公开(公告)号：US10360472B2

公开(公告)日：2019-07-23

申请号：US15156250

申请日：2016-05-16

申请人： New York University ,  Albert-Ludwigs-Universität Freiburg

发明人： Dmitry Novikov ,  Ileana Jelescu ,  Jelle Veraart ,  Els Fieremans ,  Valerij Kiselev ,  Marco Reisert

IPC分类号： G06K9/00 ,  G06K9/52 ,  A61B5/055 ,  G01R33/56 ,  A61B5/00 ,  G01R33/563

摘要： An exemplary system, method and computer-accessible medium for determining a plurality of tissue parameters of a tissue(s), can include, for example, receiving information related to a plurality of rotational invariants contained within a diffusion magnetic resonance (dMR) image(s) of the tissue(s), and generating the tissue parameters using a set of rotational invariants related to the plurality of tissue parameters using such information. The tissue parameters can be generated by factorizing a response of an individual fiber segment of the tissue(s) based on the set of rotational invariants. The response of the individual fiber segments can be factorized from an orientational distribution function (“ODF”). The individual fiber segments can be factorized using a scalar tensor factorization(s) of the rotational invariants. The set of rotational invariants can be of a rotation group SO(3).

公开(公告)号：US10849528B2

公开(公告)日：2020-12-01

申请号：US15574474

申请日：2016-05-16

申请人： New York University ,  Albert-Ludwigs-Universitat Freiburg

发明人： Dmitry Novikov ,  Jerian Jahani ,  Valeriji G. Kiselev

IPC分类号： A61B5/055 ,  A61B5/0275 ,  G01R33/563 ,  A61B5/00 ,  A61B5/026 ,  A61B8/06 ,  A61B5/029

摘要： An exemplary system, method and computer-accessible medium for determining an arterial input function (AIF) of a mammal(s) can be provided, which can include, for example, receiving information related to a global circulatory system of the mammal(s), and determining the AIF based on the information by modeling a blood flow in the global circulatory system of the mammal(s) in terms of an input response function(s). The input response function(s) can include a delayed input response function(s). In certain exemplary embodiments of the present disclosure, the input response function(s) can include at least three input response functions, and each of the input response functions can be from a different part of a body of the mammal(s). The AIF can be determined by coupling the input response functions. The AIF can be further determined based on a total tracer amount in an organ(s) of the mammal(s).

公开(公告)号：US10698065B2

公开(公告)日：2020-06-30

申请号：US15574467

申请日：2016-05-16

申请人： New York University ,  University of Antwerp

发明人： Dmitry Novikov ,  Jelle Veraart ,  Els Fieremans

IPC分类号： A61B5/055 ,  G01R33/563 ,  A61B5/00 ,  G01R33/565 ,  G06K9/40 ,  G06K9/62 ,  G06T7/00

摘要： An exemplary system, method and computer-accessible medium for removing noise and Gibbs ringing from a magnetic resonance (“MR”) image(s), can be provided, which can include, for example, receiving information related to the MR image(s), receiving information related to the MR image(s), and removing the Gibbs ringing from the information by extrapolating data in a k-space from the MR image(s) beyond an edge(s) of a measured portion of the k-space. The data can be extrapolated by formatting the data as a regularized minimization problem(s). A first weighted term of the regularized minimization problem(s) can preserve a fidelity of the extrapolated data, and a second weighted term of the regularized minimization problem(s) can be a penalty term that can be based a norm(s) of the MR image(s), which can be presumed to be sparse.

公开(公告)号：US11366190B2

公开(公告)日：2022-06-21

申请号：US17109023

申请日：2020-12-01

申请人： New York University

发明人： Dmitry Novikov ,  Els Fieremans ,  Gregory Lemberskiy

IPC分类号： A61B5/05 ,  G01R33/563 ,  A61B5/055 ,  A61B5/00 ,  G01R33/50 ,  G01R33/561 ,  G01R33/565

摘要： An exemplary system, method and computer-accessible medium for characterizing a microstructure of a prostate of a patient can be provided, which can include, for example, generating a magnetic resonance (MR) radiofrequency (RF) pulse(s) by varying (i) a diffusion time, (ii) a diffusion gradient direction, (iii) a diffusion gradient pulse width, or (iv) a diffusion gradient pulse shape, applying the MR RF pulse(s) to the prostate of the patient, receiving a resultant MR signal from the prostate of the patient that can be based on the MR RF pulse(s), determining information regarding a plurality of compartments for the prostate from the resultant MR signal by varying an echo time or a mixing time, and characterizing the microstructure for each of the compartments by applying a microstructural model(s) to each of the compartments.

公开(公告)号：US20180120404A1

公开(公告)日：2018-05-03

申请号：US15574467

申请日：2016-05-16

申请人： New York University ,  University of Antwerp

发明人： Dmitry Novikov ,  JELLE VERAART ,  ELS FIEREMANS

IPC分类号： G01R33/565 ,  A61B5/00 ,  G01R33/563 ,  G06K9/40 ,  G06T7/00 ,  A61B5/055

摘要： An exemplary system, method and computer-accessible medium for removing noise and Gibbs ringing from a magnetic resonance (“MR”) image(s), can be provided, which can include, for example, receiving information related to the MR image(s), receiving information related to the MR image(s), and removing the Gibbs ringing from the information by extrapolating data in a k-space from the MR image(s) beyond an edge(s) of a measured portion of the k-space. The data can be extrapolated by formatting the data as a regularized minimization problem(s). A first weighted term of the regularized minimization problem(s) can preserve a fidelity of the extrapolated data, and a second weighted term of the regularized minimization problem(s) can be a penalty term that can be based a norm(s) of the MR image(s), which can be presumed to be sparse

公开(公告)号：US11529069B2

公开(公告)日：2022-12-20

申请号：US17109050

申请日：2020-12-01

申请人： New York University

发明人： Dmitry Novikov ,  Gregory Lemberskiy ,  Steven H. Baete ,  Jelle Veraart ,  Els Fieremans

IPC分类号： A61B5/00 ,  A61B5/055 ,  G01R33/385 ,  G01R33/48 ,  G01R33/563

摘要： An exemplary system, method and computer-accessible medium for generating a denoised magnetic resonance (MR) image(s) of a portion(s) of a patient(s) can be provided, which can include, for example, generating a plurality of MR images of the portion(s), where a number of the MR images can be based on a number of MR coils in a MR apparatus used to generate the MR images, generating MR imaging information by denoising a first one of the MR images based on another one of the MR images, and generating the denoised MR image(s) based on the MR imaging information. The number of the MR coils can be a subset of a total number of the MR coils in the MR apparatus. The number of the MR coils can be a total number of the MR coils in the MR apparatus. The MR information can be generated by denoising each of the MR images based on the other one of the MR images.