公开(公告)号：US20140053095A1

公开(公告)日：2014-02-20

申请号：US14063940

申请日：2013-10-25

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Gordon A. Janaway ,  Evelyn Wing-Sim Chan

IPC: G06F19/26

CPC classification number: G06F19/18 ,  G06F3/0482 ,  G06F3/0485 ,  G06F19/26

Abstract: Systems and methods are used to display data obtained from a qPCR instrument. Each of two or more samples is probed with a first labeling probe and a second labeling probe. A first data set is received from a qPCR instrument at a first cycle number that includes for each sample a first labeling probe intensity, and a second labeling probe intensity. A second data set is received at a second cycle number that includes for each sample a first labeling probe intensity and a second labeling probe intensity. A first plot of first labeling probe intensity as a function of second labeling probe intensity is created using the first data set. A second plot of first labeling probe intensity as a function of second labeling probe intensity is created using the second data set. The first plot and the second plot are displayed in response to user defined input to provide dynamic and real-time analysis of genotyping data.

Abstract translation: 系统和方法用于显示从qPCR仪器获得的数据。 用第一标记探针和第二标记探针探测两个或更多个样品中的每一个。 从qPCR仪器以第一周期数接收第一数据集，其中包括针对每个样本的第一标记探针强度和第二标记探针强度。 以第二周期数接收第二数据集，其中为每个样本包括第一标记探针强度和第二标记探针强度。 使用第一数据集创建第一标记探针强度作为第二标记探针强度的函数的第一图。 使用第二数据集创建第二标记探针强度作为第二标记探针强度的函数的第二图。 显示第一个绘图和第二个绘图以响应用户定义的输入，以提供对基因分型数据的动态和实时分析。

公开(公告)号：US20170011165A1

公开(公告)日：2017-01-12

申请号：US15206109

申请日：2016-07-08

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Gordon A. Janaway ,  Evelyn Wing-Sim Chan

IPC: G06F19/18 ,  G06F3/0482 ,  G06F19/26

CPC classification number: G06F19/18 ,  G06F3/0482 ,  G06F3/0485 ,  G06F19/26

Abstract: Systems and methods are used to display data obtained from a qPCR instrument. Each of two or more samples is probed with a first labeling probe and a second labeling probe. A first data set is received from a qPCR instrument at a first cycle number that includes for each sample a first labeling probe intensity, and a second labeling probe intensity. A second data set is received at a second cycle number that includes for each sample a first labeling probe intensity and a second labeling probe intensity. A first plot of first labeling probe intensity as a function of second labeling probe intensity is created using the first data set. A second plot of first labeling probe intensity as a function of second labeling probe intensity is created using the second data set. The first plot and the second plot are displayed in response to user defined input to provide dynamic and real-time analysis of genotyping data.

Abstract translation: 系统和方法用于显示从qPCR仪器获得的数据。 用第一标记探针和第二标记探针探测两个或更多个样品中的每一个。 从qPCR仪器以第一周期数接收第一数据集，其中包括针对每个样本的第一标记探针强度和第二标记探针强度。 以第二周期数接收第二数据集，其中为每个样本包括第一标记探针强度和第二标记探针强度。 使用第一数据集创建第一标记探针强度作为第二标记探针强度的函数的第一图。 使用第二数据集创建第二标记探针强度作为第二标记探针强度的函数的第二图。 显示第一个绘图和第二个绘图以响应用户定义的输入，以提供对基因分型数据的动态和实时分析。

公开(公告)号：US20190130995A1

公开(公告)日：2019-05-02

申请号：US16172330

申请日：2018-10-26

Applicant: Life Technologies Corporation

Inventor： Gordon A. Janaway ,  Evelyn Wing-Sim Chan

IPC: G16B20/00 ,  G16B45/00 ,  G06F3/0482 ,  G06F3/0485

Abstract: Systems and methods are used to display data obtained from a qPCR instrument. Each of two or more samples is probed with a first labeling probe and a second labeling probe. A first data set is received from a qPCR instrument at a first cycle number that includes for each sample a first labeling probe intensity, and a second labeling probe intensity. A second data set is received at a second cycle number that includes for each sample a first labeling probe intensity and a second labeling probe intensity. A first plot of first labeling probe intensity as a function of second labeling probe intensity is created using the first data set. A second plot of first labeling probe intensity as a function of second labeling probe intensity is created using the second data set. The first plot and the second plot are displayed in response to user defined input to provide dynamic and real-time analysis of genotyping data.

公开(公告)号：US09390227B2

公开(公告)日：2016-07-12

申请号：US14063940

申请日：2013-10-25

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Gordon A. Janaway ,  Evelyn Wing-Sim Chan

IPC: G06F3/00 ,  G06F19/26 ,  G06F19/18

CPC classification number: G06F19/18 ,  G06F3/0482 ,  G06F3/0485 ,  G06F19/26

Abstract: Systems and methods are used to display data obtained from a qPCR instrument. Each of two or more samples is probed with a first labeling probe and a second labeling probe. A first data set is received from a qPCR instrument at a first cycle number that includes for each sample a first labeling probe intensity, and a second labeling probe intensity. A second data set is received at a second cycle number that includes for each sample a first labeling probe intensity and a second labeling probe intensity. A first plot of first labeling probe intensity as a function of second labeling probe intensity is created using the first data set. A second plot of first labeling probe intensity as a function of second labeling probe intensity is created using the second data set. The first plot and the second plot are displayed in response to user defined input to provide dynamic and real-time analysis of genotyping data.

公开(公告)号：US10127348B2

公开(公告)日：2018-11-13

申请号：US15206109

申请日：2016-07-08

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Gordon A. Janaway ,  Evelyn Wing-Sim Chan

IPC: G06F3/048 ,  G06F19/18 ,  G06F19/26 ,  G06F3/0482 ,  G06F3/0485

Abstract: Systems and methods are used to display data obtained from a qPCR instrument. Each of two or more samples is probed with a first labeling probe and a second labeling probe. A first data set is received from a qPCR instrument at a first cycle number that includes for each sample a first labeling probe intensity, and a second labeling probe intensity. A second data set is received at a second cycle number that includes for each sample a first labeling probe intensity and a second labeling probe intensity. A first plot of first labeling probe intensity as a function of second labeling probe intensity is created using the first data set. A second plot of first labeling probe intensity as a function of second labeling probe intensity is created using the second data set. The first plot and the second plot are displayed in response to user defined input to provide dynamic and real-time analysis of genotyping data.