公开(公告)号：US11492334B2

公开(公告)日：2022-11-08

申请号：US17253823

申请日：2020-01-31

申请人： Kumiai Chemical Industry Co., Ltd.

发明人： Ryuji Tamai ,  Yukio Uchida ,  Fumiaki Takabe ,  Akira Kato ,  Ryo Maruyama ,  Ryo Kobayashi

IPC分类号： C07D241/44 ,  C07C213/08

摘要： A method for producing a nitroso compound of the following formula (3), comprising reacting a compound of the following formula (1) with a compound of the following formula (2) by using a tertiary alcohol and a base. wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9 are each independently a hydrogen atom, a halogen atom, a (C1-C4) alkyl, or a (C1-C4) alkoxy.

公开(公告)号：US20230012374A1

公开(公告)日：2023-01-12

申请号：US17773227

申请日：2020-10-30

申请人： KUMIAI CHEMICAL INDUSTRY CO., LTD.

发明人： Yukio Uchida ,  Naoya Atsumi ,  Shinki Tani ,  Koji Okada ,  Yuta Murai ,  Arnott Caoimhin

IPC分类号： C07D413/12 ,  A01N43/80

摘要： The present invention provides industrially preferable processes for producing a sulfone derivative useful as a herbicide and an intermediate thereof. Provided are a process for producing a compound of the formula (4), comprising the following step ii: (step ii) a step of reacting a compound of the formula (2) with a compound of the formula (3) in the presence of a base to produce the compound of the formula (4), and a process for producing a compound of the formula (5), comprising the following step iii: (step iii) a step of reacting the compound of the formula (4) with hydrogen peroxide in the presence of a metal catalyst to produce the compound of the formula (5).

公开(公告)号：US20210253539A1

公开(公告)日：2021-08-19

申请号：US17253823

申请日：2020-01-31

申请人： Kumiai Chemical Industry Co., Ltd.

发明人： Ryuji Tamai ,  Yukio Uchida ,  Fumiaki Takabe ,  Akira Kato ,  Ryo Maruyama ,  Ryo Kobayashi

IPC分类号： C07D241/44 ,  C07C213/08

摘要： A method for producing a nitroso compound of the following formula (3), comprising reacting a compound of the following formula (1) with a compound of the following formula (2) by using a tertiary alcohol and a base. wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9 are each independently a hydrogen atom, a halogen atom, a (C1-C4) alkyl, or a (C1-C4) alkoxy.

公开(公告)号：US12122755B2

公开(公告)日：2024-10-22

申请号：US17954740

申请日：2022-09-28

申请人： Kumiai Chemical Industry Co., Ltd.

发明人： Ryuji Tamai ,  Yukio Uchida ,  Fumiaki Takabe ,  Akira Kato ,  Ryo Maruyama ,  Ryo Kobayashi

IPC分类号： C07D241/44 ,  C07C213/08

CPC分类号： C07D241/44 ,  C07C213/08 ,  C07C2601/16

摘要： A method for producing a compound of a formula (3), including reacting a compound of a formula (1) with a compound of a formula (2) by using a tertiary alcohol and a base:




where R1, R2, R3, R4, R5, R6, R7, R8, and R9 are each independently a hydrogen atom, a halogen atom, a (C1-C4)alkyl, or a (C1-C4)alkoxy, the amount of the base used is 2.0-4.0 equivalents per 1 equivalent of the compound of formula (2), the amount of the tertiary alcohol used is 0.3-2.5 equivalents per 1 equivalent of the compound of formula (2), the base is a plurality of compounds comprising a lithium-containing base as a first compound, and a second compound selected from the group consisting of alkali metal hydrides, alkali metal amides, alkoxides, alkyl metals, alkali metals, and organic bases, and the reaction is performed in the presence of an aromatic hydrocarbon solvent.

公开(公告)号：US20230074836A1

公开(公告)日：2023-03-09

申请号：US17954740

申请日：2022-09-28

申请人： Kumiai Chemical Industry Co., Ltd.

发明人： Ryuji Tamai ,  Yukio Uchida ,  Fumiaki Takabe ,  Akira Kato ,  Ryo Maruyama ,  Ryo Kobayashi

IPC分类号： C07D241/44 ,  C07C213/08

摘要： A method for producing a compound of a formula (3), including reacting a compound of a formula (1) with a compound of a formula (2) by using a tertiary alcohol and a base: where R1, R2, R3, R4, R5, R6, R7, R8, and R9 are each independently a hydrogen atom, a halogen atom, a (C1-C4)alkyl, or a (C1-C4)alkoxy, the amount of the base used is 2.0-4.0 equivalents per 1 equivalent of the compound of formula (2), the amount of the tertiary alcohol used is 0.3-2.5 equivalents per 1 equivalent of the compound of formula (2), the base is a plurality of compounds comprising a lithium-containing base as a first compound, and a second compound selected from the group consisting of alkali metal hydrides, alkali metal amides, alkoxides, alkyl metals, alkali metals, and organic bases, and the reaction is performed in the presence of an aromatic hydrocarbon solvent.