-
公开(公告)号：US09091605B2
公开(公告)日：2015-07-28
申请号：US14114071
申请日：2012-04-20
摘要： The force calculation system of the present invention is provided with: an air blowing unit for blowing air at a predetermined pressure; a flow passage for air blown from air blowing unit; a sensing unit for changing the ease of flow of air that flows through a flow passage by deforming when an external force is given; a storage unit for storing in advance the flow volume-force correspondence information showing the correspondence between the magnitude of the force received by the sensing unit and the flow volume at which air blown from air blowing unit flows through the flow passage; and a processing unit for calculating the magnitude of external force received by the sensing unit, on the basis of: the flow volume of air flowing through the flow passage as measured by a flow volume meter; and the flow volume-force correspondence information stored in the storage unit.
摘要翻译： 本发明的力计算系统设有：用于以预定压力吹送空气的送风单元; 吹气单元吹出空气的流路; 感测单元，用于通过在施加外力时通过变形而改变流过流路的空气流动的容易性; 存储单元，用于预先存储表示由感测单元接收的力的大小与从吹气单元吹送的空气流过流路的流量之间的对应关系的流量对应信息; 以及处理单元，其基于由流量计测量的流过所述流路的空气的流量，计算由所述感测单元接收的外力的大小; 以及存储在存储单元中的流量 - 力对应信息。
-
公开(公告)号：US20140047929A1
公开(公告)日：2014-02-20
申请号：US14114071
申请日：2012-04-20
IPC分类号： G01L1/02
摘要： The force calculation system of the present invention is provided with: an air blowing unit for blowing air at a predetermined pressure; a flow passage for air blown from air blowing unit; a sensing unit for changing the ease of flow of air that flows through a flow passage by deforming when an external force is given; a storage unit for storing in advance the flow volume-force correspondence information showing the correspondence between the magnitude of the force received by the sensing unit and the flow volume at which air blown from air blowing unit flows through the flow passage; and a processing unit for calculating the magnitude of external force received by the sensing unit, on the basis of the flow volume of air flowing through the flow passage as measured by a flow volume meter; and the flow volume-force correspondence information stored in the storage unit.
摘要翻译： 本发明的力计算系统设有：用于以预定压力吹送空气的送风单元; 吹气单元吹出空气的流路; 感测单元，用于通过在施加外力时通过变形而改变流过流路的空气流动的容易性; 存储单元，用于预先存储表示由感测单元接收的力的大小与从吹气单元吹送的空气流过流路的流量之间的对应关系的流量对应信息; 以及处理单元，其基于由流量计测量的流过所述流路的空气的流量来计算由所述感测单元接收的外力的大小; 以及存储在存储单元中的流量 - 力对应信息。
-
公开(公告)号：US08897916B2
公开(公告)日：2014-11-25
申请号：US13843174
申请日：2013-03-15
申请人： Kenji Kawashima , Kotaro Tadano
发明人： Kenji Kawashima , Kotaro Tadano
CPC分类号： B25J18/02 , B25J3/04 , B25J9/1689 , B25J13/025 , Y10S901/22 , Y10S901/34 , Y10T74/20305
摘要： A compact, lightweight manipulation system that excels in operability and has a force feedback capability is provided. When automatic operation of a slave manipulator 105 that follows manual operation of a master manipulator 101 is bilaterally controlled by means of communication, the force acting on the slave manipulator is fed back to the master manipulator by operating the master manipulator primarily under electrically-driven speed control and the slave manipulator primarily under pneumatically-driven force control. Therefore, in the master manipulator, it is not necessary to compensate for the dynamics and the self-weight of the master manipulator in the motion range of a user, allowing highly accurate, broadband positional control, which is specific to an electrically-driven system, and in the slave manipulator, nonlinearity characteristics specific to a pneumatically-driven system presents passive softness, provides a high mass-to-output ratio, and produces a large force.
摘要翻译： 提供了具有优异的可操作性和强力反馈功能的紧凑轻巧的操纵系统。 当主操纵器101的手动操作之后的从动操纵器105的自动操作通过通信进行双向控制时，作用在从动操纵器上的力通过主要在电动速度下操作主操纵器而被反馈给主操纵器 控制和从机械手主要在气动驱动力控制下。 因此，在主机械手中，不需要在用户的运动范围内补偿主机械手的动力学和自重，从而允许高精度的宽带位置控制，这是特定于电驱动系统 ，而在从动操纵器中，气动驱动系统特有的非线性特性呈现无源柔软性，提供了高质量 - 输出比，并产生较大的力。
-
公开(公告)号：US08700213B2
公开(公告)日：2014-04-15
申请号：US12529515
申请日：2008-02-29
申请人： Kenji Kawashima , Kotaro Tadano
发明人： Kenji Kawashima , Kotaro Tadano
CPC分类号： A61B19/2203 , A61B34/30 , A61B34/37 , A61B34/70 , A61B34/76 , A61B2017/2929 , A61B2034/304 , A61B2034/305 , A61B2090/064 , A61B2090/506 , B25J3/04 , B25J13/02 , B25J17/0266 , Y10T74/20305
摘要： A compact, lightweight manipulation system that excels in operability and has a force feedback capability is provided. When automatic operation of a slave manipulator 105 that follows manual operation of a master manipulator 101 is bilaterally controlled by means of communication, the force acting on the slave manipulator is fed back to the master manipulator by operating the master manipulator primarily under electrically-driven speed control and the slave manipulator primarily under pneumatically-driven force control. Therefore, in the master manipulator, it is not necessary to compensate for the dynamics and the self-weight of the master manipulator in the motion range of a user, allowing highly accurate, broadband positional control, which is specific to an electrically-driven system, and in the slave manipulator, nonlinearity characteristics specific to a pneumatically-driven system presents passive softness, provides a high mass-to-output ratio, and produces a large force.
-
公开(公告)号：US20100139436A1
公开(公告)日：2010-06-10
申请号：US12529515
申请日：2008-02-29
申请人： Kenji Kawashima , Kotaro Tadano
发明人： Kenji Kawashima , Kotaro Tadano
CPC分类号： A61B19/2203 , A61B34/30 , A61B34/37 , A61B34/70 , A61B34/76 , A61B2017/2929 , A61B2034/304 , A61B2034/305 , A61B2090/064 , A61B2090/506 , B25J3/04 , B25J13/02 , B25J17/0266 , Y10T74/20305
摘要： A compact, lightweight manipulation system that excels in operability and has a force feedback capability is provided.When automatic operation of a slave manipulator 105 that follows manual operation of a master manipulator 101 is bilaterally controlled by means of communication, the force acting on the slave manipulator is fed back to the master manipulator by operating the master manipulator primarily under electrically-driven speed control and the slave manipulator primarily under pneumatically-driven force control. Therefore, in the master manipulator, it is not necessary to compensate for the dynamics and the self-weight of the master manipulator in the motion range of a user, allowing highly accurate, broadband positional control, which is specific to an electrically-driven system, and in the slave manipulator, nonlinearity characteristics specific to a pneumatically-driven system presents passive softness, provides a high mass-to-output ratio, and produces a large force.
摘要翻译： 提供了具有优异的可操作性和强力反馈功能的紧凑轻巧的操纵系统。 当主操纵器101的手动操作之后的从动操纵器105的自动操作通过通信进行双向控制时，作用在从动操纵器上的力通过主要在电动速度下操作主操纵器而被反馈给主操纵器 控制和从机械手主要在气动驱动力控制下。 因此，在主机械手中，不需要在用户的运动范围内补偿主机械手的动力学和自重，从而允许高精度的宽带位置控制，这是特定于电驱动系统 ，而在从动操纵器中，气动驱动系统特有的非线性特性呈现无源柔软性，提供了高质量 - 输出比，并产生较大的力。
-
公开(公告)号：US08507485B2
公开(公告)日：2013-08-13
申请号：US12931072
申请日：2011-01-24
IPC分类号： A61K31/5377 , A61K31/506
CPC分类号： C07D401/14 , C07D239/42 , C07D401/12 , C07D409/12
摘要： A method of treating a disease associated with angiogenesis by administering a therapeutically effective amount of a compound represented by the formula (1) or a salt thereof wherein the ring X represents R1 and R2 independently represent a hydrogen atom, an alkyl, an aryl or an aromatic heterocyclic; R3 represents a hydrogen atom, a halogen atom, a hydroxy, an alkoxy, an aryloxy, an alkyl, an aryl, an amino, an alkylamino, a cycloalkylamino, an arylamino, an alkylcarbonylamino, an arylcarbonylamino, a mercapto, an alkylthio, an arylthio, an alkylsulfinyl or a nonaromatic heterocyclic; A1 represents a sulfur atom, a sulfinyl or a sulfonyl; and A2 represents an alkylene.
摘要翻译： 通过施用治疗有效量的由式（1）表示的化合物或其盐来治疗与血管生成相关的疾病的方法，其中环X表示R 1和R 2独立地表示氢原子，烷基，芳基或 芳香杂环; R 3表示氢原子，卤素原子，羟基，烷氧基，芳氧基，烷基，芳基，氨基，烷基氨基，环烷基氨基，芳基氨基，烷基羰基氨基，芳基羰基氨基，巯基，烷硫基 芳硫基，烷基亚磺酰基或非芳族杂环; A1表示硫原子，亚磺酰基或磺酰基; A2表示亚烷基。
-
7.发明授权1-2-dihydroquinoline derivative having glucocorticoid receptor binding activity 有权具有糖皮质激素受体结合活性的1-2-二氢喹啉衍生物公开(公告)号：US08017775B2
公开(公告)日：2011-09-13
申请号：US11992088
申请日：2006-09-14
申请人： Mamoru Matsuda , Toshiyuki Mori , Kenji Kawashima , Masato Nagatsuka , Sachiko Kobayashi , Minoru Yamamoto , Masatomo Kato , Miwa Takai , Tomoko Oda
发明人： Mamoru Matsuda , Toshiyuki Mori , Kenji Kawashima , Masato Nagatsuka , Sachiko Kobayashi , Minoru Yamamoto , Masatomo Kato , Miwa Takai , Tomoko Oda
IPC分类号： C07D215/38
CPC分类号： C07D215/14 , C07D215/20 , C07D215/48 , C07D401/04 , C07D401/12 , C07D405/12 , C07D409/12 , C07D417/12
摘要： An object of the present invention is to study synthesis of a novel 1,2-dihydroquinoline derivative and to find a pharmacological action of the derivative. A compound represented by the general formula (1) or a salt thereof is effective in the treatment of a glucocorticoid receptor-related disease. In the formula, the ring X represents a benzene ring or a pyridine ring; R1 represents a halogen atom, an alkyl group, a hydroxy group, an alkoxy group, an amino group or the like; p represents an integer of 0 to 5; R2 represents a halogen atom, an alkyl group, a hydroxy group or the like; q represents an integer of 0 to 2; R3 represents a hydrogen atom, an alkyl group, an alkenyl group or the like; R4 and R5 represent a hydrogen atom or the like; R6 represents a hydrogen atom or the like; A represents an alkylene group or the like; and R7 represents OR8, NR8R9, SR8, S(O)R8 or S(O)2R8, wherein R8 represents an aryl group, a heterocyclic group or the like and R9 represents a hydrogen atom or the like.
摘要翻译： 本发明的目的是研究新型1,2-二氢喹啉衍生物的合成，并找到衍生物的药理作用。 由通式（1）表示的化合物或其盐在治疗糖皮质激素受体相关疾病方面是有效的。 在该式中，环X表示苯环或吡啶环; R1表示卤素原子，烷基，羟基，烷氧基，氨基等; p表示0〜5的整数， R2表示卤素原子，烷基，羟基等; q表示0〜2的整数， R3表示氢原子，烷基，烯基等; R4和R5表示氢原子等; R6表示氢原子等; A表示亚烷基等; 并且R 7表示OR 8，NR 8 R 9，SR 8，S（O）R 8或S（O）2 R 8，其中R 8表示芳基，杂环基等，R 9表示氢原子等。
-
8.发明申请NOVEL INDOLE DERIVATIVE HAVING, CARBAMOYL GROUP, UREIDO GROUP AND SUBSTITUTED OXY GROUP 失效新加坡衍生产品有限公司，卡巴集团，乌代组和替代氧化集团公开(公告)号：US20110124668A1
公开(公告)日：2011-05-26
申请号：US13054041
申请日：2009-07-14
IPC分类号： A61K31/404 , C07D209/42 , C07D403/12 , A61K31/506 , C07D401/12 , A61K31/4439 , C07D405/10 , A61P29/00 , A61P27/06 , A61P17/00 , A61P27/02 , A61P35/00 , A61P3/00 , A61P25/00 , A61P37/06 , A61P31/00 , A61P37/08
CPC分类号： C07D209/42 , A61K31/404 , A61K31/4439 , A61K31/506 , C07D401/12 , C07D403/12 , C07D405/04
摘要： The present invention relates to synthetic studies on novel indole derivatives having a carbamoyl group, a ureido group and a substituted oxy group or a salt thereof, and pharmaceutical actions of the derivatives. The compound and a salt thereof represented by the general formula (1) has an IKKβ inhibitory activity and is useful as a preventive and/or therapeutic agent for diseases considered to be associated with IKKβ. In the formula, R1 represents a hydrogen atom, a lower alkyl group which may have a substituent, a hydroxy group, or a lower alkoxy group which may have a substituent, or the like; R2 represents a hydrogen atom, a lower alkyl group which may have a substituent, a lower cycloalkyl group which may have a substituent, an aryl group which may have a substituent, or a heterocyclic group which may have a substituent, or the like; R3 represents a halogen atom, a lower alkyl group which may have a substituent, a lower alkenyl group which may have a substituent, a lower alkynyl group which may have a substituent, a lower cycloalkyl group which may have a substituent, an aryl group which may have a substituent, a heterocyclic group which may have a substituent, or the like; m represents 0, 1, 2, or the like.
摘要翻译： 本发明涉及具有氨基甲酰基，脲基和取代的氧基或其盐的新型吲哚衍生物的合成研究以及衍生物的药物作用。 由通式（1）表示的化合物及其盐具有IKK＆bgr; 抑制活性，并且可用作被认为与IKK＆bgr相关的疾病的预防和/或治疗剂。 式中，R 1表示氢原子，可以具有取代基的低级烷基，羟基或可具有取代基的低级烷氧基等。 R2表示氢原子，可以具有取代基的低级烷基，可以具有取代基的低级环烷基，可以具有取代基的芳基或可以具有取代基的杂环基等。 R3表示卤原子，可以具有取代基的低级烷基，可以具有取代基的低级烯基，可以具有取代基的低级炔基，可以具有取代基的低级环烷基，可以具有取代基的低级环烷基， 可以具有取代基，可以具有取代基的杂环基等; m表示0,1,2等。
-
公开(公告)号：US20100030386A1
公开(公告)日：2010-02-04
申请号：US12445196
申请日：2007-10-10
申请人： Kenji Kawashima , Toshiharu Kagawa , Tomonori Kato
发明人： Kenji Kawashima , Toshiharu Kagawa , Tomonori Kato
CPC分类号： F16F15/027 , G05D16/2013
摘要： A pressure regulator for controlling pressure with high response and high accuracy even a flow change occurs on the downstream side. The pressure regulator (1) regulates the rate of inflow into an isothermal pressure vessel (13) for the gas supplied from a gas supply source (10) by means of a servo valve (11) to maintain the constant pressure in the isothermal pressure vessel (13). Pressure control means (a computer (16)) operating the servo valve (11) has as a main loop a pressure control system for feedback-controlling the pressure in the isothermal pressure vessel (13) measured by a pressure gauge (14) and has therein a rate-of-inflow-control system for feedback-controlling the rate of flow measured by a flow meter (12), an observer for estimating the rate of outflow from the isothermal pressure vessel (13) according to the rate of inflow and the derivative of the pressure in the isothermal pressure vessel (13) measured by a pressure differentiator (15), and a model follow-up control system for feed-backing the estimated rate of outflow to the rate-of-inflow control system.
摘要翻译： 在下游侧发生用于控制压力高的压力调节器，甚至具有高精度，甚至流量变化。 压力调节器（1）调节通过伺服阀（11）从气体供应源（10）供应的气体流入等温压力容器（13）的速率，以保持恒温压力容器 （13）。 操作伺服阀（11）的压力控制装置（计算机（16））具有作为主回路的压力控制系统，用于反馈控制由压力表（14）测量的等温压力容器（13）中的压力，并具有 其中具有用于反馈控制由流量计（12）测量的流量的流入速率控制系统，用于根据流入速率估计来自等温压力容器（13）的流出速率的观测器，以及 通过压力微分器（15）测量的等温压力容器（13）中的压力的导数，以及用于将流出量的估计流量提供给流入速率控制系统的模型跟踪控制系统。
-
公开(公告)号：US20080021064A1
公开(公告)日：2008-01-24
申请号：US11897308
申请日：2007-08-30
IPC分类号： A61K31/4709 , C07D401/02 , C07D409/02
CPC分类号： C07D215/12 , C07D215/20 , C07D401/12 , C07D401/14 , C07D409/12
摘要： The present invention relates to a synthesis study of novel cyclic compounds having a quinolylalkylthio group represented by the formula (1), and pharmacological actions of the compounds. In the formula, the ring X represents: which may have halogen and/or alkyl; R1 and R2 independently represent hydrogen, alkyl, cycloalkyl, aryl or a (non) aromatic heterocycle; R3 represents qinolyl; A represents sulfur, sulfinyl or sulfonyl; and B represents alkylene.
摘要翻译： 本发明涉及具有由式（1）表示的喹啉基烷硫基的新型环状化合物的合成研究以及该化合物的药理作用。 在该式中，环X表示：其可具有卤素和/或烷基; R 1和R 2独立地代表氢，烷基，环烷基，芳基或（非）芳族杂环; R 3表示喹啉基; A代表硫，亚磺酰基或磺酰基; B表示亚烷基。
-
-
-
-
-
-
-
-
-
搜索结果
44 条记录 (耗时 0.036 秒)
