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公开(公告)号：US20200270364A1
公开(公告)日：2020-08-27
申请号：US16864570
申请日：2020-05-01
Applicant: Merck Sharp & Dohme Corp. , Adimab, LLC
Inventor： Zhu Chen , Kenneth Ellsworth , James Milligan , Elizabeth Oldham , Dietmar Seiffert , Vaishnavi Ganti , Mohammad Tabrizifard , Bianka Prinz
IPC: C07K16/36 , A61K39/395
Abstract: Antibodies that bind the apple 3 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa as well as activation of FIX by FXIa are described.
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公开(公告)号：US20200317811A1
公开(公告)日：2020-10-08
申请号：US16864559
申请日：2020-05-01
Applicant: Merck Sharp & Dohme Corp. , Adimab, LLC
Inventor： Zhu Chen , Kenneth Ellsworth , James Milligan , Elizabeth Oldham , Dietmar Seiffert , Vaishnavi Ganti , Mohammad Tabrizifard , Bianka Prinz
IPC: C07K16/36 , A61K39/395
Abstract: Antibodies that bind the apple 3 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa as well as activation of FIX by FXIa are described.
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公开(公告)号：US20200308302A1
公开(公告)日：2020-10-01
申请号：US16864577
申请日：2020-05-01
Applicant: Merck Sharp & Dohme Corp. , Adimab, LLC
Inventor： Zhu Chen , Kenneth Ellsworth , James Milligan , Elizabeth Oldham , Dietmar Seiffert , Vaishnavi Ganti , Mohammad Tabrizifard , Bianka Prinz
IPC: C07K16/36 , A61K39/395
Abstract: Antibodies that bind the apple 3 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa as well as activation of FIX by FXIa are described.
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Patent Agency Ranking
公开(公告)号：US20170355780A1
公开(公告)日：2017-12-14
申请号：US15619620
申请日：2017-06-12
Applicant: Merck Sharp & Dohme Corp.
Inventor： Zhu Chen , Kenneth Ellsworth , James Milligan , Elizabeth Oldham , Dietmar Seiffert , Vaishnavi Ganti , Mohammad Tabrizifard
IPC: C07K16/36 , A61K39/395 , A61K39/00
Abstract: Antibodies that bind the apple 3 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa as well as activation of FIX by FXIa are described.
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公开(公告)号：US20170226225A1
公开(公告)日：2017-08-10
申请号：US15409607
申请日：2017-01-19
Applicant: Merck Sharp & Dohme Corp.
Inventor： Zhu Chen , Kenneth P. Ellsworth , James A. Milligan , Elizabeth Oldham , Dietmar Seiffert , Vaishnavi Ganti , Mohammad Tabrizifard
CPC classification number: C07K16/36 , A61K39/3955 , A61K2039/505 , A61K2039/545 , A61P7/02 , C07K14/745 , C07K16/30 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/71 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: Antibodies that bind the apple 2 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa are described.
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公开(公告)号：US20200255542A1
公开(公告)日：2020-08-13
申请号：US16864583
申请日：2020-05-01
Applicant: Merck Sharp & Dohme Corp. , Adimab, LLC
Inventor： Zhu Chen , Kenneth Ellsworth , James Milligan , Elizabeth Oldham , Dietmar Seiffert , Vaishnavi Ganti , Mohammad Tabrizifard , Bianka Prinz
IPC: C07K16/36 , A61K39/395
Abstract: Antibodies that bind the apple 3 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa as well as activation of FIX by FXIa are described.
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公开(公告)号：US10584179B2
公开(公告)日：2020-03-10
申请号：US16101861
申请日：2018-08-13
Applicant: Merck Sharp & Dohme Corp. , Adimab, LLC
Inventor： Zhu Chen , Kenneth P. Ellsworth , James A. Milligan , Elizabeth Oldham , Dietmar Seiffert , Vaishnavi Ganti , Mohammad Tabrizifard , Bianka Prinz
IPC: C07K16/36 , A61K39/395 , A61P7/02 , C07K16/30 , C07K14/745 , A61K39/00
Abstract: Antibodies that bind the apple 2 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa are described.
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公开(公告)号：US10053515B2
公开(公告)日：2018-08-21
申请号：US15409607
申请日：2017-01-19
Applicant: Merck Sharp & Dohme Corp. , Adimab, LLC
Inventor： Zhu Chen , Kenneth P. Ellsworth , James A. Milligan , Elizabeth Oldham , Dietmar Seiffert , Vaishnavi Ganti , Mohammad Tabrizifard , Bianka Prinz
IPC: C07K16/36 , A61K39/395 , A61P7/02 , C07K16/30 , C07K14/745 , A61K39/00
CPC classification number: C07K16/36 , A61K39/3955 , A61K2039/505 , A61K2039/545 , A61P7/02 , C07K14/745 , C07K16/30 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/71 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: Antibodies that bind the apple 2 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa are described.
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