公开(公告)号：US10328024B2

公开(公告)日：2019-06-25

申请号：US15525835

申请日：2016-09-23

Applicant: LG Chem, Ltd. ,  LG Household & Health Care Ltd.

Inventor： Jeong Ae Yoon ,  Su Jeong Kim ,  Sun Hwa Lee ,  Woo Sun Shim ,  Sung Soo Yoon ,  Chang Hwan Ju ,  Jung A Kim ,  Nae Gyu Kang

IPC: A61K8/02 ,  A61K8/06 ,  A61K8/11 ,  A61K8/90 ,  A61K9/00 ,  A61K9/51 ,  A61K9/107 ,  A61Q19/00 ,  C08G81/00 ,  C08G81/02 ,  A61K31/352 ,  C08F293/00

Abstract: The present application relates to an amphiphilic polymer and a method of preparing the same. Furthermore, the present application relates to a micelle including a drug encapsulated by the amphiphilic polymer and a composition including the same. The amphiphilic polymer according to the present application has excellent drug encapsulation properties as well as good dispersion properties in an aqueous solution.

公开(公告)号：US10143651B2

公开(公告)日：2018-12-04

申请号：US15355225

申请日：2016-11-18

Applicant: LG Chem, Ltd. ,  LG Household & Health Care Ltd.

Inventor： Su Jeong Kim ,  Jeong Ae Yoon ,  Sun Hwa Lee ,  Woo Sun Shim ,  Sung Soo Yoon ,  Chang Hwan Ju ,  Jung A Kim ,  Nae Gyu Kang

IPC: A61K47/32 ,  A61K9/107 ,  A61K31/352

Abstract: The present application relates to a micelle comprising a drug encapsulated by an amphiphilic polymer and a composition comprising the same. The micelle of the present application has an excellent dispersion property on an aqueous solution and a superior percutaneous absorption characteristic on preparing a formulation.

公开(公告)号：US11160755B2

公开(公告)日：2021-11-02

申请号：US16303529

申请日：2017-06-16

Applicant: LG CHEM, LTD. ,  LG HOUSEHOLD & HEALTH CARE LTD.

Inventor： Su Jeong Kim ,  Jeong Ae Yoon ,  Sun Hwa Lee ,  Woo Sun Shim ,  Sung Soo Yoon ,  Chang Hwan Ju ,  Kyung Oh Kim ,  Jung A Kim ,  Nae Gyu Kang

IPC: A61K9/107 ,  A61K31/353 ,  A61K31/366 ,  A61K31/575 ,  C08F293/00 ,  C08F297/02

Abstract: The present application relates to an amphiphilic polymer and a method for producing the same. The present application also relates to micelles comprising the amphiphilic polymer and a method for producing the same. The amphiphilic polymer of the present application can have excellent dispersion properties while effectively encapsulating the drug.

公开(公告)号：US20190254970A1

公开(公告)日：2019-08-22

申请号：US16404889

申请日：2019-05-07

Applicant: LG Chem, Ltd. ,  LG Household & Health Care Ltd.

Inventor： Jeong Ae Yoon ,  Su Jeong Kim ,  Sun Hwa Lee ,  Woo Sun Shim ,  Sung Soo Yoon ,  Chang Hwan Ju ,  Jung A. Kim ,  Nae Gyu Kang

IPC: A61K9/107 ,  C08G81/02 ,  A61K31/352 ,  A61K9/51 ,  A61K9/00 ,  A61K8/11 ,  A61K8/06 ,  A61K8/02 ,  A61K8/90 ,  A61Q19/00 ,  C08F293/00 ,  C08G81/00

Abstract: The present application relates to an amphiphilic polymer and a method of preparing the same. Furthermore, the present application relates to a micelle including a drug encapsulated by the amphiphilic polymer and a composition including the same. The amphiphilic polymer according to the present application has excellent drug encapsulation properties as well as good dispersion properties in an aqueous solution.

公开(公告)号：US10251819B2

公开(公告)日：2019-04-09

申请号：US15525838

申请日：2016-09-23

Applicant: LG Chem, Ltd. ,  LG Household & Health Care Ltd.

Inventor： Jeong Ae Yoon ,  Su Jeong Kim ,  Sun Hwa Lee ,  Woo Sun Shim ,  Sung Soo Yoon ,  Chang Hwan Ju ,  Jung A Kim ,  Nae Gyu Kang

IPC: A61K8/02 ,  A61K8/06 ,  A61K8/72 ,  A61K9/51 ,  A61K9/107 ,  C08F26/10 ,  C08G12/06 ,  C08G65/34 ,  C08G81/00 ,  C08F293/00

Abstract: The present application relates to an amphiphilic polymer and a method of preparing the same. Furthermore, the present application relates to a micelle including a drug encapsulated by the amphiphilic polymer and a composition including the same. The amphiphilic polymer according to the present application has excellent drug encapsulation properties as well as good dispersion properties in an aqueous solution.

公开(公告)号：US10857099B2

公开(公告)日：2020-12-08

申请号：US16404889

申请日：2019-05-07

Applicant: LG Chem, Ltd. ,  LG Household & Health Care Ltd.

Inventor： Jeong Ae Yoon ,  Su Jeong Kim ,  Sun Hwa Lee ,  Woo Sun Shim ,  Sung Soo Yoon ,  Chang Hwan Ju ,  Jung A. Kim ,  Nae Gyu Kang

IPC: A61K9/107 ,  A61K8/02 ,  A61K8/06 ,  A61K9/51 ,  C08G81/00 ,  C08F293/00 ,  A61Q19/00 ,  A61K8/90 ,  A61K8/11 ,  A61K9/00 ,  A61K31/352 ,  C08G81/02

Abstract: The present application relates to an amphiphilic polymer and a method of preparing the same. Furthermore, the present application relates to a micelle including a drug encapsulated by the amphiphilic polymer and a composition including the same. The amphiphilic polymer according to the present application has excellent drug encapsulation properties as well as good dispersion properties in an aqueous solution.

公开(公告)号：US11034786B2

公开(公告)日：2021-06-15

申请号：US16304048

申请日：2017-06-16

Applicant: LG CHEM, LTD. ,  LG HOUSEHOLD & HEALTH CARE LTD.

Inventor： Kyung Oh Kim ,  Su Jeong Kim ,  Sun Hwa Lee ,  Woo Sun Shim ,  Jeong Ae Yoon ,  Sung Soo Yoon ,  Chang Hwan Ju ,  Jung A Kim ,  Nae Gyu Kang

IPC: C08F293/00 ,  A61K9/107 ,  A61K47/32 ,  C08F220/06 ,  C08F220/14

Abstract: The present application relates to an amphiphilic triblock polymer and micelles comprising the amphiphilic triblock polymer. The amphiphilic triblock polymer of the present application can have excellent dispersion properties and excellent water solubility while effectively encapsulating the drug.

公开(公告)号：US20170360703A1

公开(公告)日：2017-12-21

申请号：US15525835

申请日：2016-09-23

Applicant: LG Chem, Ltd. ,  LG Household & Health Care Ltd.

Inventor： Jeong Ae Yoon ,  Su Jeong Kim ,  Sun Hwa Lee ,  Woo Sun Shim ,  Sung Soo Yoon ,  Chang Hwan Ju ,  Jung A Kim ,  Nae Gyu Kang

IPC: A61K9/107 ,  A61K31/352 ,  A61K9/51 ,  C08G81/02 ,  A61K9/00

CPC classification number: A61K9/107 ,  A61K8/02 ,  A61K8/06 ,  A61K8/11 ,  A61K8/90 ,  A61K9/0014 ,  A61K9/51 ,  A61K9/5138 ,  A61K31/352 ,  A61K2800/10 ,  A61K2800/56 ,  A61Q19/00 ,  C08F293/00 ,  C08G81/00 ,  C08G81/025

Abstract: The present application relates to an amphiphilic polymer and a method of preparing the same.Furthermore, the present application relates to a micelle including a drug encapsulated by the amphiphilic polymer and a composition including the same.The amphiphilic polymer according to the present application has excellent drug encapsulation properties as well as good dispersion properties in an aqueous solution.

公开(公告)号：US20170354576A1

公开(公告)日：2017-12-14

申请号：US15525838

申请日：2016-09-23

Applicant: LG Chem, Ltd. ,  LG Household & Health Care Ltd.

Inventor： Jeong Ae Yoon ,  Su Jeong Kim ,  Sun Hwa Lee ,  Woo Sun Shim ,  Sung Soo Yoon ,  Chang Hwan Ju ,  Jung A Kim ,  Nae Gyu Kang

IPC: A61K8/02 ,  C08G81/00 ,  A61K9/51 ,  A61K8/06 ,  C08F293/00 ,  A61K8/72 ,  A61K9/107 ,  C08F26/10 ,  C08G65/34 ,  C08G12/06

CPC classification number: A61K8/02 ,  A61K8/06 ,  A61K8/72 ,  A61K9/107 ,  A61K9/51 ,  C08F26/10 ,  C08F293/00 ,  C08F293/005 ,  C08F2438/01 ,  C08G12/06 ,  C08G65/34 ,  C08G81/00

Abstract: The present application relates to an amphiphilic polymer and a method of preparing the same.Furthermore, the present application relates to a micelle including a drug encapsulated by the amphiphilic polymer and a composition including the same.The amphiphilic polymer according to the present application has excellent drug encapsulation properties as well as good dispersion properties in an aqueous solution.

公开(公告)号：US20170143628A1

公开(公告)日：2017-05-25

申请号：US15355225

申请日：2016-11-18

Applicant: LG Chem, Ltd. ,  LG Household & Health Care Ltd.

Inventor： Su Jeong Kim ,  Jeong Ae Yoon ,  Sun Hwa Lee ,  Woo Sun Shim ,  Sung Soo Yoon ,  Chang Hwan Ju ,  Jung A Kim ,  Nae Gyu Kang

IPC: A61K9/107 ,  A61K47/32 ,  A61K31/352

CPC classification number: A61K9/1075 ,  A61K9/0014 ,  A61K31/352 ,  A61K47/10 ,  A61K47/32

Abstract: The present application relates to a micelle comprising a drug encapsulated by an amphiphilic polymer and a composition comprising the same.The micelle of the present application has an excellent dispersion property on an aqueous solution and a superior percutaneous absorption characteristic on preparing a formulation.