11D3/38645 , C11D3/38636 , C12N9/2437 , C12Y302/01004
摘要: The present invention relates to endoglucanase variants and methods for obtaining endoglucanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号:US11795418B2
公开(公告)日:2023-10-24
申请号:US17343376
申请日:2021-06-09
申请人: Novozymes A/S
发明人: Jens Erik Nielsen , Lars Anderson , Allan Svendsen , Rune Nygaard Monrad , Lars Giger , Vasudeva Prahlada Rao , Sohel Dalal , Santhosh Vasu Mepadam , Marie Thrysoe Kruse , Kasper D. Rand , Pernille F. Jensen
CPC分类号: C11D3/38645 , C11D3/38636 , C12N9/2437 , C12Y302/01004
摘要: The present invention relates to endoglucanase variants and methods for obtaining endoglucanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号:US11326153B2
公开(公告)日:2022-05-10
申请号:US16770797
申请日:2018-12-07
申请人: NOVOZYMES A/S
发明人: Carsten Andersen , Vasudeva Prahlada Rao , Rakhi Saikia , Vivek Srivastava , Kendra Darlene Stallings
摘要: The present invention relates to alpha-amylase variants comprising a substitution at a position corresponding to position 188 and at least one further substitution at a position corresponding to position 242 or 279 or 275 of SEQ ID NO: 1, in particular one or more combinations of substitutions selected from the group consisting of E188P+S242Y, E188P+S242F, E188P+S242H, E188P+S242W, E188P+S242P, E188P+S242I, E188P+S242T, E188P+S242L, E188P+K279W, E188P+K279Y, E188P+K279F, E188P+K279H, E188P+K279I, E188P+K279L, E188P+K279D, E188P+K279M, E188P+K279S, E188P+K279T E188P+K279N, E188P+K279Q, E188P+K279V, E188P+K279A, E188P+N275F, E188P+N275Y, E188P+N275W, and E188P+N275H, wherein the variant has at least 60%, at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100% sequence identity to a parent alpha amylase selected from the group consisting of: SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 15, SEQ ID NO: 16, SEQ ID NO: 17, SEQ ID NO: 18, and SEQ ID NO: 27. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号:US11359188B2
公开(公告)日:2022-06-14
申请号:US16636549
申请日:2018-08-03
申请人: Novozymes A/S
发明人: Rune Nygaard Monrad , Rajendra Kulothungan Sainathan , Geetha Hiremath Mendez , Sohel Dalal , Shilpi Agarwal , Allan Svendsen , Mette Louise Dissing Overgaard , Vasudeva Prahlada Rao
摘要: The present invention relates to xanthan lyase variants and methods for obtaining xanthan lyase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号:US11203790B2
公开(公告)日:2021-12-21
申请号:US16656708
申请日:2019-10-18
申请人: NOVOZYMES A/S
发明人: Shikha Gupta , Allan Svendsen , Vivek Srivastava , Marco Malten , Thomas Agersten Poulsen , Preethi Ramaiya , Beth Nelson , Vasudeva Prahlada Rao , Padmavathi Balumuri
摘要: The present invention relates to glucoamylase variants, polynucleotides encoding the variants, methods of producing the variants, and methods of using the variants. Also described are the use of glucoamylases of the invention for starch conversion to produce fermentation products, such as ethanol, and syrups, such as glucose. The invention also relates to a composition comprising a glucoamylase variant of the invention.
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公开(公告)号:US20210189364A1
公开(公告)日:2021-06-24
申请号:US16770797
申请日:2018-12-07
申请人: NOVOZYMES A/S
发明人: Carsten Andersen , Vasudeva Prahlada Rao , Rakhi Saikia , Vivek Srivastava , Kendra Darlene Stallings
摘要: The present invention relates to alpha-amylase variants comprising a substitution at a position corresponding to position 188 and at least one further substitution at a position corresponding to position 242 or 279 or 275 of SEQ ID NO: 1, in particular one or more combinations of substitutions selected from the group consisting of E188P+S242Y, E188P+S242F, E188P+S242H, E188P+S242W, E188P+S242P, E188P+S242I, E188P+S242T, E188P+S242L, E188P+K279W, E188P+K279Y, E188P+K279F, E188P+K279H, E188P+K279I, E188P+K279L, E188P+K279D, E188P+K279M, E188P+K279S, E188P+K279T E188P+K279N, E188P+K279Q, E188P+K279V, E188P+K279A, E188P+N275F, E188P+N275Y, E188P+N275W, and E188P+N275H, wherein the variant has at least 60%, at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100% sequence identity to a parent alpha amylase selected from the group consisting of: SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 15, SEQ ID NO: 16, SEQ ID NO: 17, SEQ ID NO: 18, and SEQ ID NO: 27. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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