Gene encoding a putative efflux protein for solvents/antibiotics in pseudomonas mendocina
    1.
    发明授权
    Gene encoding a putative efflux protein for solvents/antibiotics in pseudomonas mendocina 失效
    基因编码假单胞菌中溶剂/抗生素的推定外排蛋白

    公开(公告)号:US06225089B1

    公开(公告)日:2001-05-01

    申请号:US09333208

    申请日:1999-06-15

    申请人: Kevin Keqin Chen

    发明人: Kevin Keqin Chen

    IPC分类号: C12P2106

    摘要: This invention relates to the isolation of a novel putative efflux gene from Pseudomonas mendocina. The putative efflux gene is useful for probing an organism's efflux system to gain an understanding of the mechanisms of solvent tolerance. The invention further provides a Pseudomonas mendocina strain deficient in this gene. This strain is unable to grow in the presence of chloramphenicol and, compared to the wildtype strain, grows slowly in the presence of high concentrations of PHBA.

    摘要翻译: 本发明涉及从门氏假单胞菌(Pseudomonas mendocina)中分离出一种新的推定流出基因。 推定的流出基因可用于探测生物体的外排系统,以了解溶剂耐受机制。 本发明还提供了缺乏该基因的假单胞菌门氏菌属菌株。 该菌株在氯霉素存在下不能生长,并且与野生型菌株相比,在高浓度PHBA存在下生长缓慢。

    Gene encoding a putive efflux protein for solvents/antibiotics in Pseudomonas mendocina
    2.
    发明授权
    Gene encoding a putive efflux protein for solvents/antibiotics in Pseudomonas mendocina 失效
    基因编码假单胞菌中溶剂/抗生素的推定外排蛋白

    公开(公告)号:US06410265B1

    公开(公告)日:2002-06-25

    申请号:US09183270

    申请日:1998-10-30

    申请人: Kevin Keqin Chen

    发明人: Kevin Keqin Chen

    IPC分类号: G01N3300

    摘要: This invention relates to the isolation of a novel putative efflux gene from Pseudomonas mendocina. The putative efflux gene is useful for probing an organism's efflux system to gain an understanding of the mechanisms of solvent tolerance. The invention further provides a Pseudomonas mendocina strain deficient in this gene. This strain is unable to grow in the presence of chloramphenicol and, compared to the wildtype strain, grows slowly in the presence of high concentrations of PHBA.

    摘要翻译: 本发明涉及从门氏假单胞菌(Pseudomonas mendocina)中分离出一种新的推定流出基因。 推定的流出基因可用于探测生物体的外排系统,以了解溶剂耐受机制。 本发明还提供了缺乏该基因的假单胞菌门氏菌属菌株。 该菌株在氯霉素存在下不能生长,并且与野生型菌株相比,在高浓度PHBA存在下生长缓慢。