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公开(公告)号:US10589041B2
公开(公告)日:2020-03-17
申请号:US14424205
申请日:2013-08-27
发明人: Alex Hearn , Iain McDerment
摘要: An inhaler comprising a reservoir of an inhalable composition. A valve element moved by a flexible diaphragm and biased into a position in which it closes a composition flow path from a reservoir. A first air flow path is partly defined by one side of the diaphragm and a second air flow path is partly defined by the opposite side of the diaphragm. Each flow path has an outlet opening at an outlet end and the second flow path has an inlet upstream of the outlet end. The air flow paths are arranged such that suction at the outlet end causes a reduction in pressure in the first air flow path relative to the pressure in the second air flow path creating a pressure differential across the diaphragm that moves the valve element against the biasing force to open the composition flow path.
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公开(公告)号:US10543324B2
公开(公告)日:2020-01-28
申请号:US15205166
申请日:2016-07-08
发明人: Alex Hearn , Iain McDerment
摘要: An inhaler comprising a reservoir of an inhalable composition with an outlet at one end through which the inhalable composition is discharged. A non-metered breath-activated valve is provided between the one end and the reservoir, the breath-activated valve comprising a flow path extending from the reservoir to the outlet end. At least a portion of the flow path is a deformable tube. A clamping member pinches the deformable tube closed when no suction force is applied to the device and releases the tube to open the flow path when suction is applied at the outlet, to provide uninterrupted flow from the reservoir to the outlet.
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公开(公告)号:US10334876B2
公开(公告)日:2019-07-02
申请号:US15634898
申请日:2017-06-27
发明人: Alex Hearn
摘要: A simulated smoking device (1) comprising a simulated cigarette having a substantially cylindrical cigarette-like shape and a refill device (2, 50) having a substantially cuboid housing with a cigarette pack-like shape containing refill gas (32, 59) for the simulated cigarette and having means for selectively retaining the simulated cigarette. The simulated cigarette may be retained wholly within the housing. It may be retained at a location different from the refill location. A dose counter may be provided to give a visual indication of the doses in the refill device.
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公开(公告)号:US09980520B2
公开(公告)日:2018-05-29
申请号:US15126940
申请日:2015-03-19
CPC分类号: A24F47/008 , A24F15/18 , A61M11/001 , A61M15/06 , A61M16/20 , B67D7/0294
摘要: An inhaler comprising a reservoir of an inhalable composition, a heater to selectably volatilize at least some components of the composition, and a power source arranged to selectively supply electrical power to the heater when the user inhales from the inhaler. The power source is arranged to heat the heater to a temperature that will volatilize some, but not all of the components of the composition.
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公开(公告)号:US10561634B2
公开(公告)日:2020-02-18
申请号:US16447557
申请日:2019-06-20
发明人: Alex Hearn , Ritika Gupta , Moira Bowdrey
IPC分类号: A61K36/00 , A61K31/352 , A61M15/00 , A61K9/00 , A61K9/16 , A61M11/02 , A61K31/05 , A24F47/00 , A61M15/06 , A61K9/12
摘要: An inhalable composition for use as a medicament in the treatment of a subject wherein said composition comprises: one or more cannabinoids or a pharmaceutically acceptable derivative or salt thereof; a propellant; a monohydric or polyhydric alcohol; and a glycol and/or glycol ether, characterised in that the ratio of monohydric or polyhydric alcohol to glycol or glycol ether by weight is from 6:1 to 1:1, wherein the composition is administered in the form of an aerosol having a fine particle fraction of 60% or more.
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公开(公告)号:US09969544B2
公开(公告)日:2018-05-15
申请号:US14780486
申请日:2014-03-25
IPC分类号: B65D83/14 , B65D83/42 , B65D83/48 , A61M15/00 , A24F47/00 , A24B15/16 , B65B3/14 , B65B31/04 , A61M15/06
CPC分类号: B65D83/752 , A24B15/16 , A24F47/002 , A24F47/006 , A61M15/0093 , A61M15/06 , A61M2202/0468 , A61M2209/045 , B65B3/14 , B65B31/047 , B65D83/42 , B65D83/48 , A61M2202/0007
摘要: A pressurized refill canister containing a composition including a propellant. The canister has an outlet valve having a stem biased to a closed position by a first resilient member. The stem has a maximum outer diameter of greater than 3 mm. At the outlet end of the stem, at least part of the wall of the stem extends inwardly from the outside diameter for at least 50% of the radius.
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公开(公告)号:US09918961B2
公开(公告)日:2018-03-20
申请号:US14622205
申请日:2015-02-13
发明人: Alex Hearn , Ritika Gupta , Moira Bowdrey
CPC分类号: A61K31/352 , A61K9/008 , A61K31/05 , A61K47/10 , A61M11/02 , A61M15/0093 , A61M15/06 , A61M2202/0468 , A61M2202/0007
摘要: The present invention provides a cannabinoid inhaler, compositions, and methods for delivering a cannabinoid composition to a subject. The cannabinoid composition is delivered in the form of inhaled droplets of respirable size via pulmonary administration. The invention may be used in the treatment of a condition or disorder selected from the group consisting of neuropathic pain, cannabis addiction, nausea, motion sickness, arthritis, and neurodegenerative disease.
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公开(公告)号:US20150217067A1
公开(公告)日:2015-08-06
申请号:US14424205
申请日:2013-08-27
发明人: Alex Hearn , Iain McDerment
IPC分类号: A61M15/00
摘要: An inhaler comprising a reservoir of an inhalable composition. A valve element moved by a flexible diaphragm and biased into a position in which it closes a composition flow path from a reservoir. A first air flow path is partly defined by one side of the diaphragm and a second air flow path is partly defined by the opposite side of the diaphragm. Each flow path has an outlet opening at an outlet end and the second flow path has an inlet upstream of the outlet end. The air flow paths are arranged such that suction at the outlet end causes a reduction in pressure in the first air flow path relative to the pressure in the second air flow path creating a pressure differential across the diaphragm that moves the valve element against the biasing force to open the composition flow path.
摘要翻译: 一种吸入器,包括可吸入组合物的储存器。 阀元件通过柔性隔膜移动并被偏压到从储存器封闭组合物流动路径的位置。 第一空气流路部分地由隔膜的一侧限定,并且第二空气流动路径部分地由隔膜的相对侧限定。 每个流动路径在出口端处具有出口开口,并且第二流动路径在出口端的上游具有入口。 空气流动路径被布置成使得在出口端处的吸力相对于第二空气流路中的压力导致第一空气流动路径中的压力降低,从而产生横跨隔膜的压力差,该压力差使阀元件抵抗偏置力移动 打开组合流路径。
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公开(公告)号:US10542778B2
公开(公告)日:2020-01-28
申请号:US15126980
申请日:2015-03-19
摘要: A combination of an inhaler and a refill pack. The inhaler comprises a reservoir for an inhalable composition, a heating element and/or vibrating transducer to selectively volatilise at least some components of the composition and at least one inhaler capacitor arranged to supply electrical power to the heater and/or vibrating transducer when a user inhales from the inhaler. The refill pack comprises a refill reservoir of inhalable composition and a battery coupled to a refill capacitor, and is arranged to engage with the inhaler and to simultaneously refill the reservoir and recharge the inhaler capacitor from the refill capacitor. The invention also extends to the inhaler and refill pack separately and to a method of refilling and recharging the inhaler.
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