公开(公告)号：US12115149B2

公开(公告)日：2024-10-15

申请号：US17523323

申请日：2021-11-10

申请人： MedRegen, LLC

发明人： Zhaoli Sun ,  John Sun ,  Christy Eatmon ,  Rachel Labell ,  Zhimin Liu ,  Richard Brewer ,  Isaac Agyemang ,  Mitchell Williams

IPC分类号： A61K31/436 ,  A61K9/00 ,  A61K31/495 ,  A61K47/02 ,  A61K47/10 ,  A61K47/22 ,  A61P11/00 ,  A61P29/00

CPC分类号： A61K31/436 ,  A61K9/0019 ,  A61K31/495 ,  A61K47/02 ,  A61K47/10 ,  A61K47/22 ,  A61P11/00 ,  A61P29/00

摘要： Embodiments of the disclosure relate generally to formulations, methods, kits, and dosage forms for improved stability comprising at least two active ingredients, AMD3100, or similar stem cell mobilizer, and Tacrolimus, or FK506 derivative or analog, and one or more excipients. The formulations may be administered as a single dose subcutaneous injection. The formulations may be useful in treating various diseases, disorders or injuries.

公开(公告)号：US20220142992A1

公开(公告)日：2022-05-12

申请号：US17523323

申请日：2021-11-10

申请人： MedRegen, LLC

发明人： Zhaoli Sun ,  John Sun ,  Jared Griffin ,  Christy Eatmon ,  Rachel Labell ,  Zhimin Liu ,  Richard Brewer ,  Issac Agyemang ,  Mitchell Williams

IPC分类号： A61K31/436 ,  A61K31/495 ,  A61K47/10 ,  A61K47/22 ,  A61K47/02 ,  A61K9/00 ,  A61P11/00 ,  A61P29/00

摘要： Embodiments of the disclosure relate generally to formulations, methods, kits, and dosage forms for improved stability comprising at least two active ingredients, AMD3100, or similar stem cell mobilizer, and Tacrolimus, or FK506 derivative or analog, and one or more excipients. The formulations may be administered as a single dose subcutaneous injection. The formulations may be useful in treating various diseases, disorders or injuries.