- 专利标题： Means and methods for the generation of mammalian producer cells for the production of recombinant proteins
-
申请号： US14910267申请日： 2014-07-30
-
公开(公告)号： US10669541B2公开(公告)日： 2020-06-02
- 发明人: Marc Feary , James Rance , Robert Young , Elizabeth C. Sayer , Christopher M. Smales
- 申请人： LONZA BIOLOGICS PLC
- 申请人地址： GB Slough
- 专利权人： LONZA BIOLOGICS PLC.
- 当前专利权人： LONZA BIOLOGICS PLC.
- 当前专利权人地址： GB Slough
- 代理机构： Lucas & Mercanti, LLP
- 优先权： com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@76bbbc6e
- 国际申请： PCT/EP2014/066352 WO 20140730
- 国际公布： WO2015/018703 WO 20150212
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; C12P21/00 ; C12N15/11 ; C07K16/00
摘要：
Methods for generating mammalian cells characterized by an increased concentration of at least one of miR-15, miR-16, and miR-34 for producing proteins at an industrial scale are provided. Methods for using the mammalian cells, in particular for the production of proteins of interest, are also provided.
公开/授权文献
信息查询
IPC分类:
