公开(公告)号：US11464622B2

公开(公告)日：2022-10-11

申请号：US16694968

申请日：2019-11-25

申请人： LensGen, Inc.

发明人： Daniel Brady ,  Thomas Silvestrini ,  Ramgopal Rao

IPC分类号： A61F2/16 ,  A61B90/00 ,  A61F2/14

摘要： A two-part accommodating intraocular lens (IOL) device for implantation in a capsular bag of a patient's eye. The IOL device includes a primary lens assembly and a power changing lens. The primary lens assembly includes a fixed lens and a peripherally disposed centration member. The centration member has a circumferential distal edge and a first coupling surface adjacent the circumferential distal edge. The power changing lens has an enclosed, fluid- or gel-filled lens cavity and haptic system disposed peripherally of the lens cavity. The haptic system has a peripheral engaging edge configured to contact the capsular bag and a second coupling surface. The first and second coupling surfaces are in sliding contact with one another to permit movement of the power changing lens relative to the primary lens assembly and also to maintain a spaced relationship between the fixed lens and the lens cavity during radial compression of the power changing lens.

公开(公告)号：US11464621B2

公开(公告)日：2022-10-11

申请号：US16678318

申请日：2019-11-08

申请人： LensGen, Inc.

发明人： Daniel Brady ,  Thomas Silvestrini ,  Ramgopal Rao

IPC分类号： A61F2/16

摘要： An accommodating intraocular lens (IOL) can be implanted either alone or as part of a two-part lens assembly. The IOL comprises an optic, a flexible membrane and a peripheral edge coupling the optic and the flexible membrane. The peripheral edge comprises an external circumferential surface having a height and a force transmitting area defined along a portion of the height of the external circumferential surface. A closed volume spaces apart the optic and the flexible membrane. The optic is axially displaced and the flexible membrane changes in curvature about a central axis when a radial compressive force is applied to the force transmitting area. A volume defined by the closed volume remains fixed when the optic is axially displaced and the flexible membrane changes in curvature and/or when the radial compressive force is applied to the force transmitting area.

公开(公告)号：US20210205134A1

公开(公告)日：2021-07-08

申请号：US17147820

申请日：2021-01-13

申请人： LensGen, Inc.

发明人： Ramgopal Rao ,  Thomas Silvestrini

IPC分类号： A61F9/008 ,  A61F2/16

摘要： A method for adjusting the refractive power of a fluid-filled intraocular lens implanted into a patients eye. The method comprises selecting a pattern to cause a flattening of the intraocular lens or an increase in curvature of the intraocular lens, and ablating the pattern, onto either an optical element of the intraocular lens or a flexible element of the intraocular lens, to alter either one or both of a refractive power and an amplitude of accommodation of the intraocular lens. The ablating occurs while the intraocular lens remains implanted in the patient's eye. The ablating maintains the integrity of a fluid-filled interior cavity defined between the optical element and the flexible element, but causes the flattening of the intraocular lens or the increase in curvature of the intraocular lens.

公开(公告)号：US20220338975A1

公开(公告)日：2022-10-27

申请号：US17720592

申请日：2022-04-14

申请人： LensGen, Inc.

发明人： Daniel Brady ,  Thomas Silvestrini ,  Ramgopal Rao

IPC分类号： A61F2/16

摘要： An accommodating intraocular lens (IOL) can be implanted either alone or as part of a two-part lens assembly. The IOL comprises an optic, a flexible membrane and a peripheral edge coupling the optic and the flexible membrane. The peripheral edge comprises an external circumferential surface having a height and a force transmitting area defined along a portion of the height of the external circumferential surface. A closed volume spaces apart the optic and the flexible membrane. The optic is axially displaced and the flexible membrane changes in curvature about a central axis when a radial compressive force is applied to the force transmitting area. A volume defined by the closed volume remains fixed when the optic is axially displaced and the flexible membrane changes in curvature and/or when the radial compressive force is applied to the force transmitting area.

公开(公告)号：US11471273B2

公开(公告)日：2022-10-18

申请号：US17514717

申请日：2021-10-29

申请人： LensGen, Inc.

发明人： Daniel Brady ,  Thomas Silvestrini ,  Ramgopal Rao

IPC分类号： A61F2/16 ,  A61B90/00 ,  A61F2/14

摘要： A two-part accommodating intraocular lens (IOL) device for implantation in a capsular bag of a patient's eye. The IOL device includes a primary lens assembly and a power changing lens. The primary lens assembly includes a fixed lens and a peripherally disposed centration member. The centration member has a circumferential distal edge and a first coupling surface adjacent the circumferential distal edge. The power changing lens has an enclosed, fluid- or gel-filled lens cavity and haptic system disposed peripherally of the lens cavity. The haptic system has a peripheral engaging edge configured to contact the capsular bag and a second coupling surface. The first and second coupling surfaces are in sliding contact with one another to permit movement of the power changing lens relative to the primary lens assembly and also to maintain a spaced relationship between the fixed lens and the lens cavity during radial compression of the power changing lens.

公开(公告)号：US11331183B2

公开(公告)日：2022-05-17

申请号：US16678318

申请日：2019-11-08

申请人： LensGen, Inc.

发明人： Daniel Brady ,  Thomas Silvestrini ,  Ramgopal Rao

IPC分类号： A61F2/16

摘要： An accommodating intraocular lens (IOL) can be implanted either alone or as part of a two-part lens assembly. The IOL comprises an optic, a flexible membrane and a peripheral edge coupling the optic and the flexible membrane. The peripheral edge comprises an external circumferential surface having a height and a force transmitting area defined along a portion of the height of the external circumferential surface. A closed volume spaces apart the optic and the flexible membrane. The optic is axially displaced and the flexible membrane changes in curvature about a central axis when a radial compressive force is applied to the force transmitting area. A volume defined by the closed volume remains fixed when the optic is axially displaced and the flexible membrane changes in curvature and/or when the radial compressive force is applied to the force transmitting area.

公开(公告)号：US20200085568A1

公开(公告)日：2020-03-19

申请号：US16694968

申请日：2019-11-25

申请人： LensGen, Inc.

发明人： Daniel Brady ,  Thomas Silvestrini ,  Ramgopal Rao

IPC分类号： A61F2/16 ,  A61B90/00

摘要： A two-part accommodating intraocular lens (IOL) device for implantation in a capsular bag of a patient's eye. The IOL device includes a primary lens assembly and a power changing lens. The primary lens assembly includes a fixed lens and a peripherally disposed centration member. The centration member has a circumferential distal edge and a first coupling surface adjacent the circumferential distal edge. The power changing lens has an enclosed, fluid- or gel-filled lens cavity and haptic system disposed peripherally of the lens cavity. The haptic system has a peripheral engaging edge configured to contact the capsular bag and a second coupling surface. The first and second coupling surfaces are in sliding contact with one another to permit movement of the power changing lens relative to the primary lens assembly and also to maintain a spaced relationship between the fixed lens and the lens cavity during radial compression of the power changing lens.

公开(公告)号：US20180271645A1

公开(公告)日：2018-09-27

申请号：US15996188

申请日：2018-06-01

申请人： LensGen, Inc.

发明人： Daniel Brady ,  Thomas Silvestrini ,  Ramgopal Rao

IPC分类号： A61F2/16 ,  A61F9/007

CPC分类号： A61F2/16 ,  A61F2/1624 ,  A61F2/1648 ,  A61F9/00736 ,  A61F2002/1681 ,  A61F2002/1682 ,  A61F2002/169 ,  A61F2220/0033 ,  B29D11/02 ,  B29D11/026 ,  G02B3/14 ,  G02C7/04 ,  G02C7/08

摘要： An accommodating intraocular lens device is provided. The accommodating intraocular lens device comprises a base assembly and a power lens. The base assembly comprises a first open end, a second end coupled to a base lens, and a haptic surrounding a central cavity. The haptic may comprise an outer periphery, an inner surface and a height between a first edge and a second edge. The power lens is configured to fit within the central cavity. The power lens may comprise a first side, a second side, a peripheral edge coupling the first and second sides, and a closed cavity configured to house a fluid. The first side of the power lens may be positioned at a predetermined distance from the first edge of the haptic.

公开(公告)号：US20160030161A1

公开(公告)日：2016-02-04

申请号：US14447621

申请日：2014-07-31

申请人： LensGen, Inc.

发明人： Daniel Brady ,  Thomas Silvestrini ,  Ramgopal Rao

IPC分类号： A61F2/16

CPC分类号： A61F2/1635 ,  A61F2/1629 ,  A61F2/1648 ,  A61F2002/1697 ,  A61F2250/0018

摘要： An accommodating intraocular lens (IOL) can be implanted either alone or as part of a two-part lens assembly. The IOL comprises an optic, a flexible membrane and a peripheral edge coupling the optic and the flexible membrane. The peripheral edge comprises an external circumferential surface having a height and a force transmitting area defined along a portion of the height of the external circumferential surface. A closed volume spaces apart the optic and the flexible membrane. The optic is axially displaced and the flexible membrane changes in curvature about a central axis when a radial compressive force is applied to the force transmitting area. A volume defined by the closed volume remains fixed when the optic is axially displaced and the flexible membrane changes in curvature and/or when the radial compressive force is applied to the force transmitting area.

摘要翻译： 可以单独或作为两部分透镜组件的一部分植入适应性眼内透镜（IOL）。 IOL包括光学元件，柔性膜和连接光学元件和柔性膜的外围边缘。 周缘包括外周表面，该外周表面具有沿着外周表面的高度的一部分限定的高度和力传递区域。 闭合的体积与光学元件和柔性膜分开。 当径向压缩力施加到力传递区域时，光学元件被轴向移位，并且柔性膜围绕中心轴线变化曲率。 当光学元件轴向移位并且柔性膜在曲率上变化时和/或当径向压力施加到力传递区域时，由闭合容积限定的体积保持固定。

公开(公告)号：US09186244B2

公开(公告)日：2015-11-17

申请号：US13725895

申请日：2012-12-21

申请人： LensGen, Inc.

发明人： Thomas Silvestrini ,  Ramgopal Rao

IPC分类号： A61F2/16

CPC分类号： A61F2/1613 ,  A61F2/16 ,  A61F2/1616 ,  A61F2/1629 ,  A61F2/1635 ,  A61F2/1648 ,  A61F2002/169 ,  A61F2250/0003 ,  A61F2250/0004 ,  A61F2250/0008

摘要： An accommodating intraocular lens (IOL) comprises a lens, a flexible surface, and an articulating member joining the lens and the flexible surface. The articulating member comprises first and second arms extending from and joined to form a peripheral portion. The peripheral portion has a length extending radially away from a point at which the first and second arms join together and a thickness that is greater than each of a thickness of the first arm and a thickness of the second arm, first and second arms coupling the lens and the flexible surface, respectively. A flex region is disposed about the second arm and at a distance from the peripheral portion. The flex region permits the flexible surface to articulate relative to the second arm. The flex region has a reduced thickness as compared to each of the second arm and the flexible surface.

摘要翻译： 容纳眼内透镜（IOL）包括透镜，柔性表面和接合透镜和柔性表面的铰接构件。 所述铰接构件包括第一和第二臂，所述第一和第二臂从所述第一和第二臂延伸并连接以形成周 周边部分具有从第一和第二臂接合在一起的点径向延伸的长度，其厚度大于第一臂的厚度和第二臂的厚度，第一和第二臂将 镜片和柔性表面。 弯曲区域围绕第二臂设置并且与周边部分一定距离。 柔性区域允许柔性表面相对于第二臂铰接。 柔性区域与第二臂和柔性表面中的每一个相比具有减小的厚度。