公开(公告)号：US12171768B2

公开(公告)日：2024-12-24

申请号：US17651201

申请日：2022-02-15

Applicant: Kymera Therapeutics, Inc.

Inventor： Jared Gollob ,  Jeffrey Davis ,  Alice Mcdonald ,  Haojing Rong

IPC: A61K31/5386 ,  A61K9/00 ,  A61K9/20 ,  A61K9/28 ,  A61P31/00

Abstract: The present invention provides IRAK4 degraders, formulations and unit dosage forms thereof, and methods of use thereof.

公开(公告)号：US20230277519A1

公开(公告)日：2023-09-07

申请号：US18154454

申请日：2023-01-13

Applicant: Kymera Therapeutics, Inc.

Inventor： Jared Gollob ,  Jeffrey Davis ,  Ashwin Gollerkeri ,  Reginald EWESUEDO ,  Alice McDonald ,  Vashali Dixit ,  Shu-Pei Wu ,  Michele Mayo ,  Haojing Rong ,  Sagar Agarwal ,  Bradley Enerson ,  Patrick Henrick ,  Rachelle Perea ,  Christopher Ho ,  William Leong ,  Duncan Walker

IPC: A61K31/4545 ,  A61P35/00

CPC classification number: A61K31/4545 ,  A61P35/00

Abstract: The present invention relates to IRAKIMiD degraders, their liquid formulations, and methods of use thereof for treating cancer.