摘要:
A time-of-flight mass spectrometer (TOF MS) comprises a mass analyzer, an ion pushing device, a filtering device, a multi-pass reflector, a detector, and a decoder. The ion pushing device is arranged to push ions into the mass analyzer. The filtering device is arranged to filter a portion of the ions based on a mass range of the ions. The multi-pass reflector is arranged to selectively reflect the ions for further passes through the mass analyzer. The detector is arranged to receive the ions. The decoder is arranged to reconstruct a mass spectrum for the entire mass range of the ions.
摘要:
A data acquisition system and method are described that may be used with various spectrometers. The data acquisition system may include an ion detector, an initial processing module, and a spectra processing module. The initial processing module is provided for processing the ion detection signals and for supplying processed signals to the spectra processing module. The spectra processing module generates spectra from the processed signals and supplies the generated spectra to an external processor for post-processing. The spectra processing module may include an ion statistics filter and/or a peak histogram filtering circuit.
摘要:
A method for processing chromatographic peaks in chromatographic systems comprising comparing a first peak with a second peak; and determining whether the first peak and second peak should be grouped together.
摘要:
Implementations of methods and apparatuses are disclosed for decoding multiplexed information in a chromatographic system. Implementations may include the method of pulsing ions from an ion source through an analyzer according to a predetermined multiplexing scheme, each pulse including one or more ions corresponding to a sample, detecting a plurality of ion strikes at a detector, determining a data point for each ion strike, wherein each data point includes an intensity of a detected ion strike and a time of the detected ion strike, maintaining a multiplexed spectrum of the data points, the multiplexed spectrum including the data points, and demultiplexing the time shifted spectrum using the data points of the multiplexed spectrum.
摘要:
A method of adjusting a baseline value in data received from a mass spectrometer includes generating a plurality of data signal values with a converter. The method also includes categorizing the plurality of data signal values relative to a plurality of threshold values. The plurality of threshold values include a high value, a mid-high value, a mid-low value, and a low value. The method further includes determining (i) a first quantity of data signal values categorized between the high value and the mid-high values, (ii) a second quantity of data signal values categorized between the mid-high value and the mid-low value, and (iii) a third quantity of data signal values categorized between the mid-low value and the low value. The method also includes generating a table of the first quantity of data signal values, the second quantity of data signal values, and the third quantity of data signal values. The method further includes determining whether to increase, decrease, or maintain the baseline value based on the first quantity, the second quantity, and the third quantity.
摘要:
Implementations of methods and apparatuses are disclosed for decoding multiplexed information in a chromatographic system. Implementations may include the method of pulsing ions from an ion source through an analyzer according to a predetermined multiplexing scheme, each pulse including one or more ions corresponding to a sample, detecting a plurality of ion strikes at a detector, determining a data point for each ion strike, wherein each data point includes an intensity of a detected ion strike and a time of the detected ion strike, maintaining a multiplexed spectrum of the data points, the multiplexed spectrum including the data points, and demultiplexing the time shifted spectrum using the data points of the multiplexed spectrum.
摘要:
A data acquisition system and method are described that may be used with various spectrometers. The data acquisition system may include an ion detector, an initial processing module, and a spectra processing module. The initial processing module is provided for processing the ion detection signals and for supplying processed signals to the spectra processing module. The spectra processing module generates spectra from the processed signals and supplies the generated spectra to an external processor for post-processing. The spectra processing module may include an ion statistics filter and/or a peak histogram filtering circuit.
摘要:
A method for processing chromatographic peaks in chromatographic systems comprising comparing a first peak with a second peak; and determining whether the first peak and second peak should be grouped together.