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公开(公告)号：US20240108572A1
公开(公告)日：2024-04-04
申请号：US18538438
申请日：2023-12-13
IPC分类号： A61K9/00 , A61F2/02 , A61K31/337 , A61K31/397 , A61K31/436 , A61K31/65 , A61K31/7036 , A61K35/28 , A61K38/14 , A61K38/18 , A61K38/22 , A61K39/395 , A61K47/02 , A61M39/02
CPC分类号： A61K9/0024 , A61F2/022 , A61K31/337 , A61K31/397 , A61K31/436 , A61K31/65 , A61K31/7036 , A61K35/28 , A61K38/14 , A61K38/1866 , A61K38/22 , A61K39/395 , A61K47/02 , A61M39/0247 , A61M2039/0261 , A61M2039/027 , A61M2039/0276 , A61M2205/04
摘要： A material includes a metallic, nanoporous structure having a plurality of nanopores having a porosity that allows passage of insulin but not IgG. The metallic nanoporous structure includes titanium, 316L stainless steel and may have a textured nano-sericeous surface. A nanoporous bicontinuous structure can be integrated with nanopores.
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公开(公告)号：US20190008762A1
公开(公告)日：2019-01-10
申请号：US16128781
申请日：2018-09-12
IPC分类号： A61K9/00 , A61K38/18 , A61K31/337 , A61K31/397 , A61K31/436 , A61M39/02 , A61K47/02 , A61K39/395 , A61K38/22 , A61F2/02 , A61K38/14 , A61K35/28 , A61K31/7036 , A61K31/65
CPC分类号： A61K9/0024 , A61F2/022 , A61K31/337 , A61K31/397 , A61K31/436 , A61K31/65 , A61K31/7036 , A61K35/28 , A61K38/14 , A61K38/1866 , A61K38/22 , A61K39/395 , A61K47/02 , A61M39/0247 , A61M2039/0261 , A61M2039/027 , A61M2039/0276 , A61M2205/04
摘要： The invention relates to a metallic, nanoporous canister used to encapsulate cellular and/or biotherapeutic agents. The device is biocompatible and functions to wholly isolate a therapeutically active agent and/or cells therein. Their implantation, and survival in vivo, permits the local or systemic diffusion of their encapsulated cellular and/or biomolecular and therapeutics factors with the potential to promote repair of damaged or degenerated tissues in mammalian hosts, primarily humans.
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