公开(公告)号：US20040057978A1

公开(公告)日：2004-03-25

申请号：US10246857

申请日：2002-09-19

Applicant: Medtronic, Inc.

Inventor： Michael F. Mattes ,  Alvin Rhorer

IPC: A61L002/00 ,  B05D003/00

CPC classification number: A61L27/34 ,  A61L27/30 ,  A61L29/043 ,  A61L29/10 ,  A61L31/082 ,  A61L31/10 ,  C08L5/04

Abstract: A process for fabricating a medical assembly having a medical device at least a portion of which is formed of inorganic material is provided. The medical assembly is suitable for substantially long-term implantation in a host animal. The process includes modifying a surface of the medical device to form a hydrophilic adhesion-promoting surface. The hydrophilic adhesion-promoting surface is coated with an alginate solution comprising alginate and the alginate is reacted with alkaline earth metal cations.

Abstract translation: 提供一种制造具有至少一部分由无机材料形成的医疗装置的医疗组件的方法。 医疗组件适合于在宿主动物中基本上长期植入。 该方法包括改变医疗装置的表面以形成亲水的增粘表面。 亲水性粘附促进表面用包含藻酸盐的藻酸盐溶液涂覆，藻酸盐与碱土金属阳离子反应。

公开(公告)号：US20040079277A1

公开(公告)日：2004-04-29

申请号：US10278471

申请日：2002-10-23

Applicant: Medtronic, Inc.

Inventor： Michael F. Mattes ,  Ralph B. Danzl

IPC: C30B023/00 ,  C30B025/00 ,  C30B028/12 ,  C30B028/14

CPC classification number: B81C1/00182 ,  B81B2203/0315 ,  B81C2201/0191

Abstract: A method for forming a suspended microstructure is provided. The method includes providing a monocrystalline target substrate and subjecting the surface of the monocrystalline target substrate to ion implantation to form a microstructure layer at the surface of the monocrystalline target substrate. An epitaxial material layer is formed overlying the microstructure layer. A handle substrate is provided and a patterned interposed material layer is provided between the epitaxial material layer and the handle substrate. The epitaxial material layer, the patterned interposed material layer and the handle substrate are affixed. The method further includes thermally treating the monocrystalline target substrate to effect separation between the microstructure layer and a remainder of the monocrystalline target substrate.