-
公开(公告)号：US20230242923A1
公开(公告)日：2023-08-03
申请号：US18063629
申请日：2022-12-08
CPC分类号： C12N15/62 , C12N15/8243 , C12N15/8251 , C12P13/02 , C12P13/04 , C12N15/8257 , C12P13/14 , Y10T436/174614
摘要： Engineered polypeptides useful in synthesizing acyl amino acids are provided. Also provided are methods of making acyl amino acids using engineered polypeptides. In certain embodiments, an acyl amino acid produced using compositions and/or methods at the present invention comprises cocoyl glutamate.
-
公开(公告)号：US10093935B2
公开(公告)日：2018-10-09
申请号：US15282548
申请日：2016-09-30
摘要： Engineered polypeptides useful in synthesizing acyl amino acids are provided. Also provided are methods of making acyl amino acids using engineered polypeptides. In certain embodiments, an acyl amino acid produced using compositions and/or methods of the present invention comprises cocoyl glutamate.
-
公开(公告)号：US09970036B2
公开(公告)日：2018-05-15
申请号：US14776805
申请日：2014-03-14
IPC分类号： C12N1/20 , C12P13/02 , C12N9/00 , A01N37/36 , C07C235/06
CPC分类号： C12P13/02 , A01N37/36 , C07C235/06 , C12N9/93 , C12Y603/02
摘要： Engineered polypeptides useful in synthesizing acyl amino acids are provided. Also provided are methods of making acyl amino acids using engineered polypeptides.
-
公开(公告)号：US11155843B2
公开(公告)日：2021-10-26
申请号：US16823173
申请日：2020-03-18
IPC分类号： C12N9/80 , C12P13/02 , C12N9/00 , A01N37/36 , C07C235/06
摘要： In certain embodiments, the present invention comprises compositions and methods useful in the generation of acyl amino acids. In certain embodiments, the present invention provides an engineered polypeptide comprising a peptide synthetase domain; in some such embodiments, the engineered polypeptide comprises only a single peptide synthetase domain. In some embodiments, the present invention provides an engineered peptide synthetase that is substantially free of a thioesterase domain, and/or a reductase domain. In certain embodiments, the present invention provides an acyl amino acid composition comprising a plurality of different forms of an acyl amino acid. In some such compositions, substantially all of the acyl amino acids within the composition contain the same amino acid moiety and differ with respect to acyl moiety. We also described populations where the fatty acid si for example 95% one length (C14, myristic).
-
公开(公告)号：US20190062759A1
公开(公告)日：2019-02-28
申请号：US16119910
申请日：2018-08-31
摘要： Engineered polypeptides useful in synthesizing acyl amino acids are provided. Also provided are methods of making acyl amino acids using engineered polypeptides. In certain embodiments, an acyl amino acid produced using compositions and/or methods of the present invention comprises cocoyl glutamate.
-
公开(公告)号：US12031167B2
公开(公告)日：2024-07-09
申请号：US17481290
申请日：2021-09-21
IPC分类号： C12N9/80 , A01N37/36 , C07C235/06 , C12N9/00 , C12P13/02
CPC分类号： C12P13/02 , A01N37/36 , C07C235/06 , C12N9/80 , C12N9/93 , C12Y603/02
摘要： In certain embodiments, the present invention comprises compositions and methods useful in the generation of acyl amino acids. In certain embodiments, the present invention provides an engineered polypeptide comprising a peptide synthetase domain; in some such embodiments, the engineered polypeptide comprises only a single peptide synthetase domain. In some embodiments, the present invention provides an engineered peptide synthetase that is substantially free of a thioesterase domain, and/or a reductase domain. In certain embodiments, the present invention provides an acyl amino acid composition comprising a plurality of different forms of an acyl amino acid. In some such compositions, substantially all of the acyl amino acids within the composition contain the same amino acid moiety and differ with respect to acyl moiety. We also described populations where the fatty acid is for example 95% one length (C14, myristic).
-
公开(公告)号：US20220259626A1
公开(公告)日：2022-08-18
申请号：US17481290
申请日：2021-09-21
IPC分类号： C12P13/02 , C12N9/00 , C12N9/80 , A01N37/36 , C07C235/06
摘要： In certain embodiments, the present invention comprises compositions and methods useful in the generation of acyl amino acids. In certain embodiments, the present invention provides an engineered polypeptide comprising a peptide synthetase domain; in some such embodiments, the engineered polypeptide comprises only a single peptide synthetase domain. In some embodiments, the present invention provides an engineered peptide synthetase that is substantially free of a thioesterase domain, and/or a reductase domain. In certain embodiments, the present invention provides an acyl amino acid composition comprising a plurality of different forms of an acyl amino acid. In some such compositions, substantially all of the acyl amino acids within the composition contain the same amino acid moiety and differ with respect to acyl moiety. We also described populations where the fatty acid is for example 95% one length (C14, myristic).
-
公开(公告)号：US20210062234A1
公开(公告)日：2021-03-04
申请号：US16823173
申请日：2020-03-18
IPC分类号： C12P13/02 , C12N9/00 , C12N9/80 , A01N37/36 , C07C235/06
摘要： In certain embodiments, the present invention comprises compositions and methods useful in the generation of acyl amino acids. In certain embodiments, the present invention provides an engineered polypeptide comprising a peptide synthetase domain; in some such embodiments, the engineered polypeptide comprises only a single peptide synthetase domain. In some embodiments, the present invention provides an engineered peptide synthetase that is substantially free of a thioesterase domain, and/or a reductase domain. In certain embodiments, the present invention provides an acyl amino acid composition comprising a plurality of different forms of an acyl amino acid. In some such compositions, substantially all of the acyl amino acids within the composition contain the same amino acid moiety and differ with respect to acyl moiety. We also described populations where the fatty acid si for example 95% one length (C14, myristic).
-
公开(公告)号：US20180340198A1
公开(公告)日：2018-11-29
申请号：US15978634
申请日：2018-05-14
IPC分类号： C12P13/02 , C07C235/06 , C12N9/00 , A01N37/36
摘要： In certain embodiments, the present invention comprises compositions and methods useful in the generation of acyl amino acids. In certain embodiments, the present invention provides an engineered polypeptide comprising a peptide synthetase domain; in some such embodiments, the engineered polypeptide comprises only a single peptide synthetase domain. In some embodiments, the present invention provides an engineered peptide synthetase that is substantially free of a thioesterase domain, and/or a reductase domain. In certain embodiments, the present invention provides an acyl amino acid composition comprising a plurality of different forms of an acyl amino acid. In some such compositions, substantially all of the acyl amino acids within the composition contain the same amino acid moiety and differ with respect to acyl moiety. We also described populations where the fatty acid si for example 95% one length (C14, myristic).
-
公开(公告)号：US20160076065A1
公开(公告)日：2016-03-17
申请号：US14776805
申请日：2014-03-14
IPC分类号： C12P13/02 , A01N37/36 , C12N9/00 , C07C235/06
CPC分类号： C12P13/02 , A01N37/36 , C07C235/06 , C12N9/93 , C12Y603/02
摘要： Engineered polypeptides useful in synthesizing acyl amino acids are provided. Also provided are methods of making acyl amino acids using engineered polypeptides.
摘要翻译： 提供了可用于合成酰基氨基酸的工程化多肽。 还提供了使用工程改造的多肽制备酰基氨基酸的方法。
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.018 秒)
