公开(公告)号：US20220235056A1

公开(公告)日：2022-07-28

申请号：US17608582

申请日：2020-05-01

申请人： Nektar Therapeutics

发明人： Neel K. Anand ,  Natalia Aurrecoechea ,  Anthony James Brockway ,  Haiying Cai ,  Lin Cheng ,  Bo-Liang Deng ,  Donogh John Roger O'Mahony ,  Zhongxu Ren ,  Wen Zhang

IPC分类号： C07D487/04 ,  C07D519/00

摘要： The instant disclosure provides novel adenosine receptor antagonist compounds, compositions, methods of making and methods of using. In a further aspect, a method of treating a subject in need thereof, comprising administering a therapeutically effective amount of any one or more of the compounds described herein. In some embodiments, the subject has cancer and the method is a method of treating cancer.