-
1.发明公开公开(公告)号：US20230265150A1
公开(公告)日：2023-08-24
申请号：US18122768
申请日：2023-03-17
发明人： Shiow-Her CHIOU , Kuan-Chih CHOW , Jui-Hung SHIEN , Yi-Hsin FAN , Pei-Hua LIN , Pei-Shan WU
IPC分类号： C07K14/55 , C07K14/525 , C07K14/52 , C07K14/54 , C07K14/705 , A61K39/39
CPC分类号： C07K14/55 , C07K14/525 , C07K14/52 , C07K14/521 , C07K14/522 , C07K14/5421 , C07K14/70575 , A61K39/39 , C07K2319/00 , A61K2039/55533
摘要： The present invention provides a fusion protein, comprising a chemokine polypeptide, which is a chemokine or a receptor binding domain thereof; and a cytokine polypeptide connected to said chemokine polypeptide, which is an interleukin, a TNF-superfamily cytokine or a receptor-binding domain thereof; wherein the chemokine polypeptide and the cytokine polypeptide have a common target cell, and the fusion protein has an improved chemokine activity as compared to the chemokine polypeptide, and an improved cytokine activity as compared to the cytokine polypeptide.
-
公开(公告)号：US20170327554A1
公开(公告)日：2017-11-16
申请号：US15658929
申请日：2017-07-25
发明人： Shiow-Her CHIOU , Kuan-Chih CHOW , Jui-Hung SHIEN , Yi-Hsin FAN , Pei-Hua LIN , Pei-Shan WU
IPC分类号： C07K14/55 , C07K14/52 , C07K14/705 , C07K14/525 , A61K39/39 , C07K14/54 , A61K39/00
CPC分类号： A61K39/39 , A61K2039/55533 , C07K14/52 , C07K14/521 , C07K14/522 , C07K14/525 , C07K14/5421 , C07K14/55 , C07K14/70575 , C07K2319/00
摘要： The present invention provides a fusion protein, comprising a chemokine polypeptide, which is a chemokine or a receptor binding domain thereof; and a cytokine polypeptide connected to said chemokine polypeptide, which is an interleukin, a TNF-superfamily cytokine or a receptor-binding domain thereof; wherein the chemokine polypeptide and the cytokine polypeptide have a common target cell, and the fusion protein has an improved chemokine activity as compared to the chemokine polypeptide, and an improved cytokine activity as compared to the cytokine polypeptide.
-
搜索结果
2 条记录 (耗时 0.011 秒)
