公开(公告)号：US20180318345A1

公开(公告)日：2018-11-08

申请号：US16029423

申请日：2018-07-06

申请人： LiveLeaf, Inc.

发明人： Alexander Huang ,  Gin Wu

IPC分类号： A61K33/40 ,  A61K31/352 ,  A61K31/353 ,  A61K31/7048 ,  A61K36/185 ,  A61K31/7034 ,  A61K36/22 ,  A61K45/06 ,  A61K31/7028 ,  A61K31/192 ,  A61K36/82

CPC分类号： A61K33/40 ,  A61K31/192 ,  A61K31/352 ,  A61K31/353 ,  A61K31/7028 ,  A61K31/7034 ,  A61K31/7048 ,  A61K36/185 ,  A61K36/22 ,  A61K36/82 ,  A61K45/06 ,  A61K2300/00

摘要： Methods of inhibiting the virulence of a pathogen to treat a gastrointestinal spasm in a subject, without killing the pathogen, are provided. The methods can include administering an effective amount of a formulation to treat the gastrointestinal spasm, the formulation having a tannin combined with a hydroxyl radical in a pharmaceutically acceptable excipient as a binding pair, the tannin releasing in an oxidized state from the hydrogen donor after oral administration of the formulation in the subject; wherein, the composition at least inhibits a gastrointestinal spasm in the subject when compared to a second subject in a control group in which the composition was not administered.