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公开(公告)号：US11173231B2
公开(公告)日：2021-11-16
申请号：US16127872
申请日：2018-09-11
摘要： Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.
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公开(公告)号：US10071187B2
公开(公告)日：2018-09-11
申请号：US14835005
申请日：2015-08-25
CPC分类号： A61L27/50 , A61L27/24 , A61L27/3604 , A61L27/3633 , A61L27/3808 , A61L27/3826 , A61L2430/02 , A61L2430/06 , A61L2430/26 , A61L2430/28 , A61L2430/30 , A61L2430/32 , A61L2430/34 , C12M21/08 , C12M23/06 , C12M23/34 , C12M25/14 , C12N5/0062 , C12N2533/54
摘要： Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.
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公开(公告)号：US20140188250A1
公开(公告)日：2014-07-03
申请号：US14088606
申请日：2013-11-25
发明人： Neal E. Fearnot , Michael C. Hiles , Jeremy Metz , F. Joseph Obermiller , Andrew J. Kaucher , Steven Charlebois
IPC分类号： A61F2/01
CPC分类号： A61L27/60 , A61F2/0063 , A61F2/02 , A61F2002/0072 , A61F2210/0076 , A61F2250/0003 , A61F2250/0068 , A61L27/3633 , A61L27/38
摘要： Described are medical graft materials and devices which can be usefully modified with liquid additives such as cell suspensions, bioactive agents, or combinations of these. Also described are methods for making and using these medical graft materials and devices.
摘要翻译： 描述了可以用液体添加剂如细胞悬浮液，生物活性剂或它们的组合有效地改性的医用移植材料和装置。 还描述了制造和使用这些医用移植材料和装置的方法。
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公开(公告)号：US20220280696A1
公开(公告)日：2022-09-08
申请号：US17527679
申请日：2021-11-16
摘要： Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.
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公开(公告)号：US09931439B2
公开(公告)日：2018-04-03
申请号：US14088606
申请日：2013-11-25
发明人： Neal E. Fearnot , Michael C. Hiles , Jeremy Metz , F. Joseph Obermiller , Andrew J. Kaucher , Steven Charlebois
CPC分类号： A61L27/60 , A61F2/0063 , A61F2/02 , A61F2002/0072 , A61F2210/0076 , A61F2250/0003 , A61F2250/0068 , A61L27/3633 , A61L27/38
摘要： Described are medical graft materials and devices which can be usefully modified with liquid additives such as cell suspensions, bioactive agents, or combinations of these. The medical graft materials and devices can have a first outer surface and a second outer surface and can define an internal chamber between the first outer surface and the second outer surface. The medical graft materials and devices can also have at least one region of the graft material interrupting the chamber and surrounded by the chamber. Also described are methods for making and using these medical graft materials and devices.
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公开(公告)号：US20160082157A1
公开(公告)日：2016-03-24
申请号：US14835005
申请日：2015-08-25
CPC分类号： A61L27/50 , A61L27/24 , A61L27/3604 , A61L27/3633 , A61L27/3808 , A61L27/3826 , A61L2430/02 , A61L2430/06 , A61L2430/26 , A61L2430/28 , A61L2430/30 , A61L2430/32 , A61L2430/34 , C12M21/08 , C12M23/06 , C12M23/34 , C12M25/14 , C12N5/0062 , C12N2533/54
摘要： Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.
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公开(公告)号：US12121631B2
公开(公告)日：2024-10-22
申请号：US17527679
申请日：2021-11-16
CPC分类号： A61L27/50 , A61L27/24 , A61L27/3604 , A61L27/3633 , A61L27/3808 , A61L27/3826 , C12M21/08 , C12M23/06 , C12M23/34 , C12M25/14 , C12N5/0062 , A61L2430/02 , A61L2430/06 , A61L2430/26 , A61L2430/28 , A61L2430/30 , A61L2430/32 , A61L2430/34 , C12N2533/54
摘要： Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.
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公开(公告)号：US20190117843A1
公开(公告)日：2019-04-25
申请号：US16127872
申请日：2018-09-11
摘要： Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.
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9.发明申请公开(公告)号：US20150359940A1
公开(公告)日：2015-12-17
申请号：US14834971
申请日：2015-08-25
CPC分类号： A61L27/50 , A61L27/24 , A61L27/3604 , A61L27/3633 , A61L27/3808 , A61L27/3826 , A61L2430/02 , A61L2430/06 , A61L2430/26 , A61L2430/28 , A61L2430/30 , A61L2430/32 , A61L2430/34 , C12M21/08 , C12M23/06 , C12M23/34 , C12M25/14 , C12N5/0062 , C12N2533/54
摘要： Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.
摘要翻译： 描述了可用于制备用于给予患者的含细胞的移植材料的方法，细胞生长底物和装置。 可以在细胞生长底物中定义管状通道以促进细胞分布到底物中。 还描述了用于制备细胞接种组合物的方法和装置，在施用细胞之前预处理细胞生长底物的方法和装置，以及具有新基底的细胞接种移植物及其用途。
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公开(公告)号：US11077231B2
公开(公告)日：2021-08-03
申请号：US14834971
申请日：2015-08-25
摘要： Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.
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