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公开(公告)号：US20170158701A1
公开(公告)日：2017-06-08
申请号：US15325100
申请日：2015-07-16
Applicant: Merck Sharp & Dohme Corp.
Inventor： John Y. L. Chung , Feng Peng , Yonggang Chen , Amude Mahmoud Kassim , Cheng-yi Chen , Mathew Maust , Mark McLaughlin , Michael J. Zacuto , Qinghao Chen , Lushi Tan , Zhiguo Jake Song , Yang Cao , Feng Xu
IPC: C07D487/04 , A61K31/4162
CPC classification number: C07D487/04 , A61K31/4162 , C07D309/30
Abstract: A process for preparing a compound of structural Formula Ia: comprising Boc deprotection with TFA of, reductive amination of:
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公开(公告)号：US09862725B2
公开(公告)日：2018-01-09
申请号：US15325100
申请日：2015-07-16
Applicant: Merck Sharp & Dohme Corp.
Inventor： John Y. L. Chung , Feng Peng , Yonggang Chen , Amude Mahmoud Kassim , Cheng-yi Chen , Mathew Maust , Mark McLaughlin , Michael J. Zacuto , Qinghao Chen , Lushi Tan , Zhiguo Jake Song , Yang Cao , Feng Xu
IPC: C07D231/56 , C07D405/04 , C07C69/73 , C07F5/04 , C07D487/04 , A61K31/4162
CPC classification number: C07D487/04 , A61K31/4162 , C07D309/30
Abstract: A process for preparing a compound of structural Formula Ia: comprising Boc deprotection with TFA of, reductive amination of:
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公开(公告)号：US20180093992A1
公开(公告)日：2018-04-05
申请号：US15831895
申请日：2017-12-05
Applicant: Merck Sharp & Dohme Corp.
Inventor： John Y. L. Chung , Feng Peng , Yonggang Chen , Amude Mahmoud Kassim , Cheng-yi Chen , Mathew Maust , Mark McLaughlin , Michael J. Zacuto , Qinghao Chen , Lushi Tan , Zhiguo Jake Song , Yang Cao , Feng Xu
IPC: C07D487/04 , A61K31/4162
CPC classification number: C07D487/04 , A61K31/4162 , C07D309/30
Abstract: A process for preparing a compound of structural Formula Ia: comprising Boc deprotection with TFA of: and reductive amination of:
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公开(公告)号：US10053466B2
公开(公告)日：2018-08-21
申请号：US15831895
申请日：2017-12-05
Applicant: Merck Sharp & Dohme Corp.
Inventor： John Y. L. Chung , Feng Peng , Yonggang Chen , Amude Mahmoud Kassim , Cheng-yi Chen , Mathew Maust , Mark McLaughlin , Michael J. Zacuto , Qinghao Chen , Lushi Tan , Zhiguo Jake Song , Yang Cao , Feng Xu
IPC: C07D487/04 , A61K31/4162
Abstract: A process for preparing a compound of structural Formula Ia: comprising Boc deprotection with TFA of: and reductive amination of:
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