公开(公告)号：US09918971B2

公开(公告)日：2018-03-20

申请号：US15156796

申请日：2016-05-17

Applicant: LUXENA PHARMACEUTICALS, INC.

Inventor： George Lu ,  Xiaodong Li ,  Biao Lu

IPC: A61K9/14 ,  A61K31/439 ,  A61K31/46 ,  A61K9/00 ,  A61K9/16 ,  A61K47/26

CPC classification number: A61K31/439 ,  A61K9/0075 ,  A61K9/008 ,  A61K9/1623 ,  A61K31/46 ,  A61K47/26

Abstract: Aerosol formulations of granisetron useful for pulmonary delivery are provided. The formulations are useful in the reduction, elimination or prevention of nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. Also provided are novel methods to treat chemotherapy-induced nausea and vomiting (CINV), radiation-induced nausea and vomiting (RINV), and post-operative nausea and vomiting (PONV) using the inhalation formulations.

公开(公告)号：US20150010633A1

公开(公告)日：2015-01-08

申请号：US14323115

申请日：2014-07-03

Applicant: Luxena Pharmaceuticals, Inc.

Inventor： Xiaodong LI ,  George Lu

IPC: A61K9/16 ,  A61K9/00 ,  A61K31/4178

CPC classification number: A61K9/0075 ,  A61K9/008 ,  A61K9/16 ,  A61K9/1623 ,  A61K31/4178 ,  A61K47/26

Abstract: Aerosol formulations of ondansetron useful for pulmonary delivery are provided. The formulations are useful in the reduction, elimination or prevention of nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. Also provided are novel methods to treat chemotherapy-induced nausea and vomiting (CINV), radiation-induced nausea and vomiting (RINV), and post-operative nausea and vomiting (PONV) using the inhalation formulations.

Abstract translation: 提供昂丹司琼可用于肺部输送的气溶胶制剂。 该制剂可用于减少，消除或预防与化疗，放射治疗和手术相关的恶心和呕吐。 还提供了使用吸入制剂治疗化学疗法诱发的恶心和呕吐（CINV），放射诱导的恶心和呕吐（RINV）以及术后恶心呕吐（PONV）的新方法。

公开(公告)号：US20150010632A1

公开(公告)日：2015-01-08

申请号：US14323089

申请日：2014-07-03

Applicant: Luxena Pharmaceuticals, Inc.

Inventor： George Lu ,  Xiaodong Li

IPC: A61K31/46 ,  A61K47/06 ,  A61K47/26 ,  A61K9/00

CPC classification number: A61K31/439 ,  A61K9/0075 ,  A61K9/008 ,  A61K9/1623 ,  A61K31/46 ,  A61K47/26

Abstract: Aerosol formulations of granisetron useful for pulmonary delivery are provided. The formulations are useful in the reduction, elimination or prevention of nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. Also provided are novel methods to treat chemotherapy-induced nausea and vomiting (CINV), radiation-induced nausea and vomiting (RINV), and post-operative nausea and vomiting (PONV) using the inhalation formulations.

Abstract translation: 提供了可用于肺部输送的格拉司琼的气溶胶制剂。 该制剂可用于减少，消除或预防与化疗，放射治疗和手术相关的恶心和呕吐。 还提供了使用吸入制剂治疗化学疗法诱发的恶心和呕吐（CINV），放射诱导的恶心和呕吐（RINV）以及术后恶心呕吐（PONV）的新方法。

公开(公告)号：US09770409B2

公开(公告)日：2017-09-26

申请号：US15154431

申请日：2016-05-13

Applicant: LUXENA PHARMACEUTICALS, INC.

Inventor： Xiaodong Li ,  George Lu ,  Biao Lu

IPC: A61K9/14 ,  A61K9/00 ,  A61K31/4178 ,  A61K9/16 ,  A61K47/26

CPC classification number: A61K9/0075 ,  A61K9/008 ,  A61K9/16 ,  A61K9/1623 ,  A61K31/4178 ,  A61K47/26

Abstract: Aerosol formulations of ondansetron useful for pulmonary delivery are provided. The formulations are useful in the reduction, elimination or prevention of nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. Also provided are novel methods to treat chemotherapy-induced nausea and vomiting (CINV), radiation-induced nausea and vomiting (RINV), and post-operative nausea and vomiting (PONV) using the inhalation formulations.