-
公开(公告)号：US20120135922A1
公开(公告)日：2012-05-31
申请号：US13296120
申请日：2011-11-14
CPC分类号： C07K14/605 , A61K47/60
摘要： Novel modified exendins and exendin agonists having an exendin or exendin agonist linked to one or more polyethylene glycol polymers, for example, and related formulations and dosages and methods of administration thereof are provided. These modified exendins and exendin agonists, compositions and methods are useful in treating diabetes and conditions that would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying or inhibiting food intake.
摘要翻译： 提供了具有与一种或多种聚乙二醇聚合物连接的毒蜥外泌肽或毒蜥外泌激素的新型修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，以及相关的制剂和剂量以及施用方法。 这些修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，组合物和方法可用于治疗通过降低血浆葡萄糖或延迟和/或减缓胃排空或抑制食物摄取而受益的糖尿病和病症。
-
2.发明授权公开(公告)号：US07683030B2
公开(公告)日：2010-03-23
申请号：US12046038
申请日：2008-03-11
CPC分类号： C07K14/605 , A61K47/60
摘要： Modified exendins and exendin agonists having an exendin or exendin agonist linked to one or more polyethylene glycol polymers, for example, and related formulations and dosages and methods of administration thereof are provided. These modified exendins and exendin agonists, compositions and methods are useful in treating diabetes and conditions that would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying or inhibiting food intake.
摘要翻译： 提供了具有与一种或多种聚乙二醇聚合物连接的毒蜥外泌肽或毒蜥外泌激素的修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，以及相关的制剂和剂量以及施用方法。 这些修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，组合物和方法可用于治疗通过降低血浆葡萄糖或延迟和/或减缓胃排空或抑制食物摄取而受益的糖尿病和病症。
-
公开(公告)号：US06858576B1
公开(公告)日：2005-02-22
申请号：US08908867
申请日：1997-08-08
IPC分类号： A61K45/00 , A61K38/00 , A61K38/22 , A61P1/00 , A61P1/06 , C07K7/02 , C07K14/575 , A61K38/16 , A61K38/17 , A61K38/26 , C07K5/00
CPC分类号： C07K14/605 , A61K38/00 , A61K38/22 , A61K38/26 , C07K14/57563 , A61K2300/00
摘要： Methods for reducing gastric motility and delaying gastric emptying for therapeutic and diagnostic purposes are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist. Methods for treating conditions associated with elevated, inappropriate, or undesired post-prandial blood glucose levels are disclosed which comprise administration of an effective amount of an exendin or an exendin agonist alone or in conjunction with other anti-gastric emptying agents.
摘要翻译： 公开了减少胃动力和延迟胃排空用于治疗和诊断目的的方法，其包括施用有效量的毒蜥外泌肽或毒蜥外泌肽激动剂。 公开了治疗与升高的，不适当的或不期望的餐后血糖水平相关的病症的方法，其包括单独施用有效量的毒蜥外泌肽或毒蜥外泌肽激素，或与其他抗胃排空剂联合施用。
-
公开(公告)号：US07608692B2
公开(公告)日：2009-10-27
申请号：US12101689
申请日：2008-04-11
CPC分类号： C07K14/605 , A61K47/60
摘要： Modified exendins and exendin agonists having an exendin or exendin agonist linked to one or more polyethylene glycol polymers, for example, and related formulations and dosages and methods of administration thereof are provided. These modified exendins and exendin agonists, compositions and methods are useful in treating diabetes and conditions that would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying or inhibiting food intake.
摘要翻译： 提供了具有与一种或多种聚乙二醇聚合物连接的毒蜥外泌肽或毒蜥外泌激素的修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，以及相关的制剂和剂量以及施用方法。 这些修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，组合物和方法可用于治疗通过降低血浆葡萄糖或延迟和/或减缓胃排空或抑制食物摄取而受益的糖尿病和病症。
-
公开(公告)号：US20080176802A1
公开(公告)日：2008-07-24
申请号：US12046038
申请日：2008-03-11
CPC分类号： C07K14/605 , A61K47/60
摘要： Novel modified exendins and exendin agonists having an exendin or exendin agonist linked to one or more polyethylene glycol polymers, for example, and related formulations and dosages and methods of administration thereof are provided. These modified exendins and exendin agonists, compositions and methods are useful in treating diabetes and conditions that would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying or inhibiting food intake.
摘要翻译： 提供了具有与一种或多种聚乙二醇聚合物连接的毒蜥外泌肽或毒蜥外泌激素的新型修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，以及相关的制剂和剂量以及施用方法。 这些修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，组合物和方法可用于治疗通过降低血浆葡萄糖或延迟和/或减缓胃排空或抑制食物摄取而受益的糖尿病和病症。
-
公开(公告)号：US08445647B2
公开(公告)日：2013-05-21
申请号：US13296120
申请日：2011-11-14
CPC分类号： C07K14/605 , A61K47/60
摘要： Novel modified exendins and exendin agonists having an exendin or exendin agonist linked to one or more polyethylene glycol polymers, for example, and related formulations and dosages and methods of administration thereof are provided. These modified exendins and exendin agonists, compositions and methods are useful in treating diabetes and conditions that would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying or inhibiting food intake.
-
公开(公告)号：US20080200390A1
公开(公告)日：2008-08-21
申请号：US12101818
申请日：2008-04-11
CPC分类号： C07K14/605 , A61K47/60
摘要： Novel modified exendins and exendin agonists having an exendin or exendin agonist linked to one or more molecular weight increasing compounds, for example, polyamino acids, polyethylene glycol polymers, and related formulations and dosages and methods of administration thereof are provided. These modified exendins and exendin agonists, compositions and methods are useful in treating diabetes and conditions that would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying or inhibiting food intake.
摘要翻译： 提供了具有与一种或多种分子量增加化合物连接的毒蜥外泌肽或毒蜥外泌激素的新型修饰的毒蜥外泌肽和毒蜥外泌肽激素，例如聚氨基酸，聚乙二醇聚合物和相关制剂及其施用方法及剂量。 这些修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，组合物和方法可用于治疗通过降低血浆葡萄糖或延迟和/或减缓胃排空或抑制食物摄取而受益的糖尿病和病症。
-
公开(公告)号：US08057822B2
公开(公告)日：2011-11-15
申请号：US11174089
申请日：2005-06-30
CPC分类号： C07K14/605 , A61K47/60
摘要： Novel modified exendins and exendin agonists having an exendin or exendin agonist linked to one or more polyethylene glycol polymers, for example, and related formulations and dosages and methods of administration thereof are provided. These modified exendins and exendin agonists, compositions and methods are useful in treating diabetes and conditions that would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying or inhibiting food intake.
摘要翻译： 提供了具有与一种或多种聚乙二醇聚合物连接的毒蜥外泌肽或毒蜥外泌激素的新型修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，以及相关的制剂和剂量以及施用方法。 这些修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，组合物和方法可用于治疗通过降低血浆葡萄糖或延迟和/或减缓胃排空或抑制食物摄取而受益的糖尿病和病症。
-
公开(公告)号：US07691963B2
公开(公告)日：2010-04-06
申请号：US12101818
申请日：2008-04-11
CPC分类号： C07K14/605 , A61K47/60
摘要： Modified exendins and exendin agonists having an exendin or exendin agonist linked to one or more molecular weight increasing compounds, for example, polyamino acids, polyethylene glycol polymers, and related formulations and dosages and methods of administration thereof are provided. These modified exendins and exendin agonists, compositions comprising the modified exendin or the agonist thereof are useful in treating diabetes and conditions that would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying or inhibiting food intake.
摘要翻译： 提供了具有连接至一种或多种分子量增加化合物的毒蜥外泌肽或毒蜥外泌激素的修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，例如聚氨基酸，聚乙二醇聚合物，以及相关制剂及其给药方式及其施用方法。 这些修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，包含修饰的毒蜥外泌肽或其激动剂的组合物可用于治疗糖尿病和通过降低血浆葡萄糖或延迟和/或减缓胃排空或抑制食物摄取而受益的病症。
-
公开(公告)号：US20080214467A1
公开(公告)日：2008-09-04
申请号：US12101689
申请日：2008-04-11
CPC分类号： C07K14/605 , A61K47/60
摘要： Novel modified exendins and exendin agonists having an exendin or exendin agonist linked to one or more molecular weight increasing compounds, for example, albumin, polyethylene glycol polymers, and related formulations and dosages and methods of administration thereof are provided. These modified exendins and exendin agonists, compositions and methods are useful in treating diabetes and conditions that would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying or inhibiting food intake.
摘要翻译： 提供了具有与一种或多种分子量增加化合物连接的毒蜥外泌肽或毒蜥外泌激素的新型修饰的毒蜥外泌肽和毒蜥外苷激动剂，例如白蛋白，聚乙二醇聚合物，以及相关制剂及其给药方式及其施用方法。 这些修饰的毒蜥外泌肽和毒蜥外泌肽激动剂，组合物和方法可用于治疗通过降低血浆葡萄糖或延迟和/或减缓胃排空或抑制食物摄取而受益的糖尿病和病症。
-
-
-
-
-
-
-
-
-
搜索结果
73 条记录 (耗时 0.031 秒)
