公开(公告)号：US20180207132A1

公开(公告)日：2018-07-26

申请号：US15563926

申请日：2016-03-31

申请人： Kalyra Pharmaceuticals, Inc.

发明人： Peter Qinhua Huang ,  Mehmet Kahraman ,  Deborah Helen Slee ,  Kevin Duane Bunker ,  Chad Daniel Hopkins ,  Joseph Robert Pinchman ,  Sunny Abraham ,  Rakesh Kumar Sit ,  Daniel Lee Severance

IPC分类号： A61K31/4162 ,  A61K31/416 ,  A61P35/00

摘要： Disclosed herein are spirocyclic compounds, together with pharmaceutical compositions and methods of ameliorating and/or treating a cancer described herein with one or more of the compounds described herein.

公开(公告)号：US20170342055A1

公开(公告)日：2017-11-30

申请号：US15603789

申请日：2017-05-24

申请人： Kalyra Pharmaceuticals, Inc.

发明人： Kevin Duane Bunker ,  Peter Qinhua Huang ,  Sunny Abraham ,  Joseph Robert Pinchman ,  Chad Daniel Hopkins ,  Deborah Helen Slee

IPC分类号： C07D403/04 ,  C07D471/04 ,  C07D403/14

摘要： Disclosed herein are nitrogen-containing bicyclic compounds, together with pharmaceutical compositions and methods of ameliorating and/or treating a cancer described herein with one or more of the compounds described herein.

公开(公告)号：US10513509B2

公开(公告)日：2019-12-24

申请号：US15603789

申请日：2017-05-24

申请人： Kalyra Pharmaceuticals, Inc.

发明人： Kevin Duane Bunker ,  Peter Qinhua Huang ,  Sunny Abraham ,  Joseph Robert Pinchman ,  Chad Daniel Hopkins ,  Deborah Helen Slee

IPC分类号： C07D403/04 ,  C07D403/14 ,  C07D471/04 ,  A61K31/506 ,  A61P35/00

摘要： Disclosed herein are nitrogen-containing bicyclic compounds, together with pharmaceutical compositions and methods of ameliorating and/or treating a cancer described herein with one or more of the compounds described herein.

公开(公告)号：US20180201614A1

公开(公告)日：2018-07-19

申请号：US15572744

申请日：2016-05-10

申请人： KALYRA PHARMACEUTICALS, INC.

发明人： Kevin Duane Bunker ,  Sunny Abraham ,  Chad Daniel Hopkins ,  Joseph Robert Pinchman ,  Peter Qinhua Huang ,  Deborah Helen Slee

IPC分类号： C07D473/30 ,  C07D471/04 ,  C07D487/04 ,  A61P35/00

CPC分类号： C07D473/30 ,  A61P35/00 ,  C07D471/04 ,  C07D487/04

摘要： Disclosed herein are nitrogen-containing bicyclic compounds, together with pharmaceutical compositions and methods of ameliorating and/or treating a cancer described herein with one or more of the compounds described herein.