专利检索 ap:("LONZA BIOLOGICS PLC") AND inv:"Christopher M. Smales" 第 1 页

1.

发明授权
Means and methods for the generation of mammalian producer cells for the production of recombinant proteins 审中-公开

公开(公告)号：US10669541B2

公开(公告)日：2020-06-02

申请号：US14910267

申请日：2014-07-30

申请人： LONZA BIOLOGICS PLC

发明人： Marc Feary , James Rance , Robert Young , Elizabeth C. Sayer , Christopher M. Smales

IPC分类号： C12N15/113 , C12P21/00 , C12N15/11 , C07K16/00

摘要： Methods for generating mammalian cells characterized by an increased concentration of at least one of miR-15, miR-16, and miR-34 for producing proteins at an industrial scale are provided. Methods for using the mammalian cells, in particular for the production of proteins of interest, are also provided.