公开(公告)号：US11492334B2

公开(公告)日：2022-11-08

申请号：US17253823

申请日：2020-01-31

Applicant: Kumiai Chemical Industry Co., Ltd.

Inventor： Ryuji Tamai ,  Yukio Uchida ,  Fumiaki Takabe ,  Akira Kato ,  Ryo Maruyama ,  Ryo Kobayashi

IPC: C07D241/44 ,  C07C213/08

Abstract: A method for producing a nitroso compound of the following formula (3), comprising reacting a compound of the following formula (1) with a compound of the following formula (2) by using a tertiary alcohol and a base. wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9 are each independently a hydrogen atom, a halogen atom, a (C1-C4) alkyl, or a (C1-C4) alkoxy.

公开(公告)号：US20210253539A1

公开(公告)日：2021-08-19

申请号：US17253823

申请日：2020-01-31

Applicant: Kumiai Chemical Industry Co., Ltd.

Inventor： Ryuji Tamai ,  Yukio Uchida ,  Fumiaki Takabe ,  Akira Kato ,  Ryo Maruyama ,  Ryo Kobayashi

IPC: C07D241/44 ,  C07C213/08

Abstract: A method for producing a nitroso compound of the following formula (3), comprising reacting a compound of the following formula (1) with a compound of the following formula (2) by using a tertiary alcohol and a base. wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9 are each independently a hydrogen atom, a halogen atom, a (C1-C4) alkyl, or a (C1-C4) alkoxy.

公开(公告)号：US12122755B2

公开(公告)日：2024-10-22

申请号：US17954740

申请日：2022-09-28

Applicant: Kumiai Chemical Industry Co., Ltd.

Inventor： Ryuji Tamai ,  Yukio Uchida ,  Fumiaki Takabe ,  Akira Kato ,  Ryo Maruyama ,  Ryo Kobayashi

IPC: C07D241/44 ,  C07C213/08

CPC classification number: C07D241/44 ,  C07C213/08 ,  C07C2601/16

Abstract: A method for producing a compound of a formula (3), including reacting a compound of a formula (1) with a compound of a formula (2) by using a tertiary alcohol and a base:




where R1, R2, R3, R4, R5, R6, R7, R8, and R9 are each independently a hydrogen atom, a halogen atom, a (C1-C4)alkyl, or a (C1-C4)alkoxy, the amount of the base used is 2.0-4.0 equivalents per 1 equivalent of the compound of formula (2), the amount of the tertiary alcohol used is 0.3-2.5 equivalents per 1 equivalent of the compound of formula (2), the base is a plurality of compounds comprising a lithium-containing base as a first compound, and a second compound selected from the group consisting of alkali metal hydrides, alkali metal amides, alkoxides, alkyl metals, alkali metals, and organic bases, and the reaction is performed in the presence of an aromatic hydrocarbon solvent.

公开(公告)号：US20230074836A1

公开(公告)日：2023-03-09

申请号：US17954740

申请日：2022-09-28

Applicant: Kumiai Chemical Industry Co., Ltd.

Inventor： Ryuji Tamai ,  Yukio Uchida ,  Fumiaki Takabe ,  Akira Kato ,  Ryo Maruyama ,  Ryo Kobayashi

IPC: C07D241/44 ,  C07C213/08

Abstract: A method for producing a compound of a formula (3), including reacting a compound of a formula (1) with a compound of a formula (2) by using a tertiary alcohol and a base: where R1, R2, R3, R4, R5, R6, R7, R8, and R9 are each independently a hydrogen atom, a halogen atom, a (C1-C4)alkyl, or a (C1-C4)alkoxy, the amount of the base used is 2.0-4.0 equivalents per 1 equivalent of the compound of formula (2), the amount of the tertiary alcohol used is 0.3-2.5 equivalents per 1 equivalent of the compound of formula (2), the base is a plurality of compounds comprising a lithium-containing base as a first compound, and a second compound selected from the group consisting of alkali metal hydrides, alkali metal amides, alkoxides, alkyl metals, alkali metals, and organic bases, and the reaction is performed in the presence of an aromatic hydrocarbon solvent.