公开(公告)号：US20160299097A1

公开(公告)日：2016-10-13

申请号：US15184133

申请日：2016-06-16

申请人： LifeScan Scotland Limited

发明人： Timothy LLOYD ,  David MCCOLL ,  Antony SMITH ,  Brian GUTHRIE ,  David ELDER ,  Rossano MASSARI ,  Christian FORLANI

IPC分类号： G01N27/327

CPC分类号： G01N27/3273 ,  G01N27/3274 ,  G01N27/3275

摘要： An analyte meter having a test strip port is configured to transmit an electric signal through a received test strip with a sample. A pair of electrodes apply the electric signal and receive an electrical response from the test strip. A processing unit analyzes the electrical response and uses the response to determine an analyte level of the sample.

摘要翻译： 具有测试条端口的分析物计量器被配置为通过带有样品的接收的测试条来传输电信号。 一对电极施加电信号并从测试条接收电响应。 处理单元分析电响应并使用响应来确定样品的分析物水平。

公开(公告)号：US20150355131A1

公开(公告)日：2015-12-10

申请号：US14300454

申请日：2014-06-10

申请人： LifeScan Scotland Limited

发明人： David ELDER ,  Rossano MASSARI

IPC分类号： G01N27/327

CPC分类号： G01N27/3273 ,  G01N27/3271 ,  G01N27/3274 ,  G01R23/20 ,  G01R29/26

摘要： A hand-held test meter for use with an analytical test strip in the determination of an analyte in a bodily fluid sample includes a housing, a clock module disposed in the housing, a micro-controller disposed in the housing, a low-distortion signal generation circuit block (“LDSGCB”) disposed in the housing, and a strip port connector configured to operationally receive the analytical test strip. The LDSGCB includes a signal summation circuit (“SSC”) sub-block, a resistance-capacitance (RC) filter, and a single operational amplifier. The clock module and micro-controller are configured to generate phase-shifted square wave signals and output the phase-shifted square wave signals to the SSC. The SSC is configured to sum the phase-shifted square wave signals to generate a resultant summed-wave signal and output the resultant summed-wave signal to the RC filter. The RC filter is configured to filter harmonics from the resultant summed-wave signal thereby creating a reduced harmonic distortion signal.

摘要翻译： 用于测定体液样品中的分析物的分析测试条的手持式测试仪包括壳体，设置在壳体中的时钟模块，设置在壳体中的微控制器，低失真信号 设置在壳体中的发生电路块（“LDSGCB”）以及被配置为可操作地接收分析测试条的条形端口连接器。 LDSGCB包括信号求和电路（“SSC”）子块，电阻电容（RC）滤波器和单个运算放大器。 时钟模块和微控制器被配置为产生相移方波信号并将相移的方波信号输出到SSC。 SSC被配置为对相移的方波信号求和以产生合成的和波信号，并将所得的和波信号输出到RC滤波器。 RC滤波器被配置为从所得到的和波信号中滤除谐波，从而产生减小的谐波失真信号。

公开(公告)号：US20150177176A1

公开(公告)日：2015-06-25

申请号：US14138820

申请日：2013-12-23

申请人： Lifescan Scotland Limited

发明人： Rossano MASSARI ,  Emanuele Pozzi ,  Tim Lloyd ,  David Elder

IPC分类号： G01N27/30

CPC分类号： G01N27/307 ,  G01N33/48785

摘要： An analyte meter having a test strip port is configured to detect an inserted test strip using an unpowered grounded op amp while the analyte meter is in sleep mode. After a test strip is inserted and the meter is activated, the op amp is powered and provides the sample current for measuring an analyte concentration in the sample.

摘要翻译： 具有测试条端口的分析物计量器被配置为在分析物仪处于睡眠模式时使用未供电的接地运算放大器检测插入的测试条。 在插入测试条并且仪表被激活之后，运算放大器被供电并提供用于测量样品中分析物浓度的样品电流。

公开(公告)号：US20160178560A1

公开(公告)日：2016-06-23

申请号：US14574512

申请日：2014-12-18

申请人： LifeScan Scotland Limited

发明人： David ELDER ,  Rossano MASSARI ,  Christian FORLANI ,  Emanuele POZZI

IPC分类号： G01N27/327

CPC分类号： G01N27/3273 ,  G01N27/3274

摘要： An analyte measurement system and method for determining a test strip current through an analyte of a physiological fluid sample on a test strip. The system includes a variable reference direct current voltage source and a fixed reference direct current voltage source forming a voltage bias across the electrodes of the test strip. The system also can include an integrator circuit comprising a capacitor and an operational amplifier. In one embodiment, a bias current circuit including a bias current resistor network, and provides a bias current. In another embodiment, the system can include an integrator circuit transistor switch configured to reset the integrator circuit.

摘要翻译： 分析物测量系统和方法，用于确定通过测试条上的生理流体样品的分析物的测试条电流。 该系统包括可变参考直流电压源和固定的参考直流电压源，其形成跨越测试条的电极的电压偏置。 该系统还可以包括包括电容器和运算放大器的积分器电路。 在一个实施例中，偏置电流电路包括偏置电流电阻网络，并提供偏置电流。 在另一个实施例中，系统可以包括被配置为复位积分器电路的积分器电路晶体管开关。

公开(公告)号：US20150192563A1

公开(公告)日：2015-07-09

申请号：US14660001

申请日：2015-03-17

申请人： LifeScan Scotland Limited

发明人： David ELDER ,  Timothy LLOYD ,  Christian FORLANI ,  Rossano MASSARI ,  Emanuele POZZI

IPC分类号： G01N33/49

CPC分类号： G01N33/49 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/1486 ,  A61B5/7225 ,  A61B2560/0209 ,  A61B2562/0295 ,  G01N27/3273 ,  G01N27/3274

摘要： A hand-held test meter includes a strip port connector to receive a test strip. A signal-measurement circuit applies a periodic voltage signal across a sample applied to the strip and detects a resulting current signal. The circuit provides data of the current signal at a digitizing frequency and a selected phase with respect to the voltage signal. A processor records one or more value(s) of the data and then alters the selected phase. Value(s) are thus recorded at each of a plurality of phases. The processor determines a phase difference of the current signal with respect to the voltage signal using the respective sets of value(s). A method for employing a test meter and a test strip is also disclosed, and includes measuring a respective plurality of points for each of a plurality of different measurement phases and determining a phase difference of a fluid sample therefrom.

公开(公告)号：US20160320328A1

公开(公告)日：2016-11-03

申请号：US15104995

申请日：2014-12-22

申请人： LIFESCAN SCOTLAND LIMITED

发明人： Timothy LLOYD ,  David MCCOLL ,  Rossano MASSARI ,  Christian FORLANI

IPC分类号： G01N27/327

CPC分类号： G01N27/3274 ,  G01N27/3273

摘要： A hand-held test meter for use with an electrochemical-based analytical test strip in the determination of an analyte in a bodily fluid sample includes a housing (110), a micro-controller (112) disposed in the housing, an operating range test strip simulation circuit block (“ORTSSCB” 114) disposed in the housing and a strip port connector (“SPC” 106) configured to operationally receive an electrochemical-based analytical test strip. The ORTSSCB is in electrical communication with the SPC. In addition, the ORTSSCB is configured to simulate an electrochemical-based analytical test strip inserted into the SPC and an operating range of bodily fluid samples applied to such an electrochemical-based analytical test strip by sequentially presenting a plurality of electrical loads. Each of the plurality of electrical loads is configured as a first resistor in series with a parallel configuration of a second resistor and a first capacitor. Moreover, the SPC is configured in electrical communication with the micro-controller.

摘要翻译： 用于测定体液样品中的分析物的基于电化学的分析测试条的手持测试仪包括壳体（110），设置在壳体中的微控制器（112），操作范围测试 设置在壳体中的带状模拟电路块（“ORTSSCB”114）“和配置成可操作地接收基于电化学的分析测试条的条形端口连接器（”SPC“106”）。 ORTSSCB与SPC电气通信。 此外，ORTSSCB被配置为模拟插入到SPC中的基于电化学的分析测试条和通过依次呈现多个电负载而施加到这种基于电化学的分析测试条的体液样品的操作范围。 多个电负载中的每一个被配置为与第二电阻器和第一电容器的并联配置串联的第一电阻器。 此外，SPC被配置为与微控制器电通信。

公开(公告)号：US20150369769A1

公开(公告)日：2015-12-24

申请号：US14313377

申请日：2014-06-24

申请人： LifeScan Scotland Limited

发明人： Alexander COOPER ,  Antony SMITH ,  Lynsey WHYTE ,  Neil WHITEHEAD ,  David MCCOLL ,  Brian GUTHRIE ,  Timothy LLOYD ,  Rossano MASSARI ,  Christian FORLANI

IPC分类号： G01N27/327

CPC分类号： G01N27/327 ,  B01L2300/0645 ,  G01N27/3272 ,  G01N31/164 ,  G01N33/0031 ,  G01N2030/645

摘要： An electrochemical-based analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample (for example, a whole blood sample) and/or a characteristic of the bodily fluid sample (e.g., hematocrit) includes a sample-entry chamber with a sample-application opening disposed on an end edge of the electrochemical-based analytical test strip, and first and second sample-determination chambers, each in direct fluidic communication with the sample-entry chamber. The electrochemical-based analytical test strip also includes first and second electrodes (such as first and second hematocrit electrodes) disposed in the first sample-determination chamber, and a third and fourth electrodes (for example working and reference electrodes) disposed in the second sample-determination chamber. Moreover, the first and second sample-determination chambers intersect the sample-entry chamber perpendicular (or nearly perpendicular) to one another and the first sample-determination chamber also intersects the sample-entry chamber in an aligned manner.

摘要翻译： 用于测定体液样品（例如全血样品）中的分析物（例如葡萄糖）和/或体液样品的特征（例如，血细胞比容）的基于电化学的分析测试条包括样品 具有设置在基于电化学的分析测试条的端部边缘上的样品施加开口的第一和第二样品室，以及与样品入口室直接流体连通的第一和第二样品测定室。 基于电化学的分析测试条还包括设置在第一样品测定室中的第一和第二电极（例如第一和第二血细胞比容电极）和设置在第二样品中的第三和第四电极（例如工作和参考电极） 测定室。 此外，第一和第二样品确定室将样品入口室彼此垂直（或几乎垂直）相交，并且第一样品测定室也以对准的方式与样品入口室相交。