公开(公告)号：US20210315693A1

公开(公告)日：2021-10-14

申请号：US17359228

申请日：2021-06-25

申请人： Medtronic, Inc.

发明人： Charles Tabor ,  Carol E. Eberhardt ,  Timothy G. Laske ,  Timothy R. Ryan ,  Joseph C. Morrow ,  Tammy Y. Tam ,  Brian A. Glynn ,  Anne L. Brody Rubin ,  Michael J. Tuchek

IPC分类号： A61F2/24 ,  A61F2/01 ,  A61F2/07

摘要： A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stewed valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.

公开(公告)号：US20200030089A1

公开(公告)日：2020-01-30

申请号：US16503430

申请日：2019-07-03

申请人： Medtronic, Inc.

发明人： Charles Tabor ,  Carol E. Eberhardt ,  Timothy G. Laske ,  Timothy R. Ryan ,  Joseph C. Morrow ,  Tammy Y. Tam ,  Brian A. Glynn ,  Anne L. Brody Rubin ,  Michael J. Tuchek

IPC分类号： A61F2/24 ,  A61F2/01 ,  A61F2/07

摘要： A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stewed valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.

公开(公告)号：US20160296328A1

公开(公告)日：2016-10-13

申请号：US15099125

申请日：2016-04-14

申请人： Medtronic, Inc.

发明人： Charles Tabor ,  Carol E. Eberhardt ,  Timothy G. Laske ,  Timothy R. Ryan ,  Joseph C. Morrow ,  Tammy Y. Tam ,  Brian A. Glynn ,  Ann L. Brody Rubin ,  Michael J. Tuchek

IPC分类号： A61F2/24 ,  A61F2/01

CPC分类号： A61F2/2418 ,  A61F2/013 ,  A61F2/07 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2/89 ,  A61F2/90 ,  A61F2002/016 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/0006 ,  A61F2230/0054 ,  A61F2230/008 ,  A61F2250/0018 ,  A61F2250/003 ,  A61F2250/0039

摘要： A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stented valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.

摘要翻译： 一种支架式阀，包括大致管状的支架结构，其具有纵向轴线，第一和第二相对端部，与第一和第二端部间隔开并且大致平行于纵向轴线延伸的多个连合支撑结构，至少一个结构线定位在 每个两个相邻的连合支撑结构，以及从两个相邻的合金支撑结构延伸并且朝向支架结构的第一和第二端中的一个延伸的至少一个翼部。 支架瓣膜还包括附接在大致管状支架结构内的连接支撑结构的瓣膜结构。

公开(公告)号：US09339382B2

公开(公告)日：2016-05-17

申请号：US14163842

申请日：2014-01-24

申请人： Medtronic, Inc.

发明人： Charles Tabor ,  Carol E. Eberhardt ,  Timothy G. Laske ,  Timothy R. Ryan ,  Joseph C. Morrow ,  Tammy Y. Tam ,  Brian A. Glynn ,  Anne L. Brody Rubin ,  J. Michael Tuchek

IPC分类号： A61F2/24 ,  A61F2/01 ,  A61F2/07 ,  A61F2/89 ,  A61F2/90

CPC分类号： A61F2/2418 ,  A61F2/013 ,  A61F2/07 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2/89 ,  A61F2/90 ,  A61F2002/016 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/0006 ,  A61F2230/0054 ,  A61F2230/008 ,  A61F2250/0018 ,  A61F2250/003 ,  A61F2250/0039

摘要： A stented valve prosthesis for implantation within a native mitral valve having a generally tubular expandable stent structure having a first end, a second end, a central body portion having one or more openings, and a longitudinal axis. A wing portion extends outwardly from the stent structure and away from the longitudinal axis of the stent structure in an expanded deployed configuration. A radius of the wing portion is greater than a radius of the central body portion in the expanded deployed configuration, and the wing portion fits within one of the openings in the central body portion of the stent structure in a crimped delivery configuration. A valve structure having a plurality of leaflets is attached to an interior of the stent structure.

摘要翻译： 一种用于植入天然二尖瓣内的支架瓣膜假体，其具有大致管状的可扩张支架结构，其具有第一端，第二端，具有一个或多个开口的中心体部分和纵向轴线。 翼部分从支架结构向外延伸并且以展开的部署构型远离支架结构的纵向轴线延伸。 翼部分的半径大于扩展展开构造中的中心体部分的半径，并且翼部分以卷曲输送构型装配在支架结构的中心主体部分中的一个开口内。 具有多个叶片的瓣膜结构附接到支架结构的内部。

公开(公告)号：US08511244B2

公开(公告)日：2013-08-20

申请号：US13656247

申请日：2012-10-19

申请人： Medtronic, Inc.

发明人： Arin N. Holecek ,  Carolyn Majkrzak ,  Janice L. Shay ,  Carol E. Eberhardt ,  David L. Kulcinski

IPC分类号： D05B39/00 ,  A61F2/24

CPC分类号： A61F2/2415 ,  A61F2220/0075 ,  Y10T29/53552

摘要： A method of assembling a prosthetic valve using sheets of material, such as pericardium material, polymer or bioengineered film, or other material. The method provides an accurate and repeatable system of making pericardial valves in which sheets or pieces of material are held securely in place relative to each other throughout the steps of assembling the valve. In addition, methods of the present invention include maintaining consistent alignment of the fixtures and pericardium material throughout the valve assembly process and utilize features that make the tooling components easy to assemble and handle. Certain aspects of the invention can be used to help establish a repeatable sewing and cutting technique for creating a pattern shape for valve leaflets, establishing stitch lengths, and determining the exact placement of stitches.

摘要翻译： 使用诸如心包材料，聚合物或生物工程薄膜或其他材料的材料片组装人造瓣的方法。 该方法提供精确和可重复的制造心包瓣膜的系统，其中片材或片材在组装阀门的整个步骤中相对于彼此牢固地保持在适当的位置。 此外，本发明的方法包括在整个阀门组装过程中保持固定装置和心包膜材料的一致的对准，并利用使加工组件易于组装和处理的特征。 本发明的某些方面可以用于建立可重复的缝合和切割技术，以创建用于瓣叶的图案形状，建立针迹长度以及确定针迹的确切位置。

公开(公告)号：US11284999B2

公开(公告)日：2022-03-29

申请号：US17359228

申请日：2021-06-25

申请人： Medtronic, Inc.

发明人： Charles Tabor ,  Carol E. Eberhardt ,  Timothy G. Laske ,  Timothy R. Ryan ,  Joseph C. Morrow ,  Tammy Y. Tam ,  Brian A. Glynn ,  Anne L. Brody Rubin ,  Michael J. Tuchek

IPC分类号： A61F2/24 ,  A61F2/01 ,  A61F2/07 ,  A61F2/89 ,  A61F2/90 ,  A61F2/915

摘要： A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stewed valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.

公开(公告)号：US10646335B2

公开(公告)日：2020-05-12

申请号：US16031019

申请日：2018-07-10

申请人： Medtronic, Inc.

发明人： Charles Tabor ,  Carol E. Eberhardt ,  Timothy G. Laske ,  Timothy R. Ryan ,  Joseph C. Morrow ,  Tammy Y. Tam ,  Brian A. Glynn ,  Anne L. Brody Rubin ,  Michael J. Tuchek

IPC分类号： A61F2/24 ,  A61F2/01 ,  A61F2/07 ,  A61F2/89 ,  A61F2/90 ,  A61F2/915

摘要： A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stewed valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.

公开(公告)号：US10548723B2

公开(公告)日：2020-02-04

申请号：US15793639

申请日：2017-10-25

申请人： Medtronic, Inc.

发明人： Alexander J. Hill ,  Cynthia Clague ,  Carol E. Eberhardt ,  Ana Menk ,  Mark J. Capps ,  Billie Millwee ,  Janice Lynn Shay ,  Debra Taitague ,  Joseph C. Morrow ,  Jerald Redmond

IPC分类号： A61F2/24

摘要： A stented valve having at least one leaflet made of pericardium or other material having a relatively thin profile at the annulus. The leaflets are attached via chords to a stent frame, where the chords are positioned to mimic the native valve anatomy and functionality. In particular, the valves of one exemplary embodiment of the invention are sized to replace a mitral valve and therefore the chords are arranged to prevent prolapse of the leaflets into the atrium. The stented valve has a relatively short height at its annulus due to the positioning of the chords. In addition, the stented valve is capable of being crimped to a small enough size that it can be delivered to the implantation site via transcatheter delivery systems and methods.

公开(公告)号：US10335280B2

公开(公告)日：2019-07-02

申请号：US15098494

申请日：2016-04-14

申请人： Medtronic, Inc.

发明人： James R. Keogh ,  Timothy R. Ryan ,  Carol E. Eberhardt ,  Mark T. Stewart ,  James R. Skarda ,  Timothy G. Laske ,  Alexander J. Hill ,  Jack D. Lemmon ,  David E. Francischelli

IPC分类号： A61N7/02 ,  A61F2/24 ,  A61B5/00 ,  A61B5/107 ,  A61B8/00 ,  A61B34/20 ,  A61B90/00 ,  A61B18/14 ,  A61B17/00 ,  A61B18/00

摘要： A method for treating a human patient includes emitting ultrasound energy from an ultrasound transducer positioned remotely from target tissue of the patient. The ultrasound transducer is positioned at a desired location relative to the patient and target tissue using location and imaging techniques. The method further includes focusing the ultrasound energy such that one or more focal points are directed to the target tissue of the patient and ablating the target tissue at each focal point. The target tissue is ablated via the focused ultrasound energy without ablating non-target tissue through which the ultrasound energy passes between the ultrasound transducer and the one or more focal points.

公开(公告)号：US09333100B2

公开(公告)日：2016-05-10

申请号：US14087990

申请日：2013-11-22

申请人： Medtronic, Inc.

发明人： Carol E. Eberhardt ,  Charles Tabor ,  Carolyn Majkrzak ,  Timothy R. Ryan ,  Melissa Young ,  Maria Awad ,  Janice L. Shay

IPC分类号： A61F2/24 ,  A61F2/82 ,  A61F2/95

CPC分类号： A61F2/2418 ,  A61F2/2403 ,  A61F2/2412 ,  A61F2/243 ,  A61F2/2436 ,  A61F2/82 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2250/0098

摘要： A stented valve including a stent structure including a generally tubular body portion having a first end, a second end, an interior area, a longitudinal axis, and a plurality of vertical wires extending generally parallel to the longitudinal axis around a periphery of the body portion, wherein the plurality of vertical wires includes multiple commissure wires and at least one structural wire positioned between adjacent commissure wires, and a plurality of V-shaped wire structures having a first end, a second end, and a peak between the first and second ends, wherein a first end of each V-shaped structure extends from a first vertical wire and a second end of each V-shaped structure extends from a second vertical wire that is adjacent to the first vertical wire, wherein each V-shaped structure is oriented so that its peak is facing in the same direction relative to the first and second ends of the body portion, and a valve structure including a plurality of leaflets attached to the stent structure within the tubular body portion.

摘要翻译： 一种支架式阀，包括支架结构，该支架结构包括大体上管状的主体部分，该主体部分具有第一端部，第二端部，内部区域，纵向轴线以及大致平行于纵向轴线围绕主体部分的周边延伸的多个垂直线 ，其中所述多个垂直导线包括多个连合线和位于相邻合金线之间的至少一个结构线，以及多个V形线结构，其具有第一端，第二端和在所述第一和第二端之间的峰 其中，每个V形结构的第一端从第一垂直线延伸，并且每个V形结构的第二端从与所述第一垂直线相邻的第二垂直线延伸，其中每个V形结构被定向 使得其峰值相对于主体部分的第一和第二端面向相同的方向，以及阀结构，其包括附接到ste的多个传单 nt结构在管状体部分内。