Patent search ap:("Medtronic Ardian Luxembourg S.a.r.l.") AND inv:"Joseph A. Traina" Page 1

1.

发明授权
Monitoring of neuromodulation using biomarkers 有权

公开(公告)号：US11338140B2

公开(公告)日：2022-05-24

申请号：US15667901

申请日：2017-08-03

Applicant: Medtronic Ardian Luxembourg S.a.r.l.

Inventor： Ayala Hezi-Yamit , Rudy Beasley , Susan Edwards , Lori Garcia , Michele Lee Silver , Christopher W. Storment , Carol M. Sullivan , Joseph A. Traina , Stefan Stoyanov Tunev

IPC: A61B5/145 , A61B18/14 , A61B5/00 , A61B18/02 , A61N1/36 , A61B18/00 , A61N1/05 , A61B5/20 , A61B5/15 , A61B5/157 , A61B10/00 , A61B18/18 , A61N1/32 , G01N33/68 , A61N1/40 , A61N7/02

Abstract: Provided herein are methods, devices, compositions, and kits for monitoring neuromodulation efficacy based on changes in the level or activity of one or more target biomarkers. One aspect includes a comparison of baseline and post-modulation levels of one or more biomarkers in bodily fluid that have each been collected from a human subject at a relevant time, and that may be used to assess the neuromodulation efficacy. The post-neuromodulation levels for the one or more biomarkers may be collected from the human subject within about 5 minutes to about 14 days post-neuromodulation.

2.

发明申请
MONITORING OF NEUROMODULATION USING BIOMARKERS 有权

公开(公告)号：US20220296891A1

公开(公告)日：2022-09-22

申请号：US17717958

申请日：2022-04-11

Applicant: Medtronic Ardian Luxembourg S.a.r.l.

Inventor： Ayala Hezi-Yamit , Rudy A. Beasley , Susan Thornton Edwards , Lori Garcia , Michele Lee Silver , Christopher W. Storment , Carol M. Sullivan , Joseph A. Traina , Stefan Stoyanov Tunev

IPC: A61N1/36 , A61N1/05 , A61B5/20 , A61B5/15 , A61B18/14 , A61B5/145 , A61B5/00

Abstract: Provided herein are methods, devices, compositions, and kits for monitoring neuromodulation efficacy based on changes in the level or activity of one or more target biomarkers.

3.

发明授权
Monitoring of neuromodulation using biomarkers 有权
Title translation: 使用生物标志物监测神经调节

公开(公告)号：US09510777B2

公开(公告)日：2016-12-06

申请号：US13791681

申请日：2013-03-08

Applicant: Medtronic Ardian Luxembourg S.a.r.l.

Inventor： Ayala Hezi-Yamit , Rudy Beasley , Susan Thornton Edwards , Lori Garcia , Michele Lee Silver , Christopher W. Storment , Carol M. Sullivan , Joseph A. Traina , Stefan Stoyanov Tunev

IPC: A61B18/18 , A61N1/32 , A61B5/15 , A61B5/157 , A61N1/36 , A61B5/145 , A61B5/00 , A61N1/05 , A61B10/00 , A61B5/20 , A61B18/14 , A61B18/00 , G01N33/68

CPC classification number: A61B5/157 , A61B5/1405 , A61B5/14503 , A61B5/14546 , A61B5/15003 , A61B5/150229 , A61B5/150992 , A61B5/20 , A61B5/201 , A61B5/4035 , A61B5/4836 , A61B5/4848 , A61B5/6851 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B10/0045 , A61B10/007 , A61B18/02 , A61B18/1492 , A61B18/18 , A61B2018/00166 , A61B2018/00214 , A61B2018/0022 , A61B2018/00279 , A61B2018/00345 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00875 , A61B2018/0212 , A61N1/05 , A61N1/32 , A61N1/36007 , A61N1/3605 , A61N1/40 , A61N7/02 , G01N33/68 , G01N2800/347

Abstract: Provided herein are methods, devices, compositions, and kits for monitoring neuromodulation efficacy based on detecting changes in the level or activity of one or more target biomarkers associated with neuromodulation, as well as methods and processes of performing neuromodulation that incorporate monitoring of neuromodulation efficacy based on changes in level or activity of one or more target biomarkers.

Abstract translation: 本文提供了用于监测神经调节功效的方法，装置，组合物和试剂盒，其基于检测与神经调节相关的一种或多种目标生物标志物的水平或活性的变化，以及进行神经调节的方法和过程，其纳入基于神经调节功效的监测关于一种或多种目标生物标志物的水平或活性的变化。