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公开(公告)号:US11851659B2
公开(公告)日:2023-12-26
申请号:US16498361
申请日:2018-03-21
发明人: Jennifer Brogdon , Ming-Wei Chen , Hyungwook Lim , Yi Yang , Morag Stewart , Sarah Hesse
IPC分类号: C12N9/22 , C12N15/86 , C12N15/113 , A61K35/17 , C07K14/705
CPC分类号: C12N15/1138 , A61K35/17 , C07K14/70503 , C07K14/70578 , C12N9/22 , C12N15/86 , C07K2319/30 , C07K2319/33 , C12N2310/20 , C12N2750/14143 , C12N2800/80
摘要: The present disclosure is directed to genome editing systems, reagents and methods for immunooncology.
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公开(公告)号:US20220364055A1
公开(公告)日:2022-11-17
申请号:US17271430
申请日:2019-08-30
申请人: Novartis AG
发明人: Louise Treanor , Michael R. Greene , Jennifer Brogdon , Boris Engels , Glenn Dranoff , Olja Kodrasi , Hyungwook Lim , Akash Sohoni , Elizabeth Dorothy Pratico , Anniesha Hack , Aida Abujoub , Tony Fleming , Lu Huang , Connie Hong , John Blankenship , Brian Holmberg , Chonghui Zhang , Dexiu Bu , Andrew Price , Xu Zhu , Andrew Stein , Attilio Bondanza
IPC分类号: C12N5/0783 , A61K35/17 , A61K31/519 , A61K38/20 , C07K16/28 , C07K14/705
摘要: The invention provides methods of making immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions generated by such methods.
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公开(公告)号:US20210220404A1
公开(公告)日:2021-07-22
申请号:US17104983
申请日:2020-11-25
申请人: Michael R. Greene , Novartis AG
发明人: Aida Abujoub , John Blankenship , Attilio Bondanza , Jennifer Brogdon , Dexiu Bu , Serena De Vita , Glenn Dranoff , Boris Engels , Tony Fleming , Brian Walter Granda , Michael R. Greene , Carla Patricia Guimaraes , Anniesha Hack , Brian Holmberg , Connie Hong , Lu Huang , Olja Kodrasi , Joni Waiee Lam , Hyungwook Lim , Elizabeth Dorothy Pratico , Andrew Price , Akash Sohoni , Andrew Marc Stein , Louise Treanor , Chonghui Zhang , Xu Zhu
IPC分类号: A61K35/17 , C07K16/28 , A61P35/00 , A61K45/06 , A61K39/395 , C07K14/705 , A61K38/17 , C12N5/0783 , C07K14/725
摘要: The invention provides immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions and methods thereof.
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