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公开(公告)号：US20230339879A1
公开(公告)日：2023-10-26
申请号：US18187380
申请日：2023-03-21
IPC分类号： C07D311/58 , C07D311/64 , C07D311/92 , C07D215/14 , C07D307/80 , C07C67/303
CPC分类号： C07D311/58 , C07C67/303 , C07D215/14 , C07D307/80 , C07D311/64 , C07D311/92
摘要： Disclosed are chromane compounds, analogs thereof, and methods of their synthesis and use. The compounds may be synthesized by methods involving reductive annulations of arylidene malonates with unsaturated electrophiles using photoredox/Lewis acid cooperative catalysis. The compounds may be formulated in a pharmaceutical composition for treating one of the aforementioned diseases or disorders.
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公开(公告)号：US11639340B2
公开(公告)日：2023-05-02
申请号：US16923843
申请日：2020-07-08
IPC分类号： C07D311/58 , C07D215/14 , C07D215/58 , C07D307/80 , C07D311/92
摘要： Disclosed are chromane compounds, analogs thereof, and methods of their synthesis and use. The compounds may be synthesized by methods involving reductive annulations of arylidene malonates with unsaturated electrophiles using photoredox/Lewis acid cooperative catalysis. The compounds may be formulated in a pharmaceutical composition for treating one of the aforementioned diseases or disorders.
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公开(公告)号：US20210009547A1
公开(公告)日：2021-01-14
申请号：US16923843
申请日：2020-07-08
IPC分类号： C07D311/58 , C07D311/92 , C07D215/58 , C07D215/14 , C07D307/80
摘要： Disclosed are chromane compounds, analogs thereof, and methods of their synthesis and use. The compounds may be synthesized by methods involving reductive annulations of arylidene malonates with unsaturated electrophiles using photoredox/Lewis acid cooperative catalysis. The compounds may be formulated in a pharmaceutical composition for treating one of the aforementioned diseases or disorders.
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