专利检索 ap:("Merck Sharp & Dohme Corp.") AND inv:"John Lampe" 第 1 页

1.

发明授权
Purine inhibitors of human phosphatidylinositol 3-kinase delta 有权

公开(公告)号：US11230547B2

公开(公告)日：2022-01-25

申请号：US16764448

申请日：2018-12-12

申请人： Merck Sharp & Dohme Corp.

发明人： Meredeth A. McGowan , Jason D. Katz , Matthew Christopher , Hua Zhou , David James Witter , Chaomin Li , John Lampe , Joey L. Methot , Abdelghani A. Achab , Xavier Fradera , Shimin Xu

IPC分类号： C07D487/08 , C07D519/00 , C07D403/14

摘要： The instant invention provides compounds of formulas Ia and Ib which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.