公开(公告)号：US10197529B2

公开(公告)日：2019-02-05

申请号：US15130532

申请日：2016-04-15

申请人： LIFE TECHNOLOGIES CORPORATION

发明人： David A. Denny ,  David Woo ,  Manjula Aliminati ,  Siva Kumar Samsani ,  Stephanie J. Schneider ,  Yoke Peng Lim ,  Sylvia Chang

IPC分类号： G01N27/447 ,  G06F19/22

摘要： In one exemplary embodiment, a method for detecting variants in electropherogram data is provided. The method includes receiving electropherogram data from an instrument and analyzing the electropherogram data to identify mixed bases in the electropherogram data. The method further includes identifying features within the electropherogram data indicative of errors and validating the identified mixed bases. Then the method includes determining variants in the electropherogram data based on the validated mixed bases.

公开(公告)号：US10557821B2

公开(公告)日：2020-02-11

申请号：US16265806

申请日：2019-02-01

申请人： Life Technologies Corporation

发明人： David Denny ,  David Woo ,  Manjula Aliminati ,  Siva Kumar Samsani ,  Stephanie Schneider ,  Yoke Peng Lim ,  Sylvia Chang

IPC分类号： G01N27/447 ,  G16B30/00

摘要： In one exemplary embodiment, a method for detecting variants in electropherogram data is provided. The method includes receiving electropherogram data from an instrument and analyzing the electropherogram data to identify mixed bases in the electropherogram data. The method further includes validating the identified mixed bases. Then the method includes determining variants in the electropherogram data based on the validated mixed bases.

公开(公告)号：US20160313280A1

公开(公告)日：2016-10-27

申请号：US15130532

申请日：2016-04-15

申请人： LIFE TECHNOLOGIES CORPORATION

发明人： David A. Denny ,  David Woo ,  Manjula Aliminati ,  Siva Kumar Samsani ,  Stephanie J. Schneider ,  Yoke Peng Lim ,  Sylvia Chang

IPC分类号： G01N27/447

CPC分类号： G01N27/44717 ,  G06F19/22

摘要： In one exemplary embodiment, a method for detecting variants in electropherogram data is provided. The method includes receiving electropherogram data from an instrument and analyzing the electropherogram data to identify mixed bases in the electropherogram data. The method further includes identifying features within the electropherogram data indicative of errors and validating the identified mixed bases. Then the method includes determining variants in the electropherogram data based on the validated mixed bases.

摘要翻译： 在一个示例性实施例中，提供了一种用于检测电泳图数据中的变体的方法。 该方法包括从仪器接收电泳图数据，并分析电泳图数据以识别电泳图数据中的混合碱基。 该方法还包括识别电泳图中指示错误并验证所识别的混合碱基的特征。 然后该方法包括基于经验证的混合碱基来确定电泳图数据中的变体。