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公开(公告)号：US09925112B2
公开(公告)日：2018-03-27
申请号：US14588230
申请日：2014-12-31
申请人： L'Oreal
发明人： Elisa Caberlotto , Zane Bowman Allen Miller , Laetitia Ruiz , Aaron David Poole , Gerald Keith Brewer
CPC分类号： A61H15/0085 , A61H7/005 , A61H23/02 , A61H2201/1685 , A61H2201/169 , A61H2201/5007 , A61H2201/5046 , A61H2201/5058
摘要： The disclosed embodiments provide skin stimulating devices and methods that address the aging effects of skin at a protein level. Particularly, cyclical mechanical strain is used to regulate specific proteins within the skin, so as to produce specific effects. As a non-limiting example, the disclosed embodiments can be used to increase the production of certain proteins (e.g., hyaluronan synthase 3 (HAS3); fibronectin; tropoelastin; procoll1; integrin, etc.) in the skin, which results in anti-aging effects by increasing epidermal cohesion.
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公开(公告)号：US10098808B2
公开(公告)日：2018-10-16
申请号：US14587587
申请日：2014-12-31
申请人： L'Oreal
摘要： An end effector is capable of being used to stimulate a portion of skin at a stimulation frequency. The end effector includes a base portion that is couplable to a motor and an end portion having a plurality of contact points at which the end effector is configured to contact the portion of skin. The plurality of contact points are located at a target distance from each other that is based on an inverse of the stimulation frequency. The end effector is configured such that, when the base portion is coupled to the motor and the motor is operating, the end effector has a resonant frequency based on the stimulation frequency. When the motor is operating and a force is applied to bias the end effector toward the portion of skin, a cyclical stimulus is produced within the portion of skin at about the stimulation frequency.
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公开(公告)号：US09925113B2
公开(公告)日：2018-03-27
申请号：US14588255
申请日：2014-12-31
申请人： L'Oreal
发明人： Elisa Caberlotto , Zane Bowman Allen Miller , Laetitia Ruiz , Aaron David Poole , Gerald Keith Brewer
CPC分类号： A61H15/0085 , A46B13/008 , A46B13/02 , A46B2200/102 , A61H7/005 , A61H23/02 , A61H2201/1685 , A61H2201/169 , A61H2201/1692 , A61H2201/5007 , A61H2201/5046 , A61H2201/5058
摘要： The disclosed embodiments provide skin stimulating devices and methods that address the aging effects of skin at a protein level. Particularly, cyclical mechanical strain is used to regulate specific proteins within the skin, so as to produce specific effects. As a non-limiting example, the disclosed embodiments can be used to increase the production of certain proteins (e.g., hyaluronan synthase 3 (HAS3); fibronectin; tropoelastin; procoll1; integrin, etc.) in the skin, which results in anti-aging effects by increasing epidermal cohesion.
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4.发明申请SYSTEMS AND METHODS FOR REGULATION OF ONE OR MORE EPIDERMAL OR DERMOEPIDERMAL PROTEINS 有权调节一种或多种表皮或非真菌蛋白质的系统和方法公开(公告)号：US20160184177A1
公开(公告)日：2016-06-30
申请号：US14588255
申请日：2014-12-31
申请人： L'OREAL
IPC分类号： A61H15/00
CPC分类号： A61H15/0085 , A46B13/008 , A46B13/02 , A46B2200/102 , A61H7/005 , A61H23/02 , A61H2201/1685 , A61H2201/169 , A61H2201/1692 , A61H2201/5007 , A61H2201/5046 , A61H2201/5058
摘要： The disclosed embodiments provide skin stimulating devices and methods that address the aging effects of skin at a protein level. Particularly, cyclical mechanical strain is used to regulate specific proteins within the skin, so as to produce specific effects. As a non-limiting example, the disclosed embodiments can be used to increase the production of certain proteins (e.g., hyaluronan synthase 3 (HAS3); fibronectin; tropoelastin; procoll1; integrin, etc.) in the skin, which results in anti-aging effects by increasing epidermal cohesion.
摘要翻译： 所公开的实施方案提供了在蛋白质水平上解决皮肤老化作用的皮肤刺激装置和方法。 特别地，循环机械应变用于调节皮肤内的特定蛋白质，以产生特定的效果。 作为非限制性实例，所公开的实施方案可用于增加皮肤中某些蛋白质（例如，透明质酸合酶3（HAS3）;纤连蛋白;原丝胶蛋白;前胶蛋白1;整联蛋白等）的产生， 增加表皮凝聚力的老化作用。
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公开(公告)号：US20160184176A1
公开(公告)日：2016-06-30
申请号：US14588230
申请日：2014-12-31
申请人： L'OREAL
IPC分类号： A61H15/00
CPC分类号： A61H15/0085 , A61H7/005 , A61H23/02 , A61H2201/1685 , A61H2201/169 , A61H2201/5007 , A61H2201/5046 , A61H2201/5058
摘要： The disclosed embodiments provide skin stimulating devices and methods that address the aging effects of skin at a protein level. Particularly, cyclical mechanical strain is used to regulate specific proteins within the skin, so as to produce specific effects. As a non-limiting example, the disclosed embodiments can be used to increase the production of certain proteins (e.g., hyaluronan synthase 3 (HAS3); fibronectin; tropoelastin; procoll1; integrin, etc.) in the skin, which results in anti-aging effects by increasing epidermal cohesion.
摘要翻译： 所公开的实施方案提供了在蛋白质水平上解决皮肤老化作用的皮肤刺激装置和方法。 特别地，循环机械应变用于调节皮肤内的特定蛋白质，以产生特定的效果。 作为非限制性实例，所公开的实施方案可用于增加皮肤中某些蛋白质（例如，透明质酸合酶3（HAS3）;纤连蛋白;原丝胶蛋白;前胶蛋白1;整联蛋白等）的产生， 增加表皮凝聚力的老化作用。
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公开(公告)号：US20160184171A1
公开(公告)日：2016-06-30
申请号：US14587587
申请日：2014-12-31
申请人： L'Oreal
CPC分类号： A61H7/00 , A61H1/00 , A61H7/005 , A61H23/02 , A61H2201/0153 , A61H2201/0165 , A61H2201/105 , A61H2201/1223 , A61H2201/1654 , A61H2201/1669 , A61H2201/1671 , A61H2201/1685
摘要： An end effector is capable of being used to stimulate a portion of skin at a stimulation frequency. The end effector includes a base portion that is couplable to a motor and an end portion having a plurality of contact points at which the end effector is configured to contact the portion of skin. The plurality of contact points are located at a target distance from each other that is based on an inverse of the stimulation frequency. The end effector is configured such that, when the base portion is coupled to the motor and the motor is operating, the end effector has a resonant frequency based on the stimulation frequency. When the motor is operating and a force is applied to bias the end effector toward the portion of skin, a cyclical stimulus is produced within the portion of skin at about the stimulation frequency.
摘要翻译： 端部执行器能够用于以刺激频率刺激皮肤的一部分。 末端执行器包括可与电动机联接的基部部分和具有多个接触点的端部，末端执行器构造成与皮肤部分接触。 多个接触点位于基于刺激频率的倒数的彼此之间的目标距离处。 末端执行器构造成使得当基部联接到马达并且马达运行时，末端执行器具有基于刺激频率的共振频率。 当电动机运行并施加力以将末端执行器偏向皮肤部分时，在刺激频率附近在皮肤部分内产生循环刺激。
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公开(公告)号：US20180271742A1
公开(公告)日：2018-09-27
申请号：US15934703
申请日：2018-03-23
申请人： L'Oreal
发明人： Elisa Caberlotto , Zane Bowman Allen Miller , Laetitia Ruiz , Aaron David Poole , Gerald Keith Brewer
CPC分类号： A61H7/005 , A61H15/0085 , A61H23/02 , A61H23/0245 , A61H23/0254 , A61H2023/0209 , A61H2201/1685 , A61H2201/169 , A61H2201/1692 , A61H2201/5007 , A61H2201/5046 , A61H2201/5058
摘要： The disclosed embodiments provide skin stimulating devices and methods that address the aging effects of skin at a protein level. Particularly, cyclical mechanical strain is used to regulate specific proteins within the skin, so as to produce specific effects. As a non-limiting example, the disclosed embodiments can be used to increase the production of certain proteins (e.g., hyaluronan synthase 3 (HAS3); fibronectin; tropoelastin; procoll1; integrin, etc.) in the skin, which results in anti-aging effects by increasing epidermal cohesion.
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公开(公告)号：US09925111B2
公开(公告)日：2018-03-27
申请号：US14588209
申请日：2014-12-31
申请人： L'Oreal
发明人： Elisa Caberlotto , Zane Bowman Allen Miller , Laetitia Ruiz , Aaron David Poole , Gerald Keith Brewer
CPC分类号： A61H7/005 , A61H15/0085 , A61H23/02 , A61H2201/1685 , A61H2201/169 , A61H2201/1692 , A61H2201/5007 , A61H2201/5046 , A61H2201/5058
摘要： The disclosed embodiments provide skin stimulating devices and methods that address the aging effects of skin at a protein level. Particularly, cyclical mechanical strain is used to regulate specific proteins within the skin, so as to produce specific effects. As a non-limiting example, the disclosed embodiments can be used to increase the production of certain proteins (e.g., hyaluronan synthase 3 (HAS3); fibronectin; tropoelastin; procoll1; integrin, etc.) in the skin, which results in anti-aging effects by increasing epidermal cohesion.
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公开(公告)号：US20160184175A1
公开(公告)日：2016-06-30
申请号：US14588209
申请日：2014-12-31
申请人： L'Oreal
IPC分类号： A61H15/00
CPC分类号： A61H7/005 , A61H15/0085 , A61H23/02 , A61H2201/1685 , A61H2201/169 , A61H2201/1692 , A61H2201/5007 , A61H2201/5046 , A61H2201/5058
摘要： The disclosed embodiments provide skin stimulating devices and methods that address the aging effects of skin at a protein level. Particularly, cyclical mechanical strain is used to regulate specific proteins within the skin, so as to produce specific effects. As a non-limiting example, the disclosed embodiments can be used to increase the production of certain proteins (e.g., hyaluronan synthase 3 (HAS3); fibronectin; tropoelastin; procoll1; integrin, etc.) in the skin, which results in anti-aging effects by increasing epidermal cohesion.
摘要翻译： 所公开的实施方案提供了在蛋白质水平上解决皮肤老化作用的皮肤刺激装置和方法。 特别地，循环机械应变用于调节皮肤内的特定蛋白质，以产生特定的效果。 作为非限制性实例，所公开的实施方案可用于增加皮肤中某些蛋白质（例如，透明质酸合酶3（HAS3）;纤连蛋白;原丝胶蛋白;前胶蛋白1;整联蛋白等）的产生， 增加表皮凝聚力的老化作用。
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